Alexander Sebastian Hauser

Alexander Sebastian Hauser

Postdoc


Publication year:
  1. Published

    A new crystal structure fragment-based pharmacophore method for G protein-coupled receptors. / Fidom, Kimberley; Isberg, Vignir; Hauser, Alexander Sebastian; Mordalski, Stefan; Lehto, Thomas; Bojarski, Andrzej J; Gloriam, David E.

    In: Methods, Vol. 71, 01.2015, p. 104-112.

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Published

    Selectivity determinants of GPCR-G-protein binding. / Flock, Tilman; Hauser, Alexander S; Lund, Nadia; Gloriam, David E; Balaji, Santhanam; Babu, M Madan.

    In: Nature, Vol. 545, No. 7654, 18.05.2017, p. 317-322.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Discovery of Human Signaling Systems : Pairing Peptides to G Protein-Coupled Receptors. / Foster, Simon R; Hauser, Alexander S; Vedel, Line; Strachan, Ryan T; Huang, Xi-Ping; Gavin, Ariana C; Shah, Sushrut D; Nayak, Ajay P; Haugaard-Kedström, Linda M; Penn, Raymond B; Roth, Bryan L; Bräuner-Osborne, Hans; Gloriam, David E.

    In: Cell, Vol. 179, No. 4, 31.10.2019, p. 895-908.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Identification of Histamine H3 Receptor Ligands Using a New Crystal Structure Fragment-based Method. / Frandsen, Ida Osborn; Boesgaard, Michael W; Fidom, Kimberley; Hauser, Alexander S; Isberg, Vignir; Bräuner-Osborne, Hans; Wellendorph, Petrine; Gloriam, David E.

    In: Scientific Reports, Vol. 7, No. 1, 4829, 06.07.2017.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Pharmacogenomics of GPCR Drug Targets. / Hauser, Alexander Sebastian; Chavali, Sreenivas; Masuho, Ikuo; Jahn, Leonie; Martemyanov, Kirill; Gloriam, David E.; Babu, Madan.

    In: Cell, Vol. 172, 01.2018, p. 41–54.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Investigations and design of pyridine-2-carboxylic acid thiazol-2-ylamide analogs as methionine aminopeptidase inhibitors using 3D-QSAR and molecular docking. / Hauser, Alexander Sebastian.

    In: Medicinal Chemistry Research, Vol. 23, No. 8, 01.08.2014, p. 3861.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. LEADS-PEP : A Benchmark Data Set for Assessment of Peptide Docking Performance. / Hauser, Alexander Sebastian; Windshügel, Björn.

    In: Journal of Chemical Information and Modeling, Vol. 56, No. 1, 11.01.2016, p. 188-200.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Trends in GPCR drug discovery: new agents, targets and indications. / Hauser, Alexander Sebastian; Gloriam, David E.; Attwood, Misty M.; Rask-Andersen, Mathias ; Schiöth, Helgi B. .

    In: Nature Reviews. Drug Discovery, Vol. 16, 178, 27.10.2017, p. 829-842.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    GPCRdb : an information system for G protein-coupled receptors. / Isberg, Vignir; Mordalski, Stefan; Munk, Christian; Rataj, Krzysztof; Harpsøe, Kasper; Hauser, Alexander S; Vroling, Bas; Bojarski, Andrzej J; Vriend, Gert; Gloriam, David E.

    In: Nucleic Acids Research, Vol. 44, No. D1, 04.01.2016, p. D356-64.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    The orphan G protein-coupled receptor GPR139 is activated by the peptides : Adrenocorticotropic hormone (ACTH), α-, and β-melanocyte stimulating hormone (α-MSH, and β-MSH), and the conserved core motif HFRW. / Jensen, Anne Cathrine Nøhr; Shehata, Mohamed A; Hauser, Alexander S; Isberg, Vignir; Mokrosinski, Jacek; Farooqi, I Sadaf; Pedersen, Daniel Sejer; Gloriam, David E; Bräuner-Osborne, Hans.

    In: Neurochemistry International, Vol. 102, 01.01.2017, p. 105-113.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Receptor selectivity between the G proteins Gα 12 and Gα 13 is defined by a single leucine-to-isoleucine variation. / Mackenzie, Amanda E.; Quon, Tezz; Lin, Li Chiung; Hauser, Alexander S.; Jenkins, Laura; Inoue, Asuka; Tobin, Andrew B.; Gloriam, David E.; Hudson, Brian D.; Milligan, Graeme.

    In: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 33, No. 4, 01.04.2019, p. 5005-5017.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    GPCRdb: The G protein-coupled receptor database - an introduction. / Munk, C; Isberg, V; Mordalski, S; Harpsøe, K; Rataj, K; Hauser, A S; Kolb, P; Bojarski, A J; Vriend, G; Gloriam, D E.

    In: British Journal of Pharmacology, Vol. 173, No. 14, 07.2016, p. 2195-207.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Integrating structural and mutagenesis data to elucidate GPCR ligand binding. / Munk, Christian; Harpsøe, Kasper; Hauser, Alexander S; Isberg, Vignir; Gloriam, David E.

    In: Current Opinion in Pharmacology, Vol. 30, 10.2016, p. 51-58.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Trade-off between GPCR folding and functional versatility. / Prado, Daniel Estevez; Flock, Tilman; Hauser, Alexander S.; Hegde, Ramanujan S.; Babu, M. Madan.

    In: Protein Science, Vol. 26, 12.2017, p. 135-136.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  15. Published

    GPCRdb in 2018 : adding GPCR structure models and ligands. / Pándy-Szekeres, Gáspár; Munk, Christian; Tsonkov, Tsonko M; Mordalski, Stefan; Harpsøe, Kasper; Hauser, Alexander S; Bojarski, Andrzej J; Gloriam, David E.

    In: Nucleic Acids Research, Vol. 46, No. D1, gkx1109, 2018.

    Research output: Contribution to journalJournal articleResearchpeer-review

ID: 143688078