Biopharmaceuticals

• Rearrangement of Thiodepsipeptides by S–N Acyl Shift Delivers Homodetic Autoinducing Peptides” J. Am. Chem. Soc. 2021
• “Targeting the APP-Mint2 protein-protein interaction with a peptide based-inhibitor reduces amyloid-β formation” J. Am. Chem. Soc. 2021
  
  
• “Hydroxamic acid-modified peptide microarrays for profiling isozyme-selective interactions and inhibition of histone deacetylases” Nat. Commun. 2021
  
  
• ”Insertion of synthetic peptides into proteins by tandem protein trans-splicing” Nat. Commun. 2020
  
  
• ”Structure of the human sodium leak channel” Nature 2020
  
  
• “Targeting receptor complexes: A new dimension in drug discovery” Nat. Rev. Drug Discov. 2020
  
  
• “Mechanism and site of action of big dynorphin on ASIC1a” Proc. Natl. Acad. Sci. U.S.A. 2020
  
  
• “A high-affinity, bivalent PDZ domain inhibitor complexes PICK1 to alleviate neuropathic pain” EMBO Mol. Med.  2020
  
  
• “Peptide inhibitors of the α-cobratoxin–nicotinic acetylcholine receptor interaction” J. Med. Chem. 2020
  
  
• “Molecular architecture of the Jumonji C family histone demethylase KDM5B” Sci. Rep. 2019
  
  
• “De novo macrocyclic peptides that specifically modulate Lys48-linked ubiquitin chains” Nat. Chem. 2019
  
  
• “Identification of autoinducing thiodepsipeptides from staphylococci enabled by native chemical ligation” Nat. Chem. 2019
  
  
• “Arylfluorosulfate-based electrophiles for covalent protein labeling: a new addition to the arsenal” Angew. Chem. Int. Ed. 2019

Christian Adam Olsen
Joseph Rogers
Kristian Strømgaard
Michael Gajhede
Stephan Pless