Employees – University of Copenhagen

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Department of Drug Design and Pharmacology > Employees

David E. Gloriam

David E. Gloriam

Associate Professor


  1. Published

    G protein- and agonist-bound serotonin 5-HT2A receptor model activated by steered molecular dynamics simulations. / Ísberg, Vignir; Balle, Thomas; Sander, Tommy; Jørgensen, Flemming Steen; Gloriam, David Erik Immanuel.

    In: Journal of Chemical Information and Modeling, Vol. 51, No. 2, 28.02.2011, p. 315-325.

    Publication: Research - peer-reviewJournal article

  2. Published

    GPCRDB : an information system for G protein-coupled receptors. / Ísberg, Vignir; Vroling, Bas; van der Kant, Rob; Li, Kang; Vriend, Gert; Gloriam, David.

    In: Nucleic Acids Research, Vol. 42, No. Database issue, 01.2014, p. D422-D425.

    Publication: Research - peer-reviewJournal article

  3. Published

    Computer-aided discovery of aromatic L-α-amino acids as agonists of the orphan G protein-coupled receptor GPR139. / Ísberg, Vignir; Andersen, Kirsten Bayer; Bisig, Christoph; Dietz, Gunnar Ph; Bräuner-Osborne, Hans; Gloriam, David Erik.

    In: Journal of chemical information and modeling, Vol. 54, No. 6, 14.05.2014, p. 1553-1557.

    Publication: Research - peer-reviewJournal article

  4. Published
  5. Published

    Modulation in selectivity and allosteric properties of small-molecule ligands for CC-chemokine receptors. / Thiele, Stefanie; Malmgaard-Clausen, Mikkel; Engel-Andreasen, Jens; Steen, Anne; Rummel, Pia C; Nielsen, Mads C; Gloriam, David E.; Frimurer, Thomas M; Ulven, Trond; Rosenkilde, Mette M.

    In: Journal of Medicinal Chemistry, Vol. 55, No. 18, 27.09.2012, p. 8164-77.

    Publication: Research - peer-reviewJournal article

  6. Published

    Editorial overview : New technologies: GPCR drug design and function-exploiting the current (of) structures. / Tautermann, Christofer S; Gloriam, David E.

    In: Current Opinion in Pharmacology, Vol. 30, 02.08.2016, p. 7-10.

    Publication: ResearchComment/debate

  7. ProteomeBinders : planning a European resource of affinity reagents for analysis of the human proteome. / Taussig, Michael J; Stoevesandt, Oda; Borrebaeck, Carl A K; Bradbury, Andrew R; Cahill, Dolores; Cambillau, Christian; de Daruvar, Antoine; Dübel, Stefan; Eichler, Jutta; Frank, Ronald; Gibson, Toby J; Gloriam, David E.; Gold, Larry; Herberg, Friedrich W; Hermjakob, Henning; Hoheisel, Jörg D; Joos, Thomas O; Kallioniemi, Olli; Koegl, Manfred; Koegll, Manfred; Konthur, Zoltán; Korn, Bernhard; Kremmer, Elisabeth; Krobitsch, Sylvia; Landegren, Ulf; van der Maarel, Silvère; McCafferty, John; Muyldermans, Serge; Nygren, Per-Ake; Palcy, Sandrine; Plückthun, Andreas; Polic, Bojan; Przybylski, Michael; Saviranta, Petri; Sawyer, Alan; Sherman, David J; Skerra, Arne; Templin, Markus; Ueffing, Marius; Uhlén, Mathias.

    In: Nature Methods, Vol. 4, No. 1, 01.2007, p. 13-7.

    Publication: Research - peer-reviewJournal article

  8. Published

    Identification of the first surrogate agonists for the G protein-coupled receptor GPR132. / Shehata, Mohamed A.; Christensen, Hanna Belcik; Isberg, Vignir; Pedersen, Daniel Sejer; Bender, Andreas; Bräuner-Osborne, Hans; Gloriam, David E.

    In: RSC Advances, Vol. 5, 2015, p. 48551-48557.

    Publication: Research - peer-reviewJournal article

  9. Published

    The GPR139 reference agonists 1a and 7c, and tryptophan and phenylalanine share a common binding site. / Shehata, Mohamed A.; Jensen, Anne Cathrine Nøhr; Jespers, Willem; Floryan, Leonard; Isberg, Vignir; Andersen, Kirsten Bayer; Åqvist, Johan; Gutiérrez-de-Terán, Hugo; Bräuner-Osborne, Hans; Gloriam, David E.

    In: Scientific Reports, Vol. 7, 1128, 25.04.2017.

    Publication: Research - peer-reviewJournal article

  10. Published

    Novel Agonist Bioisosteres and Common Structure-Activity Relationships for The Orphan G Protein-Coupled Receptor GPR139. / Shehata, Mohamed A; Jensen, Anne Cathrine Nøhr; Lissa, Delphine; Bisig, Christoph; Isberg, Vignir; Andersen, Kirsten B; Harpsøe, Kasper; Björkling, Fredrik; Bräuner-Osborne, Hans; Gloriam, David E.

    In: Scientific Reports, Vol. 6, 36681, 10.11.2016, p. 1-13.

    Publication: Research - peer-reviewJournal article

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