Employees – University of Copenhagen

Bente Frølund

Bente Frølund

Professor with special responsibilities


  1. 2015
  2. Published

    Conformationally restrained carbamoylcholine homologues. Synthesis, pharmacology at neuronal nicotinic acetylcholine receptors and biostructural considerations. / de la Fuente Revenga, M; Balle, Thomas; Jensen, Anders A.; Frølund, Bente.

    In: European Journal of Medicinal Chemistry, Vol. 102, 2015, p. 352-362 .

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Differential interactions of 5-(4-piperidyl)-3-isoxazolol analogues with insect γ-aminobutyric acid receptors leading to functional selectivity. / Liu, Genyan; Frølund, Bente; Ozoe, Fumiyo; Ozoe, Yoshihisa.

    In: Insect Biochemistry and Molecular Biology, Vol. 66, 2015, p. 64-71.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Exploration of the molecular architecture of the orthosteric binding site in the α4β2 nicotinic acetylcholine receptor with analogs of 3-(dimethylamino)butyl dimethylcarbamate (DMABC) and 1-(pyridin-3-yl)-1,4-diazepane. / Bach, Tinna Brøbech; Jensen, Anders A.; Petersen, Jette G.; Sørensen, Troels E.; Volpe, S.D.; Liu, J.; Blaazer, A.R.; van Muijlwijk-Koezen, J.E.; Balle, Thomas; Frølund, Bente.

    In: European Journal of Medicinal Chemistry, Vol. 102, 2015, p. 425-444 .

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    GABAA receptor partial agonists and antagonists : structure, binding mode, and pharmacology. / Krall, Jacob; Balle, Thomas; Krogsgaard-Larsen, Niels; Sørensen, Troels E; Krogsgaard-Larsen, Povl; Kristiansen, Uffe; Frølund, Bente.

    Diversity and functions of GABA receptors: A tribute to Hanns Möhler, Part A. Vol. 72 2015. p. 201-27.

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  6. Published

    Identification of the first highly selective inhibitor of human GABA transporter GAT3. / Damgaard, Maria; Al-Khawaja, Anas; Vogensen, Stine B.; Jurik, A; Sijm, M; Lie, M; Bæk, M.I.; Rosenthal, Emil; Jensen, Anders A.; Ecker, G.F.; Frølund, Bente; Wellendorph, Petrine; Clausen, Rasmus P.

    In: A C S Chemical Neuroscience, Vol. 6, 2015, p. 1591-1599.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    In vitro and in vivo evidence for active brain uptake of the GHB analogue HOCPCA by the monocarboxylate transporter subtype 1. / Thiesen, Louise; Kehler, Jan; Clausen, Rasmus P; Frølund, Bente; Bundgaard, Christoffer; Wellendorph, Petrine.

    In: Journal of Pharmacology and Experimental Therapeutics, Vol. 354, No. 2, 2015, p. 166-174 .

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. 2014
  9. Published

    Positive allosteric modulation of the GHB high-affinity binding site by the GABAA receptor modulator monastrol and the flavonoid catechin. / Eghorn, Laura Friis; Høstgaard-Jensen, Kirsten; Kongstad, Kenneth Thermann; Bay, Tina; Higgins, David; Frølund, Bente; Wellendorph, Petrine.

    In: European Journal of Pharmacology, Vol. 740, 05.10.2014, p. 570-577.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    The GABAA Antagonist DPP-4-PIOL Selectively Antagonises Tonic over Phasic GABAergic Currents in Dentate Gyrus Granule Cells. / Boddum, Kim; Frølund, Bente; Kristiansen, Uffe.

    In: Neurochemical Research, Vol. 39, No. 11, 08.08.2014, p. 2078–2084.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Pharmacological Identification of a Guanidine-Containing β-Alanine Analogue with Low Micromolar Potency and Selectivity for the Betaine/GABA Transporter 1 (BGT1). / Al-Khawaja, Anas Mohammad Ali; Petersen, Jette Gellert; Damgaard, Maria; Jensen, Mette Høgh; Vogensen, Stine Byskov; Lie, Maria Elena Klibo; Kragholm, Bolette; Bräuner-Osborne, Hans; Clausen, Rasmus Prætorius; Frølund, Bente; Wellendorph, Petrine.

    In: Neurochemical Research, Vol. 39, No. 10, 23.05.2014, p. 1988-1996.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    5-(Piperidin-4-yl)-3-Hydroxypyrazole: A Novel Scaffold for Probing the Orthosteric γ-Aminobutyric Acid Type A Receptor Binding Site. / Krall, Jacob; Kongstad, Kenneth Thermann; Nielsen, Birgitte; Sørensen, Troels Ersted; Balle, Thomas; Jensen, Anders A.; Frølund, Bente.

    In: ChemMedChem, Vol. 9, No. 11, 2014, p. 2475-2485.

    Research output: Contribution to journalJournal articleResearchpeer-review

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