Patient-Oriented Pharmaceutics can be defined as a field which on both a scientific and a practical level deals with pharmaceutical activities to ensure rational pharmacotherapy for both patients and society.
Thus research within Patient-Oriented Pharmaceutics aims at providing optimal and safe drug treatment for the individual patient. One goal is to elucidate the influence of dosage forms and administration routes on the pharmacokinetic and pharmacodynamics behaviour and the final impact of both wanted effects and the side-effects, other goals are to develop procedures for quality assurance in medication processes in the clinical setting in order to ensure a cost-effective treatment and to improve methodology of clinical drug research in order to guarantee that the results reflects the actual pharmacological effectiveness.
Most of the recent projects are within translational pain research and intensive care and are integrated with the projects carried out in the pharmacometrics group.
Within translational pain research focus is on elucidating individual variations in responsiveness to opioids and adjuvant analgesics and to study the balance between analgesia and side effects in order to be able to tailor an optimal balance between pain relief and unacceptable side-effects for the individual patient. Projects include both cancer, chronic and acute pain conditions and experimentally induced pain.
Within intensive care projects are focused on optimising the procedures on antibiotic therapy by implementing Therapeutic Drug Monitoring (TDM); the goal being to ensure sufficient dosage, avoidance of toxicity and development of drug resistance.
We currently have collaborations with:
- Department of Pharmacology, University of Adelaide
- Mech-Sense Center, Aalborg Hospital
- Department of Anaesthesia, Rigshospitalet
- Department of Pediatrics and Adolescents Medicine, Rigshospitalet
- Department of Diagnostic Radiology, Herlev Hospital
- Intensive Care Unit, Rigshospitalet
- Section of Palliative Care, Rigshospitalet
- Multidisciplinary Pain Centre, Rigshospitalet
- Multidisciplinary Pain Centre, Køge Hospital
- Capital Region Hospital Pharmacy
- SAFE – Hospital Pharmacies Research Unit
- Quality and Development, Zealand Region
Furthermore, we aim at close integration of our academic research with the pharmaceutical industry, where we have collaborations with: