GPCRdb database

GPCRdb

GPCRdb serves over 3000 researchers every month. GPCRdb features reference data, web tools and visualisation diagrams enabling science in the wider GPCR community. It also holds web-based tools to design new experiments - a mutation design tool for ligand binding sites and a construct design tool for structure determination.

More information
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NC-IUPHAR newsletter (pages 3-4)
GPCRdb poster
Popular scientific article (in Danish)

Selected Publications
GPCRdb in 2018: Adding GPCR structure models and ligands
Pándy-Szekeres G, Munk C, Tsonkov T, Mordalski S, Harpsøe K, Hauser AS, Bojarski AJ and Gloriam DE
Nucleic Acids Research. 2017

Munk C, Harpsøe H, Hauser A, Isberg V, and Gloriam DE
Integrating structural and mutagenesis data to elucidate GPCR ligand binding.
Curr Opin Pharmacol, 2016 Jul 28;30:51-58

Munk C, Isberg V, Mordalski S, Harpsøe K, Rataj K, Hauser A, Kolb P, Bojarski AJ, Vriend G, and Gloriam DE
GPCRdb: The G protein-coupled receptor database - An introduction.
Br J Pharmacol, 2016 Jul;173(14):2195-207

Isberg V, Mordalski S, Munk C, Rataj K, Harpsøe K, Hauser AS, Vroling B, Bojarski AJ, Vriend G, and Gloriam DE
GPCRdb: an information system for G protein-coupled receptors
Nucleic Acids Res, 2016 Jan 4;44(D1):D356-64

Isberg V, de Graaf C, Bortolato A, Cherezov V, Katritch V, Marshall FH, Mordalski S, Pin JP, Stevens RC, Vriend G, Gloriam DE.
Generic GPCR residue numbers - aligning topology maps while minding the gaps.
Trends Pharmacol Sci.  2015 Jan;36(1):22-31.; PMID: 25541108

Isberg V, Vroling B, van der Kant R, Li K, Vriend G and Gloriam DE
GPCRDB: information system for G protein-coupled receptors
Nucleic Acids Res. 2014 Jan 1;42(1); PMID: 24304901