Employees – University of Copenhagen

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Department of Drug Design and Pharmacology > Employees

Hans Bräuner-Osborne

Hans Bräuner-Osborne

Professor


  1. Published

    (1S, 3S)-3-amino-4-difluoromethylenyl-1-cyclopentanoic acid (CPP-115), a potent gamma-aminobutyric acid aminotransferase inactivator for the treatment of cocaine addiction. / Pan, Yue; Gerasimov, Madina R; Kvist, Trine; Wellendorph, Petrine; Madsen, Karsten Kirkegaard; Pera, Elena; Lee, Hyunbeom; Schousboe, Arne; Chebib, Mary; Bräuner-Osborne, Hans; Craft, Cheryl M; Brodie, Jonathan D; Schiffer, Wynne K; Dewey, Stephen L; Miller, Stephen R; Silverman, Richard B.

    In: Journal of Medicinal Chemistry, Vol. 55, No. 1, 01.01.2012, p. 357-366.

    Publication: Research - peer-reviewJournal article

  2. Published

    (R)-(3-amino-2-fluoropropyl) phosphinic acid (AZD3355), a novel GABAB receptor agonist, inhibits transient lower esophageal sphincter relaxation through a peripheral mode of action. / Lehmann, Anders; Antonsson, Madeleine; Holmberg, Ann Aurell; Blackshaw, L. Ashley; Brändén, Lena; Bräuner-Osborne, Hans; Christiansen, Bolette; Dent, John; Elebring, Thomas; Jacobson, Britt-Marie; Jensen, Jörgen; Mattsson, Jan P.; Nilsson, Karolina; Oja, Simo S.; Page, Amanda J.; Saransaari, Pirjo; von Unge, Sverker.

    In: Journal of Pharmacology and Experimental Therapeutics, Vol. 331, No. 2, 2009, p. 504-512.

    Publication: Research - peer-reviewJournal article

  3. Published

    (S)-2-Amino-3-(3-hydroxy-7,8-dihydro-6H-cyclohepta[d]isoxazol-4-yl)propionic acid, a potent and selective agonist at the GluR5 subtype of ionotropic glutamate receptors. Synthesis, modeling, and molecular pharmacology. / Brehm, Lotte; Greenwood, Jeremy R; Hansen, Kasper B; Nielsen, Birgitte; Egebjerg, Jan; Stensbøl, Tine B; Bräuner-Osborne, Hans; Sløk, Frank A; Kronborg, Tine T A; Krogsgaard-Larsen, Povl.

    In: Journal of Medicinal Chemistry, Vol. 46, No. 8, 10.04.2003, p. 1350-8.

    Publication: Research - peer-reviewJournal article

  4. Published

    (S)-homo-AMPA, a specific agonist at the mGlu6 subtype of metabotropic glutamic acid receptors. / Ahmadian, H; Nielsen, B; Bräuner-Osborne, Hans; Johansen, T N; Stensbøl, T B; Sløk, F A; Sekiyama, N; Nakanishi, S; Krogsgaard-Larsen, P; Madsen, U.

    In: Journal of Medicinal Chemistry, Vol. 40, No. 22, 24.10.1997, p. 3700-5.

    Publication: Research - peer-reviewJournal article

  5. Published

    1,2,3-triazolyl amino acids as AMPA receptor ligands. / Stanley, Nathan J.; Pedersen, Daniel Sejer; Nielsen, Birgitte; Kvist, Trine; Mathiesen, Jesper M; Bräuner-Osborne, Hans; Taylor, Dennis K; Abell, Andrew D.

    In: Bioorganic & Medicinal Chemistry Letters, Vol. 20, No. 24, 15.12.2010, p. 7512-7515.

    Publication: Research - peer-reviewJournal article

  6. Published

    2-Amino-3-(3-hydroxy-1,2,5-thiadiazol-4-yl)propionic acid : resolution, absolute stereochemistry and enantiopharmacology at glutamate receptors. / Johansen, Tommy N; Janin, Yves L; Nielsen, Birgitte; Frydenvang, Karla Andrea; Bräuner-Osborne, Hans; Stensbøl, Tine B; Vogensen, Stine B; Madsen, Ulf; Krogsgaard-Larsen, Povl.

    In: Bioorganic & Medicinal Chemistry, Vol. 10, No. 7, 2002, p. 2259-66.

    Publication: Research - peer-reviewJournal article

  7. Published

    3-Substituted 2-phenyl-indoles : Privileged structures for medicinal chemistry. / Johansson, Karl Henrik; Jørgensen, T.B.; Gloriam, D.E.; Bräuner-Osborne, Hans; Pedersen, D.S.

    In: R S C Advances, Vol. 3, No. 3, 21.01.2013, p. 945-960.

    Publication: Research - peer-reviewJournal article

  8. Published

    3-pyrazolone analogues of the 3-isoxazolol metabotropic excitatory amino acid receptor agonist homo-AMPA. Synthesis and pharmacological testing. / Zimmermann, D.; Janin, Y.L.; Brehm, L.; Bräuner-Osborne, Hans; Ebert, B.; Johansen, T.N.; Madsen, U.; Krogsgaard-Larsen, P.

    In: European Journal of Medicinal Chemistry, Vol. 34, No. 11, 01.11.1999, p. 967-976.

    Publication: Research - peer-reviewJournal article

  9. Published

    3B but which 3B? And that's just one of the questions : the heterogeneity of human 5-HT3 receptors. / Jensen, Anders A.; Davies, Paul A.; Bräuner-Osborne, Hans; Krzywkowski, Karen.

    In: TIPS - Trends in Pharmacological Sciences, Vol. 29, No. 9, 2008, p. 437-444.

    Publication: Research - peer-reviewJournal article

  10. Published
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