Thor Seneca Thorsen

Thor Seneca Thorsen

Assistant professor


  1. 2021
  2. Published

    Binding of a negative allosteric modulator and competitive antagonist can occur simultaneously at the ionotropic glutamate receptor GluA2

    Krintel, C., Dorosz, J., Larsen, A. H., Thorsen, Thor Seneca, Venskutonytė, R., Mirza, Osman Asghar, Gajhede, Michael, Boesen, T. & Kastrup, Jette Sandholm Jensen, 2021, In: The FEBS Journal. 288, p. 995-1007 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. 2019
  4. Published

    Mechanisms of PDZ domain scaffold assembly illuminated by use of supported cell membrane sheets

    Erlendsson, Simon, Thorsen, Thor Seneca, Vauquelin, G., Ammendrup-Johnsen, I., Wirth, V., Martinez, Karen Laurence, Teilum, Kaare, Gether, Ulrik & Madsen, Kenneth Lindegaard, 2019, In: eLife. 8, p. 1-27 e39180.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Supported Cell Membrane Sheets to Monitor Protein Assembly

    Erlendsson, Simon, Thorsen, Thor Seneca & Madsen, Kenneth Lindegaard, 2019, In: Bio-protocol. 9, 18

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. 2018
  7. Published

    Small-angle neutron scattering studies on the AMPA receptor GluA2 in the resting, AMPA-bound and GYKI-53655-bound states

    Larsen, A. H., Dorosz, J., Thorsen, Thor Seneca, Johansen, Nicolai Tidemand, Darwish, T., Midtgaard, S. R., Arleth, Lise & Kastrup, Jette Sandholm Jensen, Nov 2018, In: IUCrJ. 5, p. 780-793

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Invisible detergents for structure determination of membrane proteins by small-angle neutron scattering

    Midtgaard, S. R., Darwish, T. A., Pedersen, M. C., Huda, P., Larsen, A. H., Jensen, G. V., Kynde, S. A. R., Skar-Gislinge, N., Nielsen, A. J. Z., Olesen, C., Blaise, M., Dorosz, J. J., Thorsen, Thor Seneca, Venskutonytė, R., Krintel, C., Møller, J. V., Frielinghaus, H., Gilbert, E. P., Martel, A., Kastrup, Jette Sandholm Jensen, Jensen, P. E., Nissen, P. & Arleth, Lise, Jan 2018, In: F E B S Journal. 285, 2, p. 357-371 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. 2017
  10. Published

    Structure and affinity of two bicyclic glutamate analogues at AMPA and kainate receptors

    Møllerud, S., Pinto, A., Marconi, L., Frydenvang, Karla Andrea, Thorsen, Thor Seneca, Laulumaa, S. K., Venskutonyte, R., Winther, Nikolaj Sebastian, Cunado Moral, A. M., Tamborini, L., Conti, P., Pickering, Darryl S & Kastrup, Jette Sandholm Jensen, 2017, In: A C S Chemical Neuroscience. 8, 9, p. 2056-2064 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. 2015
  12. Published

    Structure of dimeric and tetrameric complexes of the BAR domain protein PICK1 determined by small-angle X-Ray scattering

    Karlsen, M. L., Thorsen, Thor Seneca, Johner, N., Ammendrup-Johnsen, I., Erlendsson, Simon, Tian, X., Simonsen, J. B., Hoiberg-Nielsen, R., Christensen, N. M., Khelashvili, G., Streicher, W., Teilum, Kaare, Vestergaard, Bente, Weinstein, H., Gether, Ulrik, Arleth, Lise & Madsen, Kenneth Lindegaard, 7 Jul 2015, In: Structure. 23, 7, p. 1258-1270 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. 2012
  14. Published

    Protein interacting with C kinase 1 (PICK1) reduces reinsertion rates of interaction partners sorted to Rab11-dependent slow recycling pathway

    Madsen, Kenneth Lindegaard, Thorsen, Thor Seneca, Rahbek-Clemmensen, T., Eriksen, J. M. & Gether, Ulrik, 6 Apr 2012, In: The Journal of Biological Chemistry. 287, 15, p. 12293-308 16 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Serine 77 in the PDZ domain of PICK1 is a protein kinase Cα phosphorylation site regulated by lipid membrane binding

    Ammendrup-Johnsen, I., Thorsen, Thor Seneca, Gether, Ulrik & Madsen, Kenneth Lindegaard, 17 Jan 2012, In: Biochemistry. 51, 2, p. 586-96 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. 2011
  17. Published

    A fluorescence polarization based screening assay for identification of small molecule inhibitors of the PICK1 PDZ domain

    Thorsen, Thor Seneca, Madsen, Kenneth Lindegaard, Dyhring, T., Bach, Anders, Peters, D., Strømgaard, Kristian, Rønn, L. C. B. & Gether, Ulrik, 1 Aug 2011, In: Combinatorial Chemistry & High Throughput Screening. 14, 7, p. 590-600 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

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