Albert Jelke Kooistra

Albert Jelke Kooistra

Assistant professor

Member of:


    1. 2016
    2. Identification of Ligand Binding Hot Spots of the Histamine H1 Receptor following Structure-Based Fragment Optimization. / Kuhne, Sebastiaan; Kooistra, Albert J.; Bosma, Reggie; Bortolato, Andrea; Wijtmans, Maikel; Vischer, Henry F.; Mason, Jonathan S.; De Graaf, Chris; De Esch, Iwan J.P.; Leurs, Rob.

      In: Journal of Medicinal Chemistry, Vol. 59, No. 19, 13.10.2016, p. 9047-9061.

      Research output: Contribution to journalJournal articleResearchpeer-review

    3. Molecular interaction fingerprint approaches for GPCR drug discovery. / Vass, Márton; Kooistra, Albert J.; Ritschel, Tina; Leurs, Rob; de Esch, Iwan JP; de Graaf, Chris.

      In: Current Opinion in Pharmacology, Vol. 30, 01.10.2016, p. 59-68.

      Research output: Contribution to journalReviewResearchpeer-review

    4. PDEStrIAn : A Phosphodiesterase Structure and Ligand Interaction Annotated Database As a Tool for Structure-Based Drug Design. / Jansen, Chimed; Kooistra, Albert J.; Kanev, Georgi K.; Leurs, Rob; De Esch, Iwan J.P.; De Graaf, Chris.

      In: Journal of Medicinal Chemistry, Vol. 59, No. 15, 11.08.2016, p. 7029-7065.

      Research output: Contribution to journalReviewResearchpeer-review

    5. Function-specific virtual screening for GPCR ligands using a combined scoring method. / Kooistra, Albert J.; Vischer, Henry F.; McNaught-Flores, Daniel; Leurs, Rob; De Esch, Iwan J.P.; De Graaf, Chris.

      In: Scientific Reports, Vol. 6, 28288, 24.06.2016.

      Research output: Contribution to journalJournal articleResearchpeer-review

    6. KLIFS : A structural kinase-ligand interaction database. / Kooistra, Albert J.; Kanev, Georgi K.; Van Linden, Oscar P.J.; Leurs, Rob; De Esch, Iwan J.P.; De Graaf, Chris.

      In: Nucleic Acids Research, Vol. 44, No. D1, 01.01.2016, p. D365-D371.

      Research output: Contribution to journalJournal articleResearchpeer-review

    7. 2015
    8. Structure-based virtual screening for fragment-like ligands of the G protein-coupled histamine H4 receptor. / Istyastono, Enade P.; Istyastono, Enade P.; Kooistra, Albert J.; Vischer, Henry F.; Kuijer, Martien; Roumen, Luc; Nijmeijer, Saskia; Smits, Rogier A.; De Esch, Iwan J.P.; Leurs, Rob; De Graaf, Chris.

      In: MedChemComm, Vol. 6, No. 6, 01.06.2015, p. 1003-1017.

      Research output: Contribution to journalJournal articleResearchpeer-review

    9. Combinatorial consensus scoring for ligand-based virtual fragment screening : A comparative case study for serotonin 5-HT3A, histamine H1, and Histamine H4 receptors. / Schultes, Sabine; Kooistra, Albert J.; Vischer, Henry F.; Nijmeijer, Saskia; Haaksma, Eric E.J.; Leurs, Rob; De Esch, Iwan J.P.; De Graaf, Chris.

      In: Journal of Chemical Information and Modeling, Vol. 55, No. 5, 26.05.2015, p. 1030-1034.

      Research output: Contribution to journalJournal articleResearchpeer-review

    10. Structure-based prediction of g-protein-coupled receptor ligand function : A β-adrenoceptor case study. / Kooistra, Albert J.; Leurs, Rob; De Esch, Iwan J.P.; De Graaf, Chris.

      In: Journal of Chemical Information and Modeling, Vol. 55, No. 5, 26.05.2015, p. 1045-1061.

      Research output: Contribution to journalJournal articleResearchpeer-review

    11. The viral G protein-coupled receptor ORF74 hijacks β-arrestins for endocytic trafficking in response to human chemokines. / De Munnik, Sabrina M.; Kooistra, Albert J.; Van Offenbeek, Jody; Nijmeijer, Saskia; De Graaf, Chris; Smit, Martine J.; Leurs, Rob; Vischer, Henry F.

      In: PLOS ONE, Vol. 10, No. 4, e0124486, 20.04.2015.

      Research output: Contribution to journalJournal articleResearchpeer-review

    12. Analyzing multitarget activity landscapes using protein-ligand interaction fingerprints : Interaction cliffs. / Méndez-Lucio, Oscar; Kooistra, Albert J.; Graaf, Chris De; Bender, Andreas; Medina-Franco, José L.

      In: Journal of Chemical Information and Modeling, Vol. 55, No. 2, 23.02.2015, p. 251-262.

      Research output: Contribution to journalJournal articleResearchpeer-review

    ID: 196033213