Biopharmaceuticals

 

 

 

  • Rearrangement of Thiodepsipeptides by S–N Acyl Shift Delivers Homodetic Autoinducing Peptides” J. Am. Chem. Soc. 2021
  • “Targeting the APP-Mint2 protein-protein interaction with a peptide based-inhibitor reduces amyloid-β formation” J. Am. Chem. Soc. 2021

  • “Hydroxamic acid-modified peptide microarrays for profiling isozyme-selective interactions and inhibition of histone deacetylases” Nat. Commun. 2021

  • ”Insertion of synthetic peptides into proteins by tandem protein trans-splicing” Nat. Commun. 2020

  • ”Structure of the human sodium leak channel” Nature 2020

  • “Targeting receptor complexes: A new dimension in drug discovery” Nat. Rev. Drug Discov. 2020

  • “Mechanism and site of action of big dynorphin on ASIC1a” Proc. Natl. Acad. Sci. U.S.A. 2020

  • “A high-affinity, bivalent PDZ domain inhibitor complexes PICK1 to alleviate neuropathic pain” EMBO Mol. Med.  2020

  • “Peptide inhibitors of the α-cobratoxin–nicotinic acetylcholine receptor interaction” J. Med. Chem. 2020

  • “Molecular architecture of the Jumonji C family histone demethylase KDM5B” Sci. Rep. 2019

  • “De novo macrocyclic peptides that specifically modulate Lys48-linked ubiquitin chains” Nat. Chem. 2019

  • “Identification of autoinducing thiodepsipeptides from staphylococci enabled by native chemical ligation” Nat. Chem. 2019

  • “Arylfluorosulfate-based electrophiles for covalent protein labeling: a new addition to the arsenal” Angew. Chem. Int. Ed. 2019

 

 

 

 

 

 

 

  

portrait

Cluster Leader

Christian Adam Olsen
Professor
cao@sund.ku.dk

Communications representativ

Communications Representative

Joseph Rogers
Associate Professor
joseph.rogers@sund.ku.dk