Bente Frølund

Bente Frølund

Professor with special responsibilities


  1. 2019
  2. Published

    Designing Poly-agonists for Treatment of Metabolic Diseases: Challenges and Opportunities. / Petersen, Jonas; Strømgaard, Kristian; Frølund, Bente; Clemmensen, Christoffer.

    In: Drugs, Vol. 79, https://doi.org/10.1007/s40265-019-01153-6, 26.06.2019, p. 1187-1197.

    Research output: Contribution to journalReviewResearchpeer-review

  3. E-pub ahead of print

    Five-membered N-heterocyclic Scaffolds as Novel Amino Bioisosteres at -Aminobutyric Acid (GABA) Type A Receptors and GABA Transporters. / Giraudo, Alessandro; Krall, Jacob; Bavo, Francesco; Nielsen, Birgitte; Kongstad, Kenneth Thermann; Rolando, Barbara; De Blasio, Rosella; Gloriam, David E; Löffler, Rebekka; Thiesen, Louise; Harpsøe, Kasper; Frydenvang, Karla; Boschi, Donatella; Wellendorph, Petrine; Lolli, Marco L; Jensen, Anders A.; Frølund, Bente.

    In: Journal of Medicinal Chemistry, 22.05.2019.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Discovery of 2-(Imidazo[1,2-b]pyridazin-2-yl)acetic Acid as a New Class of Ligands Selective for the γ-Hydroxybutyric Acid (GHB) High-Affinity Binding Sites. / Krall, Jacob; Bavo, Francesco; Falk-Petersen, Christina B; Jensen, Claus Hatt; Nielsen, Julie Olsson; Tian, Yongsong; Anglani, Valeria; Kongstad, Kenneth Thermann; Piilgaard, Louise; Nielsen, Birgitte; Gloriam, David E; Kehler, Jan; Jensen, Anders A.; Harpsøe, Kasper; Wellendorph, Petrine; Frølund, Bente.

    In: Journal of Medicinal Chemistry, Vol. 62, No. 5, 14.03.2019, p. 2798-2813.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. 2018
  6. Published

    4-Hydroxy-1,2,3-triazole moiety as bioisostere of the carboxylic acid function: a novel scaffold to probe the orthosteric gamma-aminobutyric acid receptor binding site. / Alessandro, Giraudo; Krall, Jacob; Nielsen, Birgitte; Sørensen, Troels Ersted; Kongstad, Kenneth Thermann; Barbara, Rolando; Donatella, Boschi; Frølund, Bente; Lolli, Marco L.

    In: European Journal of Medicinal Chemistry, Vol. 158, 05.10.2018, p. 311-321.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Synthesis, pharmacological activity and molecular modeling studies of a series of 2-amino-1,4,5,6-tetrahydropyrimidine-5-carboxylic acid analogues as betaine/GABA transporter 1 (BGT1) substrate-inhibitors. / Kickinger, Stefanie; Al-Khawaja, Anas; Haugaard, Anne Staehr; Loeffler, Rebekka; Damgaard, Maria; Eckert, Gerhard; Frolund, Bente; Wellendorph, Petrine.

    2018. Abstract from 256th National Meeting and Exposition of the American-Chemical-Society (ACS) - Nanoscience, Nanotechnology and Beyond, United States.

    Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

  8. Published

    Structure–Function Evaluation of Imidazopyridine Derivatives Selective for δ-Subunit-Containing γ-Aminobutyric Acid Type A (GABAA) Receptors. / Yakoub, Kirsten; Jung, Sascha; Sattler, Christian; Damerow, Helen; Weber, Judith; Kretzschmann, Annika; Cankaya, Aylin S.; Piel, Markus; Rösch, Frank; Haugaard, Anne S.; Frølund, Bente; Schirmeister, Tanja; Lüddens, Hartmut.

    In: Journal of Medicinal Chemistry, Vol. 61, No. 5, 08.03.2018, p. 1951-1968.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Pharmacological Characterization of [3H]ATPCA as a Substrate for Studying the Functional Role of the Betaine/GABA Transporter 1 and the Creatine Transporter. / Al-Khawaja, Anas; Haugaard, Anne S; Marek, Ales; Löffler, Rebekka; Thiesen, Louise; Santiveri, Monica; Damgaard, Maria; Bundgaard, Christoffer; Frølund, Bente; Wellendorph, Petrine.

    In: A C S Chemical Neuroscience, Vol. 9, No. 3, 2018, p. 545–554.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. 2017
  11. Published

    Development of a Robust Mammalian Cell-based Assay for Studying Recombinant α4 β1/3 δ GABAA Receptor Subtypes. / Falk-Petersen, Christina B; Søgaard, Rikke; Madsen, Kenneth L; Klein, Anders B; Frølund, Bente; Wellendorph, Petrine.

    In: Basic & Clinical Pharmacology & Toxicology, Vol. 121, No. 2, 08.2017, p. 119-129.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Discovery and Evaluation of Anti-Fibrinolytic Plasmin Inhibitors Derived from 5-(4-Piperidyl)isoxazol-3-ol (4-PIOL). / Schmidt, Thomas C.; Eriksson, Per-Olof; Gustafsson, David; Cosgrove, David; Frølund, Bente; Boström, Jonas.

    In: Journal of Chemical Information and Modeling, Vol. 57, No. 7, 24.07.2017, p. 1703-1714.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Monastrol, a 3,4-dihydropyrimidin-2(1H)-thione, as structural scaffold for the development of modulators for GHB high-affinity binding sites and α1β2δ GABAA receptors. / Damgaard, Maria; Al-Khawaja, Anas; Nittegaard-Nielsen, Mia; Petersen, Rebekka F; Wellendorph, Petrine; Frølund, Bente.

    In: European Journal of Medicinal Chemistry, Vol. 138, 15.06.2017, p. 300-312.

    Research output: Contribution to journalJournal articleResearchpeer-review

Previous 1 2 3 4 5 6 7 8 ...13 Next

ID: 1302625