Publication list – University of Copenhagen

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Department of Drug Design and Pharmacology > Research > Biostructural Research > Publications > Publication list

Biostructural Research

  1. 2018
  2. Published

    Human proton coupled folic acid transporter is a monodisperse oligomer in the lauryl maltose neopentyl glycol solubilized state. / Aduri, Nanda G; Ernst, Heidi A.; Prabhala, Bala K.; Bhatt, Shweta; Boesen, Thomas; Gajhede, Michael; Mirza, Osman.

    In: Biochemical and Biophysical Research Communications, Vol. 495, No. 2, 2018, p. 1738-1743.

    Research output: Research - peer-reviewJournal article

  3. Published

    Lysine demethylase inhibition protects pancreatic β cells from apoptosis and improves β-cell function. / Backe, Marie Balslev; Andersson, Jan Legaard; Bacos, Karl; Christensen, Dan Ploug; Hansen, Jakob Bondo; Dorosz, Jerzy Jòzef; Gajhede, Michael; Dahlby, Tina; Bysani, Madhusudhan; Kristensen, Line Hyltoft; Ling, Charlotte; Olsen, Lars; Mandrup-Poulsen, Thomas.

    In: Molecular and cellular endocrinology, Vol. 460, 15.01.2018, p. 47-56.

    Research output: Research - peer-reviewJournal article

  4. Accepted/In press

    7-Phenoxy-Substituted 3,4-Dihydro-2H-1,2,4-benzothiadiazine 1,1-Dioxides as Positive Allosteric Modulators of α-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid (AMPA) Receptors with Nanomolar Potency. / Goffin, Eric; Drapier, Thomas; Larsen, Anja Probst; Geubelle, Pierre; Ptak, Christopher P; Laulumaa, Saara; Rovinskaja, Karoline; Gilissen, Julie; Tullio, Pascal de; Olsen, Lars; Frydenvang, Karla; Pirotte, Bernard; Hanson, Julien; Oswald, Robert E; Kastrup, Jette Sandholm; Francotte, Pierre.

    In: Journal of medicinal chemistry, 2018.

    Research output: Research - peer-reviewJournal article

  5. Published

    Pharmacogenomics of GPCR Drug Targets. / Hauser, Alexander Sebastian; Chavali, Sreenivas; Masuho, Ikuo; Jahn, Leonie; Martemyanov, Kirill; Gloriam, David E.; Babu, Madan.

    In: Cell, 01.2018, p. 41-54 e19.

    Research output: Research - peer-reviewJournal article

  6. Published

    Structural Mapping of Adenosine Receptor Mutations : Ligand Binding and Signaling Mechanisms. / Jespers, Willem; Schiedel, Anke C; Heitman, Laura H; Cooke, Robert M; Kleene, Lisa; van Westen, Gerard J P; Gloriam, David E; Müller, Christa E; Sotelo, Eddy; Gutiérrez-de-Terán, Hugo.

    In: Trends in Pharmacological Sciences, Vol. 39, No. 1, 01.2018, p. 75-89.

    Research output: Research - peer-reviewReview

  7. Published

    Structural Basis of Histone Demethylase KDM6B Histone 3 Lysine 27 Specificity. / Jones, Sarah E; Olsen, Lars; Gajhede, Michael.

    In: Biochemistry, 2018.

    Research output: Research - peer-reviewJournal article

  8. E-pub ahead of print

    The prototypical proton-coupled oligopeptide transporter YdgR from Escherichia coli facilitates chloramphenicol uptake into bacterial cells. / Prabhala, Bala K; Aduri, Nanda G; Sharma, Neha; Shaheen, Aqsa; Sharma, Arpan; Iqbal, Mazhar; Hansen, Paul R; Brasen, Christoffer; Gajhede, Michael; Rahman, Moazur; Mirza, Osman.

    In: The Journal of biological chemistry, 2018.

    Research output: Research - peer-reviewJournal article

  9. 2017
  10. Published

    Higher-Order Structure in Bacterial VapBC Toxin-Antitoxin Complexes. / Bendtsen, Kirstine L; Brodersen, Ditlev E.

    Macromolecular Protein Complexes. Vol. 83 Springer, 2017. p. 381-412.

    Research output: ResearchBook chapter

  11. Published

    Dissecting the Cytochrome P450 1A2- and 3A4-Mediated Metabolism of Aflatoxin B1 in Ligand and Protein Contributions. / Bonomo, Silvia; Jørgensen, Flemming Steen; Olsen, Lars.

    In: Chemistry: A European Journal, Vol. 23, No. 12, 24.02.2017, p. 2884-2893.

    Research output: Research - peer-reviewJournal article

  12. Published

    Mechanism of Cytochrome P450 17A1-Catalyzed Hydroxylase and Lyase Reactions. / Bonomo, Silvia; Jørgensen, Flemming Steen; Olsen, Lars.

    In: Journal of chemical information and modeling, Vol. 57, No. 5, 22.05.2017, p. 1123-1133.

    Research output: Research - peer-reviewJournal article

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