Anders Bach

Anders Bach

Associate Professor


  1. 2019
  2. Published

    Selectivity, efficacy and toxicity studies of UCCB01-144, a dimeric neuroprotective PSD-95 inhibitor. / Bach, Anders; Clausen, Bettina H; Kristensen, Lotte K; Andersen, Maria G; Ellman, Ditte Gry; Hansen, Pernille B L; Hasseldam, Henrik; Heitz, Marc; Özcelik, Dennis; Tuck, Ellie J; Kopanitsa, Maksym V; Grant, Seth G N; Lykke-Hartmann, Karin; Johansen, Flemming F; Lambertsen, Kate L; Strømgaard, Kristian.

    In: Neuropharmacology, Vol. 150, 05.2019, p. 100-111.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    A Comparative Assessment Study of Known Small-Molecule Keap1-Nrf2 Protein-Protein Interaction Inhibitors : Chemical Synthesis, Binding Properties, and Cellular Activity. / Tran, Kim Tai; Pallesen, Jakob S; Solbak, Sara Marie Øie; Narayanan, Dilip; Baig, Amina; Zang, Jie; Aguayo-Orozco, Alejandro; Carmona, Rosa; Garcia, Anthony; Bach, Anders.

    In: Journal of Medicinal Chemistry, Vol. 62, No. 17, 2019, p. 8028-8052.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Molecular architecture of the Jumonji C family histone demethylase KDM5B. / Dorosz, Jerzy; Kristensen, Line Hyltoft; Aduri, Nanda G; Mirza, Osman; Lousen, Rikke; Bucciarelli, Saskia; Mehta, Ved; Sellés-Baiget, Selene; Solbak, Sara Marie Øie; Bach, Anders; Mesa, Pablo; Hernandez, Pablo Alcon; Montoya, Guillermo; Nguyen, Tam T. T. N.; Rand, Kasper D.; Boesen, Thomas; Gajhede, Michael.

    In: Scientific Reports, Vol. 9, 4019, 2019.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. 2018
  6. Published

    Non-covalent Small-Molecule Kelch-like ECH-Associated Protein 1-Nuclear Factor Erythroid 2-Related Factor 2 (Keap1-Nrf2) Inhibitors and Their Potential for Targeting Central Nervous System Diseases. / Pallesen, Jakob S; Tran, Kim T; Bach, Anders.

    In: Journal of Medicinal Chemistry, Vol. 61, No. 18, 11.05.2018, p. 8088-8103.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. 2017
  8. Published

    Effects of the dimeric PSD-95 inhibitor UCCB01-144 on functional recovery after fimbria-fornix transection in rats. / Sommer, Jens Bak; Bach, Anders; Malá, Hana ; Strømgaard, Kristian; Mogensen, Jesper; Pickering, Darryl S.

    In: Pharmacology, Biochemistry and Behavior, Vol. 161, 10.2017, p. 62-67.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    In vitro and in vivo effects of a novel dimeric inhibitor of PSD‐95 on excitotoxicity and functional recovery after experimental traumatic brain injury. / Sommer, Jens Bak; Bach, Anders; Rytter, Hana Malá; Strømgaard, Kristian; Mogensen, Jesper; Pickering, Darryl S.

    In: European Journal of Neuroscience, Vol. 45, No. 2, 20.01.2017, p. 238-248.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Targeting Oxidative Stress in Stroke. / Bach, Anders.

    Neuroprotective Therapy for Stroke and Ischemic Disease. ed. / Paul Lapchak; John H Zhang. Springer, 2017. p. 203-250 (Translational Stroke Research).

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  11. Published

    Effects of dimeric PSD-95 inhibition on excitotoxic cell death and outcome after controlled cortical impact in rats : PSD-95 inhibition in experimental TBI. / Sommer, Jens Bak; Bach, Anders; Rytter, Hana Malá; Gynther, Mikko; Bjerre, Ann-Sofie; Gram, Marie Gajhede; Marschner, Linda; Strømgaard, Kristian; Mogensen, Jesper; Pickering, Darryl S.

    In: Neurochemical Research, Vol. 42, No. 12, 2017, p. 3401-3413.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    PSD-95 uncoupling from NMDA receptors by Tat-N-dimer ameliorates neuronal depolarization in cortical spreading depression. / Kucharz, Krzysztof; Søndergaard Rasmussen, Ida; Bach, Anders; Strømgaard, Kristian; Lauritzen, Martin.

    In: Journal of Cerebral Blood Flow and Metabolism, Vol. 37, No. 5, 2017, p. 1820-1828.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. 2016
  14. Published

    Effects of the dimeric PSD-95 inhibitor UCCB01-144 in mouse models of pain, cognition and motor function. / Andreasen, Jesper T; Nasser, Arafat; Caballero-Puntiverio, Maitane; Sahlholt, Maj; Bach, Anders; Gynther, Mikko; Strømgaard, Kristian; Pickering, Darryl S.

    In: European Journal of Pharmacology, Vol. 780, 05.06.2016, p. 166-73.

    Research output: Contribution to journalJournal articleResearchpeer-review

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