Department of Drug Design and Pharmacology > Employees
Osman Asghar Mirza
30, Building: 311
2100 København Ø
Primary fields of research
We are interested in understanding the interplay between (un)natural compounds and secondary active transporters involved in health and disease. Our primary focus is on human intestinal transporters, which play important roles in nutrient and drug absorption. Furthermore, in cancers, expression of several of these transporters is upregulated due to high metabolic activity. Thus, molecular understanding of the structure and mechanism of these transporters may hold important clues towards improving both drug absorption and cancer therapy. Our experimental portfolio includes X-ray crystallography, functional assays, site-directed mutagenesis, biophysical analyses and bioinformatics.