Alexander Sebastian Hauser
Alexander Sebastian Hauser

Postdoc


  1. 2020
  2. Published

    Novel approaches leading towards peptide GPCR de-orphanisation

    Hauser, Alexander Sebastian, Gloriam, David E., Bräuner-Osborne, Hans & Foster, S. R., 1 Mar 2020, In : British Journal of Pharmacology. 177, 5, p. 961-968 8 p.

    Research output: Contribution to journalReviewResearchpeer-review

  3. 2019
  4. Published

    Discovery of Human Signaling Systems: Pairing Peptides to G Protein-Coupled Receptors

    Foster, S. R., Hauser, Alexander Sebastian, Vedel, Line, Strachan, R. T., Huang, X., Gavin, A. C., Shah, S. D., Nayak, A. P., Haugaard-Kedström, L. M., Penn, R. B., Roth, B. L., Bräuner-Osborne, Hans & Gloriam, David E., 31 Oct 2019, In : Cell. 179, 4, p. 895-908

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Receptor selectivity between the G proteins Gα 12 and Gα 13 is defined by a single leucine-to-isoleucine variation

    Mackenzie, A. E., Quon, T., Lin, L. C., Hauser, Alexander Sebastian, Jenkins, L., Inoue, A., Tobin, A. B., Gloriam, David E., Hudson, B. D. & Milligan, G., 1 Apr 2019, In : FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 33, 4, p. 5005-5017 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. 2018
  7. Published

    Pharmacogenomics of GPCR Drug Targets

    Hauser, Alexander Sebastian, Chavali, S., Masuho, I., Jahn, L., Martemyanov, K., Gloriam, David E. & Babu, M., Jan 2018, In : Cell. 172, p. 41–54

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    GPCRdb in 2018: adding GPCR structure models and ligands

    Pándy-Szekeres, G., Munk, Christian, Tsonkov, T. M., Mordalski, Stefan Mateusz, Harpsøe, Kasper, Hauser, Alexander Sebastian, Bojarski, A. J. & Gloriam, David E., 2018, In : Nucleic Acids Research. 46, D1, 7 p., gkx1109.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. 2017
  10. Published

    Trade-off between GPCR folding and functional versatility

    Prado, D. E., Flock, T., Hauser, Alexander Sebastian, Hegde, R. S. & Babu, M. M., Dec 2017, In : Protein Science. 26, p. 135-136

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  11. Published

    Trends in GPCR drug discovery: new agents, targets and indications

    Hauser, Alexander Sebastian, Gloriam, David E., Attwood, M. M., Rask-Andersen, M. & Schiöth, H. B., 27 Oct 2017, In : Nature Reviews. Drug Discovery. 16, p. 829-842 14 p., 178.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Identification of Histamine H3 Receptor Ligands Using a New Crystal Structure Fragment-based Method

    Frandsen, I. O., Boesgaard, Michael Worch, Fidom, K., Hauser, Alexander Sebastian, Isberg, V., Bräuner-Osborne, Hans, Wellendorph, Petrine & Gloriam, David E., 6 Jul 2017, In : Scientific Reports. 7, 1, 10 p., 4829.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Selectivity determinants of GPCR-G-protein binding

    Flock, T., Hauser, Alexander Sebastian, Lund, N., Gloriam, David E., Balaji, S. & Babu, M. M., 18 May 2017, In : Nature. 545, 7654, p. 317-322 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    The orphan G protein-coupled receptor GPR139 is activated by the peptides: Adrenocorticotropic hormone (ACTH), α-, and β-melanocyte stimulating hormone (α-MSH, and β-MSH), and the conserved core motif HFRW

    Jensen, A. C. N., Shehata, Mohamed A., Hauser, Alexander Sebastian, Isberg, V., Mokrosinski, J., Farooqi, I. S., Pedersen, D. S., Gloriam, David E. & Bräuner-Osborne, Hans, 1 Jan 2017, In : Neurochemistry International. 102, p. 105-113

    Research output: Contribution to journalJournal articleResearchpeer-review

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