Gloriam Group – University of Copenhagen

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Department of Drug Design and Pharmacology > Research > Biostructural Research > Gloriam Group

G Protein-Coupled Receptors -

GPCR Computational Drug Design Group

G Protein-Coupled Receptors

GPCRs constitute one of the largest human protein families. They are cell-surface receptors widely abundant in physiological systems and mediate the effect of ca 30% of marketed drugs. The Gloriam group studies receptor structures and functions of a number of GPCRs and applies computational methods to identify ligands:

  • Virtual Screening
  • Focused Compound Libraries
  • Bioinformatics & Chemoinformatics
  • Structure-based drug design
  • Web database / tool development

The group has a particular focus on the least characterised so called orphan receptors for which the endogenous ligands and functions are unknown. We also head GPCRdb, a community hub on the web for GPCR data, analysis tools and visualisation. Read more on the project pages below:

Core projects