Kristensen Group – University of Copenhagen

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Department of Drug Design and Pharmacology > Research > Medicinal Chemistry Research > Chemistry and Medicinal Chemistry > Kristensen Group

Kristensen Group

Kristensen Group

Medicinal Chemistry

   Neuroimaging    

The design and synthesis of new

ligands is at the core of our research

Development of new PET-ligands

towards different CNS targets

Research Focus

Generally medicinal chemistry and the development of new methodology for the construction of compound classes of relevance to medicinal chemistry. Using these tools we are trying to develop new probes and tools that will help us to elucidate the underlying mechanisms responsible for the regulation of different pharmacological targets: Ion channels, enzymes and GPCR’s.

Neuroimaging

We are developing new imaging agents

Erythrina Alkaloids

We are designing new ligands

based on natural products

5-HT2A Agonists

We are developing new selective

ligands for the Serotonie 2A receptor

Within the Marie Curie Training network SAFER

we are striving to develop new functionally

selective ligands for the Serotonine 2A receptor.

For more information see:

http://www.safer-itn.eu/

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Within the Horizon2020 project Click-It we are developing new imaging technology to improve clinical companion diagnostics for cancer patients.

For more information see:

http://click-it-imaging.eu/ 

Master projects

We offer a wide variety of different projects within the areas of organic/total synthesis, Medicinal Chemistry and Radiopharmaceuticals/PET-ligands. Please contact Jesper L. Kristensen for further info - we are always looking for new talent to join the group.

Examples of Recent Master projects

Emil Glibstrup: Synthetic strategies towards the CD-rings of DHBE.
Morten Borch: Synthesis and Biological Evaluation of Erythrina Alkaloid Analogues.
Ida Nymann Petersen: Total Synthesis of Pyridoacridines.
Sebastian Leth-Petersen: Synthetic tools for the study of consciousness.


Publications

Please see GoogleScholar or ResearchGate for an updated list of publications.