Employees – University of Copenhagen

Bente Frølund

Bente Frølund

Associate Professor


  1. 2015
  2. Published

    Exploration of the molecular architecture of the orthosteric binding site in the α4β2 nicotinic acetylcholine receptor with analogs of 3-(dimethylamino)butyl dimethylcarbamate (DMABC) and 1-(pyridin-3-yl)-1,4-diazepane. / Bach, Tinna Brøbech; Jensen, Anders A.; Petersen, Jette G.; Sørensen, Troels E.; Volpe, S.D.; Liu, J.; Blaazer, A.R.; van Muijlwijk-Koezen, J.E.; Balle, Thomas; Frølund, Bente.

    In: European Journal of Medicinal Chemistry, Vol. 102, 2015, p. 425-444 .

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Identification of the first highly selective inhibitor of human GABA transporter GAT3. / Damgaard, Maria; Al-Khawaja, Anas; Vogensen, Stine B.; Jurik, A; Sijm, M; Lie, M; Bæk, M.I.; Rosenthal, Emil; Jensen, Anders A.; Ecker, G.F.; Frølund, Bente; Wellendorph, Petrine; Clausen, Rasmus P.

    In: A C S Chemical Neuroscience, Vol. 6, 2015, p. 1591-1599.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    GABAA receptor partial agonists and antagonists : structure, binding mode, and pharmacology. / Krall, Jacob; Balle, Thomas; Krogsgaard-Larsen, Niels; Sørensen, Troels E; Krogsgaard-Larsen, Povl; Kristiansen, Uffe; Frølund, Bente.

    Diversity and functions of GABA receptors: A tribute to Hanns Möhler, Part A. Vol. 72 2015. p. 201-27.

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  5. Published

    Differential interactions of 5-(4-piperidyl)-3-isoxazolol analogues with insect γ-aminobutyric acid receptors leading to functional selectivity. / Liu, Genyan; Frølund, Bente; Ozoe, Fumiyo; Ozoe, Yoshihisa.

    In: Insect Biochemistry and Molecular Biology, Vol. 66, 2015, p. 64-71.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Substituted 4-hydroxy-1,2,3-triazoles : synthesis, characterization and first drug design applications through bioisosteric modulation and scaffold hopping approaches. / Pippione, Agnese C.; Dosio, Franco; Ducime, Alex; Federico, Antonella; Martina, Katia; Sainas, Stefano; Frølund, Bente; Gooyit, Major; Janda, Kim D.; Boschi, Donatella; Lolli, Marco L.

    In: MedChemComm, Vol. 6, No. 7, 01.07.2015, p. 1285-1292.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    In vitro and in vivo evidence for active brain uptake of the GHB analogue HOCPCA by the monocarboxylate transporter subtype 1. / Thiesen, Louise; Kehler, Jan; Clausen, Rasmus P; Frølund, Bente; Bundgaard, Christoffer; Wellendorph, Petrine.

    In: Journal of Pharmacology and Experimental Therapeutics, Vol. 354, No. 2, 2015, p. 166-174 .

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Conformationally restrained carbamoylcholine homologues. Synthesis, pharmacology at neuronal nicotinic acetylcholine receptors and biostructural considerations. / de la Fuente Revenga, M; Balle, Thomas; Jensen, Anders A.; Frølund, Bente.

    In: European Journal of Medicinal Chemistry, Vol. 102, 2015, p. 352-362 .

    Research output: Contribution to journalJournal articleResearchpeer-review

ID: 1302625