Alexander Sebastian Hauser
Alexander Sebastian Hauser

Postdoc


Publication year:
  1. Published

    A new crystal structure fragment-based pharmacophore method for G protein-coupled receptors

    Fidom, K., Isberg, V., Hauser, Alexander Sebastian, Mordalski, S., Lehto, T., Bojarski, A. J. & Gloriam, David E., Jan 2015, In : Methods. 71, p. 104-112 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Published

    Selectivity determinants of GPCR-G-protein binding

    Flock, T., Hauser, Alexander Sebastian, Lund, N., Gloriam, David E., Balaji, S. & Babu, M. M., 18 May 2017, In : Nature. 545, 7654, p. 317-322 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Discovery of Human Signaling Systems: Pairing Peptides to G Protein-Coupled Receptors

    Foster, S. R., Hauser, Alexander Sebastian, Vedel, Line, Strachan, R. T., Huang, X., Gavin, A. C., Shah, S. D., Nayak, A. P., Haugaard-Kedström, L. M., Penn, R. B., Roth, B. L., Bräuner-Osborne, Hans & Gloriam, David E., 31 Oct 2019, In : Cell. 179, 4, p. 895-908

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Identification of Histamine H3 Receptor Ligands Using a New Crystal Structure Fragment-based Method

    Frandsen, I. O., Boesgaard, Michael Worch, Fidom, K., Hauser, Alexander Sebastian, Isberg, V., Bräuner-Osborne, Hans, Wellendorph, Petrine & Gloriam, David E., 6 Jul 2017, In : Scientific Reports. 7, 1, 10 p., 4829.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Trends in GPCR drug discovery: new agents, targets and indications

    Hauser, Alexander Sebastian, Gloriam, David E., Attwood, M. M., Rask-Andersen, M. & Schiöth, H. B., 27 Oct 2017, In : Nature Reviews. Drug Discovery. 16, p. 829-842 14 p., 178.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Investigations and design of pyridine-2-carboxylic acid thiazol-2-ylamide analogs as methionine aminopeptidase inhibitors using 3D-QSAR and molecular docking

    Hauser, Alexander Sebastian, 1 Aug 2014, In : Medicinal Chemistry Research. 23, 8, p. 3861 3875 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. LEADS-PEP: A Benchmark Data Set for Assessment of Peptide Docking Performance

    Hauser, Alexander Sebastian & Windshügel, B., 11 Jan 2016, In : Journal of Chemical Information and Modeling. 56, 1, p. 188-200 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Pharmacogenomics of GPCR Drug Targets

    Hauser, Alexander Sebastian, Chavali, S., Masuho, I., Jahn, L., Martemyanov, K., Gloriam, David E. & Babu, M., Jan 2018, In : Cell. 172, p. 41–54

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    GPCRdb: an information system for G protein-coupled receptors

    Isberg, V., Mordalski, S., Munk, Christian, Rataj, K., Harpsøe, Kasper, Hauser, Alexander Sebastian, Vroling, B., Bojarski, A. J., Vriend, G. & Gloriam, David E., 4 Jan 2016, In : Nucleic Acids Research. 44, D1, p. D356-64

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    The orphan G protein-coupled receptor GPR139 is activated by the peptides: Adrenocorticotropic hormone (ACTH), α-, and β-melanocyte stimulating hormone (α-MSH, and β-MSH), and the conserved core motif HFRW

    Jensen, A. C. N., Shehata, Mohamed A., Hauser, Alexander Sebastian, Isberg, V., Mokrosinski, J., Farooqi, I. S., Pedersen, D. S., Gloriam, David E. & Bräuner-Osborne, Hans, 1 Jan 2017, In : Neurochemistry International. 102, p. 105-113

    Research output: Contribution to journalJournal articleResearchpeer-review

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