Employees – University of Copenhagen

Rasmus Prætorius Clausen

Rasmus Prætorius Clausen

Associate Professor

  • neuromedicinal chemistry
  • epigenetic medicinal chemistry
  • biostructure based SAR studies
  • peptide and protein based ligands
  • organic synthesis

Selected publications

  1. Published

    Subtype-Specific Agonists for NMDA Receptor Glycine Binding Sites

    Maolanon, A. R., Risgaard, R., Wang, S. Y., Snoep, Y., Papangelis, A., Yi, F., Holley, D., Barslund, A. F., Svenstrup, N., Hansen, K. B. & Clausen, R. P. 16 Aug 2017 In : ACS Chemical Neuroscience. 8, 8, p. 1681-1687 7 p.

    Research output: Contribution to journalLetter

  2. Published

    Tweaking subtype-selectivity and agonist efficacy at (S)-2-amino-3-(3-hydroxy-5-methyl-isoxazol-4-yl)propionic acid (AMPA) receptors in a small series of BnTetAMPA analogues

    Wang, S-Y., Larsen, Y., Navarrete, C. V., Jensen, A. A., Nielsen, B., Al-Musaed, A., Frydenvang, K., Kastrup, J. S., Pickering, D. S. & Clausen, R. P. 2016 In : Journal of Medicinal Chemistry. 59, 5, p. 2244-2254 11 p.

    Research output: Contribution to journalJournal article

  3. Published

    Substrate- and Cofactor-independent Inhibition of Histone Demethylase KDM4C

    Leurs, U., Lohse, B., Rand, K. D., Ming, S., Riise, E. S., Cole, P. A., Kristensen, J. L. & Clausen, R. P. 11 Jul 2014 In : A C S Chemical Biology. 9, 9, p. 2131-2138 8 p.

    Research output: Contribution to journalJournal article

  4. Published

    Targeting histone lysine demethylases by truncating the histone 3 tail to obtain selective substrate-based inhibitors

    Lohse, B., Nielsen, A. L., Kristensen, J. B. L., Helgstrand, C., Cloos, P. A. C., Olsen, L., Gajhede, M., Clausen, R. P. & Kristensen, J. L. 19 Sep 2011 In : Angewandte Chemie International Edition. 50, 39, p. 9100-9103

    Research output: Contribution to journalJournal article

  5. Published

    α4βδ GABA receptors are high-affinity targets for γ-hydroxybutyric acid (GHB)

    Absalom, N., Karim, N., Eghorn, L. F., Villumsen, I. S., Bay, T., Bräuner-Osborne, H., Frølund, B., Clausen, R. P., Olsen, J. V., Knudsen, G. M., Chebib, M. & Wellendorph, P. 14 Aug 2012 In : Proceedings of the National Academy of Sciences USA (PNAS). 109, 33, p. 13404-13409 6 p.

    Research output: Contribution to journalJournal article

ID: 1302218