In our research, we study the cellular and molecular function of disease-relevant proteins in the brain, and identify new targets and therapeutic principles. We are particular interested in the molecular mechanisms behind synaptic transmission and the relation to physiology as well as disease. We apply a range of research techniques, such as electrophysiology on cells and slices, molecular biology methods, and pharmacological assays.
- We are interested in elucidating the neurobiology underlying arousal with the hope that we can identify targets for managing or restoring appropriate and adaptive levels of arousal associated with human behaviours.
Inhibitory Neurotransmission, Epilepsy, Electrophysiology, GABAA/C receptors, Kinetics of Ligand-Receptor Interaction, Receptor Selectivity by Kinetics.
- Our research focuses on brain functions that mediate stress and stress-related disorders, eg. depression. Moreover, we aim to assess novel targets and therapeutics for these afflictions.
- My laboratory focuses on understanding the molecular mechanisms and pharmacology of key proteins involved in synaptic transmission; specifically ligand-gated ion channels and neurotransmitter transporters.