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GPCRdb: an information system for G protein-coupled receptors

Publication: Research - peer-reviewJournal article

Standard

GPCRdb : an information system for G protein-coupled receptors. / Isberg, Vignir; Mordalski, Stefan; Munk, Christian; Rataj, Krzysztof; Harpsøe, Kasper; Hauser, Alexander S; Vroling, Bas; Bojarski, Andrzej J; Vriend, Gert; Gloriam, David E.

In: Nucleic acids research, Vol. 44, No. D1, 04.01.2016, p. D356-64.

Publication: Research - peer-reviewJournal article

Harvard

Isberg, V, Mordalski, S, Munk, C, Rataj, K, Harpsøe, K, Hauser, AS, Vroling, B, Bojarski, AJ, Vriend, G & Gloriam, DE 2016, 'GPCRdb: an information system for G protein-coupled receptors' Nucleic acids research, vol 44, no. D1, pp. D356-64. DOI: 10.1093/nar/gkv1178

APA

Isberg, V., Mordalski, S., Munk, C., Rataj, K., Harpsøe, K., Hauser, A. S., ... Gloriam, D. E. (2016). GPCRdb: an information system for G protein-coupled receptors. Nucleic acids research, 44(D1), D356-64. DOI: 10.1093/nar/gkv1178

Vancouver

Isberg V, Mordalski S, Munk C, Rataj K, Harpsøe K, Hauser AS et al. GPCRdb: an information system for G protein-coupled receptors. Nucleic acids research. 2016 Jan 4;44(D1):D356-64. Available from, DOI: 10.1093/nar/gkv1178

Author

Isberg, Vignir; Mordalski, Stefan; Munk, Christian; Rataj, Krzysztof; Harpsøe, Kasper; Hauser, Alexander S; Vroling, Bas; Bojarski, Andrzej J; Vriend, Gert; Gloriam, David E / GPCRdb : an information system for G protein-coupled receptors.

In: Nucleic acids research, Vol. 44, No. D1, 04.01.2016, p. D356-64.

Publication: Research - peer-reviewJournal article

Bibtex

@article{eb11b0ab1134400f849aaa11f5377b84,
title = "GPCRdb: an information system for G protein-coupled receptors",
abstract = "Recent developments in G protein-coupled receptor (GPCR) structural biology and pharmacology have greatly enhanced our knowledge of receptor structure-function relations, and have helped improve the scientific foundation for drug design studies. The GPCR database, GPCRdb, serves a dual role in disseminating and enabling new scientific developments by providing reference data, analysis tools and interactive diagrams. This paper highlights new features in the fifth major GPCRdb release: (i) GPCR crystal structure browsing, superposition and display of ligand interactions; (ii) direct deposition by users of point mutations and their effects on ligand binding; (iii) refined snake and helix box residue diagram looks; and (iii) phylogenetic trees with receptor classification colour schemes. Under the hood, the entire GPCRdb front- and back-ends have been re-coded within one infrastructure, ensuring a smooth browsing experience and development. GPCRdb is available at http://www.gpcrdb.org/ and it's open source code at https://bitbucket.org/gpcr/protwis.",
keywords = "Development of new medicine",
author = "Vignir Isberg and Stefan Mordalski and Christian Munk and Krzysztof Rataj and Kasper Harpsøe and Hauser, {Alexander S} and Bas Vroling and Bojarski, {Andrzej J} and Gert Vriend and Gloriam, {David E}",
note = "FUNDING: European Research Council [639125 to D.E.G]; Lundbeck Foundation [R163-2013-16327 to D.E.G]; Danish Council for Independent Research [1331-00180 to D.E.G]; Polish National Science Centre [DEC-2014/12/T/NZ2/00529 to S.M.]. Funding for open access charge: European Research Council [639125 to D.E.G].",
year = "2016",
month = "1",
doi = "10.1093/nar/gkv1178",
volume = "44",
pages = "D356--64",
journal = "Nucleic Acids Research",
issn = "0305-1048",
publisher = "Oxford University Press",
number = "D1",

}

RIS

TY - JOUR

T1 - GPCRdb

T2 - Nucleic Acids Research

AU - Isberg,Vignir

AU - Mordalski,Stefan

AU - Munk,Christian

AU - Rataj,Krzysztof

AU - Harpsøe,Kasper

AU - Hauser,Alexander S

AU - Vroling,Bas

AU - Bojarski,Andrzej J

AU - Vriend,Gert

AU - Gloriam,David E

N1 - FUNDING: European Research Council [639125 to D.E.G]; Lundbeck Foundation [R163-2013-16327 to D.E.G]; Danish Council for Independent Research [1331-00180 to D.E.G]; Polish National Science Centre [DEC-2014/12/T/NZ2/00529 to S.M.]. Funding for open access charge: European Research Council [639125 to D.E.G].

PY - 2016/1/4

Y1 - 2016/1/4

N2 - Recent developments in G protein-coupled receptor (GPCR) structural biology and pharmacology have greatly enhanced our knowledge of receptor structure-function relations, and have helped improve the scientific foundation for drug design studies. The GPCR database, GPCRdb, serves a dual role in disseminating and enabling new scientific developments by providing reference data, analysis tools and interactive diagrams. This paper highlights new features in the fifth major GPCRdb release: (i) GPCR crystal structure browsing, superposition and display of ligand interactions; (ii) direct deposition by users of point mutations and their effects on ligand binding; (iii) refined snake and helix box residue diagram looks; and (iii) phylogenetic trees with receptor classification colour schemes. Under the hood, the entire GPCRdb front- and back-ends have been re-coded within one infrastructure, ensuring a smooth browsing experience and development. GPCRdb is available at http://www.gpcrdb.org/ and it's open source code at https://bitbucket.org/gpcr/protwis.

AB - Recent developments in G protein-coupled receptor (GPCR) structural biology and pharmacology have greatly enhanced our knowledge of receptor structure-function relations, and have helped improve the scientific foundation for drug design studies. The GPCR database, GPCRdb, serves a dual role in disseminating and enabling new scientific developments by providing reference data, analysis tools and interactive diagrams. This paper highlights new features in the fifth major GPCRdb release: (i) GPCR crystal structure browsing, superposition and display of ligand interactions; (ii) direct deposition by users of point mutations and their effects on ligand binding; (iii) refined snake and helix box residue diagram looks; and (iii) phylogenetic trees with receptor classification colour schemes. Under the hood, the entire GPCRdb front- and back-ends have been re-coded within one infrastructure, ensuring a smooth browsing experience and development. GPCRdb is available at http://www.gpcrdb.org/ and it's open source code at https://bitbucket.org/gpcr/protwis.

KW - Development of new medicine

U2 - 10.1093/nar/gkv1178

DO - 10.1093/nar/gkv1178

M3 - Journal article

VL - 44

SP - D356-64

JO - Nucleic Acids Research

JF - Nucleic Acids Research

SN - 0305-1048

IS - D1

ER -

ID: 153606474