Employees – University of Copenhagen

Bente Frølund

Bente Frølund

Associate Professor


  1. 2009
  2. Published

    Carbamoylcholine analogs as nicotinic acetylcholine receptor agonists--structural modifications of 3-(dimethylamino)butyl dimethylcarbamate (DMABC). / Hansen, Camilla Petrycer; Jensen, Anders Asbjørn; Balle, Thomas; Bitsch-Jensen, Klaus; Hassan, Mohamud M; Liljefors, Tommy; Frølund, Bente.

    In: Bioorganic & Medicinal Chemistry Letters, Vol. 19, No. 1, 2009, p. 87-91.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. 2008
  4. Published

    Ligands for the GABA recognition site at the GABAA receptor: Structure-activity studies. / Frølund, Bente Flensborg; Kristiansen, Uffe; Krogsgaard-Larsen, Povl; Liljefors, Tommy.

    Chemistry and molecular aspects of drug design and action. ed. / E.A. Rekka; P.N. Kourounakis. Boca Raton, Fl : CRC Press, 2008. p. 139-147.

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearch

  5. Published

    Novel acetylcholine and carbamoylcholine analogues : Development of a functionally selective a4ß2 nicotinic acetylcholine receptor agonist. / Hansen, Camilla Petrycer; Jensen, Anders Asbjørn; Christensen, Jeppe K.; Balle, Thomas; Liljefors, Tommy; Frølund, Bente Flensborg.

    In: Journal of Medicinal Chemistry, Vol. 51, No. 23, 2008, p. 7380-7395.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Novel high-affinity and selective biaromatic 4-substituted ¿-hydroxybutyric acid (GHB) analogues as GHB ligands : design, synthesis, and binding studies. / Høg, Signe; Wellendorph, Petrine; Nielsen, Birgitte; Frydenvang, Karla; Dahl, Ivar F; Bräuner-Osborne, Hans; Brehm, Lotte; Frølund, Bente; Clausen, Rasmus P.

    In: Journal of Medicinal Chemistry, Vol. 51, No. 24, 2008, p. 8088-8095.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Transport of amino acids and GABA analogues via the human proton-coupled amino acid transporter, hPAT1 : Characterization of conditions for affinity and transport experiments in Caco-2 cells. / Larsen, Mie; Larsen, Birger Brodin; Frølund, Bente; Nielsen, Carsten Uhd.

    In: European Journal of Pharmaceutical Sciences, Vol. 35, No. 1-2, 2008, p. 86-95.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Inhibition of the betaine-GABA transporter (mGAT2/BGT-1) modulates spontaneous electrographic bursting in the medial entorhinal cortex (mEC). / Smith, Misty D.; Saunders, Gerald W.; Clausen, Rasmus Prætorius; Frølund, Bente Flensborg; Krogsgaard-Larsen, Povl; Larsson, Orla Miller; Schousboe, Arne; Wilcox, Karen S.; White, H. Steve.

    In: Epilepsy Research, Vol. 79, No. 1, 2008, p. 6-13.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. 2007
  10. Published

    The human proton-coupled amino acid transporter (hPAT1) is a transport system for GABA-like drugs. / Broberg, Mie Larsen; Frølund, Bente; Brodin, Birger; Nielsen, Carsten Uhd.

    2007. Abstract from 22007 Annual AAPS Meeting, San Diego, United States.

    Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

  11. Published

    7-substituted-melatonin and 7-substituted-1-methylmelatonin analogues: Effect of substituents on potency and binding affinity. / Faust, Rüdiger; Garratt, Peter J.; Pérez, Maria Angeles Trujillo; Piccio, Vincent J.-D.; Madsen, Christian; Stenstrøm, Ane; Frølund, Bente Flensborg; Davidson, Kathryn; Teh, Muy-Teck; Sugden, David.

    In: Bioorganic & Medicinal Chemistry, Vol. 15, No. 13, 2007, p. 4543-4551.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    4-aryl-5-(4-piperidyl)-3-isoxazolol GABAA antagonists: synthesis, pharmacology, and structure-activity relationships. / Frølund, Bente Flensborg; Jensen, Lars S.; Storustovu, Signe I.; Stensbøl, Tine Bryan; Ebert, Bjarke; Kehler, Jan; Krogsgaard-Larsen, Povl; Liljefors, Tommy.

    In: Journal of Medicinal Chemistry, Vol. 50, No. 8, 2007, p. 1988-1992.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    5-substituted imidazole-4-acetic acid analogues: synthesis, modeling, and pharmacological characterization of a series of novel ¿-aminobutyric acidC receptor agonists. / Madsen, Christian; Jensen, Anders Asbjørn; Liljefors, Tommy; Kristiansen, Uffe; Nielsen, Birgitte; Hansen, Camilla Petrycer; Larsen, Mogens; Ebert, Bjarke; Bang-Andersen, Benny; Krogsgaard-Larsen, Povl; Frølund, Bente Flensborg.

    In: Journal of Medicinal Chemistry, Vol. 50, No. 17, 2007, p. 4147-4161.

    Research output: Contribution to journalJournal articleResearchpeer-review

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