Biopharmaceuticals

 

 

 

  • Rearrangement of Thiodepsipeptides by S–N Acyl Shift Delivers Homodetic Autoinducing Peptides” J. Am. Chem. Soc. 2021
  • “Targeting the APP-Mint2 protein-protein interaction with a peptide based-inhibitor reduces amyloid-β formation” J. Am. Chem. Soc. 2021

  • “Hydroxamic acid-modified peptide microarrays for profiling isozyme-selective interactions and inhibition of histone deacetylases” Nat. Commun. 2021

  • ”Insertion of synthetic peptides into proteins by tandem protein trans-splicing” Nat. Commun. 2020

  • ”Structure of the human sodium leak channel” Nature 2020

  • “Targeting receptor complexes: A new dimension in drug discovery” Nat. Rev. Drug Discov. 2020

  • “Mechanism and site of action of big dynorphin on ASIC1a” Proc. Natl. Acad. Sci. U.S.A. 2020

  • “A high-affinity, bivalent PDZ domain inhibitor complexes PICK1 to alleviate neuropathic pain” EMBO Mol. Med.  2020

  • “Peptide inhibitors of the α-cobratoxin–nicotinic acetylcholine receptor interaction” J. Med. Chem. 2020

  • “Molecular architecture of the Jumonji C family histone demethylase KDM5B” Sci. Rep. 2019

  • “De novo macrocyclic peptides that specifically modulate Lys48-linked ubiquitin chains” Nat. Chem. 2019

  • “Identification of autoinducing thiodepsipeptides from staphylococci enabled by native chemical ligation” Nat. Chem. 2019

  • “Arylfluorosulfate-based electrophiles for covalent protein labeling: a new addition to the arsenal” Angew. Chem. Int. Ed. 2019

 

 

 

 

 

 

 

  

portrait

Cluster Leader

Christian Adam Olsen
Professor
cao@sund.ku.dk

Communications representativ

Communications Representative

Joseph Rogers
Associate Professor
joseph.rogers@sund.ku.dk

Core members

Name Title Image
Christian Adam Olsen Professor Billede af Christian Adam Olsen
Joseph Matthew Rogers Associate Professor Billede af Joseph Matthew Rogers
Kristian Strømgaard Professor Billede af Kristian Strømgaard
Mette Homann Poulsen Assistant Professor Billede af Mette Homann Poulsen
Michael Gajhede Professor Billede af Michael Gajhede
Stephan Pless Professor Billede af Stephan Pless
Stephanie Heusser Assistant Professor Billede af Stephanie Heusser
Vita Sereikaité Assistant Professor Billede af Vita Sereikaité