Cell Signalling Pharmacology – University of Copenhagen

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Department of Drug Design and Pharmacology > Research > Molecular and Cellular Pharmacology > Cell Signalling Pharma...

Signals may arise inside cells in the absence of direct activation of a receptor. Also, signals elicited by activation of receptors may be either reinforced or curbed by interaction with other signalling pathways operating inside the cell. Thus, drugs acting solely on receptors are not able to modify such signals. 

However, activation of receptors on the surface of cells remain the largest single group of targets for currently marketed drugs.

In the Cell Signalling Pharmacology Lab, we aim to better understand receptor- and non receptor-mediated 3’,5’-cyclic adenosine monophosphate (cAMP) signals, how these interact with concurrent Ca2+ signals, and which cellular functions are under the control of these signals.

We believe that knowledge about these intersecting signals is necessary for developing novel strategies to treat a range of diseases with an unmet need for novel pharmacology.

Research interests & more