Employees – University of Copenhagen

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Department of Drug Design and Pharmacology > Employees

Hans Bräuner-Osborne

Hans Bräuner-Osborne

Professor


  1. 2003
  2. Published

    Design, synthesis, and pharmacology of a highly subtype-selective GluR1/2 agonist, (RS)-2-amino-3-(4-chloro-3-hydroxy-5-isoxazolyl)propionic acid (Cl-HIBO). / Bjerrum, Esben J; Kristensen, Anders S; Pickering, Darryl S; Greenwood, Jeremy R; Nielsen, Birgitte; Liljefors, Tommy; Schousboe, Arne; Bräuner-Osborne, Hans; Madsen, Ulf; Pickering, Darryl.

    In: Journal of Medicinal Chemistry, Vol. 46, No. 11, 2003, p. 2246-9.

    Research output: Research - peer-reviewJournal article

  3. Published

    (S)-2-Amino-3-(3-hydroxy-7,8-dihydro-6H-cyclohepta[d]isoxazol-4-yl)propionic acid, a potent and selective agonist at the GluR5 subtype of ionotropic glutamate receptors. Synthesis, modeling, and molecular pharmacology. / Brehm, Lotte; Greenwood, Jeremy R; Hansen, Kasper B; Nielsen, Birgitte; Egebjerg, Jan; Stensbøl, Tine B; Bräuner-Osborne, Hans; Sløk, Frank A; Kronborg, Tine T A; Krogsgaard-Larsen, Povl.

    In: Journal of Medicinal Chemistry, Vol. 46, No. 8, 10.04.2003, p. 1350-8.

    Research output: Research - peer-reviewJournal article

  4. Published
  5. Published

    Synthesis and anticonvulsant activity of novel bicyclic acidic amino acids. / Conti, Paola; De Amici, Marco; Joppolo Di Ventimiglia, Samuele; Stensbøl, Tine B; Madsen, Ulf; Bräuner-Osborne, Hans; Russo, Emilio; De Sarro, Giovambattista; Bruno, Giuseppe; De Micheli, Carlo.

    In: Journal of Medicinal Chemistry, Vol. 46, No. 14, 03.07.2003, p. 3102-8.

    Research output: Research - peer-reviewJournal article

  6. Published

    Carbamoylcholine homologs : novel and potent agonists at neuronal nicotinic acetylcholine receptors. / Jensen, Anders A.; Frølund, Bente; Bräuner-Osborne, Hans; Falch, Erik; Krogsgaard-Larsen, Povl.

    In: Molecular Pharmacology, Vol. 64, No. 4, 2003, p. 865-75.

    Research output: Research - peer-reviewJournal article

  7. Published

    Specific gamma-hydroxybutyrate-binding sites but loss of pharmacological effects of gamma-hydroxybutyrate in GABA-B1-deficient mice. / Kaupmann, Klemens; Cryan, John F; Wellendorph, Petrine; Mombereau, Cedric; Sansig, Gilles; Klebs, Klaus; Schmutz, Markus; Froestl, Wolfgang; van der Putten, Herman; Mosbacher, Johannes; Bräuner-Osborne, Hans; Waldmeier, Peter; Bettler, Bernhard.

    In: European Journal of Neuroscience, Vol. 18, No. 10, 11.2003, p. 2722-30.

    Research output: Research - peer-reviewJournal article

  8. Published

    Positive allosteric modulation of the human metabotropic glutamate receptor 4 (hmGluR4) by SIB-1893 and MPEP. / Mathiesen, Jesper Mosolff; Svendsen, Nannette; Bräuner-Osborne, Hans; Thomsen, Christian; Ramirez, M Teresa.

    In: British Journal of Pharmacology, Vol. 138, No. 6, 03.2003, p. 1026-30.

    Research output: Research - peer-reviewJournal article

  9. Published

    Different domains of the glucagon and glucagon-like peptide-1 receptors provide the critical determinants of ligand selectivity. / Runge, S; Wulff, B S; Madsen, K; Bräuner-Osborne, Hans; Knudsen, L B.

    In: British Journal of Pharmacology, Vol. 138, No. 5, 03.2003, p. 787-94.

    Research output: Research - peer-reviewJournal article

  10. Published

    Three distinct epitopes on the extracellular face of the glucagon receptor determine specificity for the glucagon amino terminus. / Runge, Steffen; Gram, Christian; Bräuner-Osborne, Hans; Madsen, Kjeld; Knudsen, Lotte B; Wulff, Birgitte S.

    In: Journal of Biological Chemistry, Vol. 278, No. 30, 25.07.2003, p. 28005-10.

    Research output: Research - peer-reviewJournal article

  11. Published

    Synthesis and in vitro pharmacology at AMPA and kainate preferring glutamate receptors of 4-heteroarylmethylidene glutamate analogues. / Valgeirsson, Jon; Christensen, Jeppe K; Kristensen, Anders S; Pickering, Darryl S; Nielsen, Birgitte; Fischer, Christina; Bräuner-Osborne, Hans; Nielsen, Elsebet Ø; Krogsgaard-Larsen, Povl; Madsen, Ulf.

    In: Bioorganic & Medicinal Chemistry, Vol. 11, No. 20, 2003, p. 4341-9.

    Research output: Research - peer-reviewJournal article

ID: 1302910