Brian Lohse

Brian Lohse

Associate Professor


  1. 2014
  2. Published

    Analogues of the natural product Sinefungin as inhibitors of EHMT1 and EHMT2

    Devkota, K., Lohse, Brian, Liu, Q., Wang, M., Stærk, Dan, Berthelsen, J. & Clausen, Rasmus Prætorius, 2014, In : A C S Medicinal Chemistry Letters. 5, 4, p. 293-297

    Research output: Contribution to journalLetterResearchpeer-review

  3. Published

    Dissecting the Binding Mode of Low Affinity Phage Display Peptide Ligands to Protein Targets by Hydrogen/Deuterium Exchange Coupled to Mass Spectrometry

    Leurs, U., Lohse, Brian, Ming, S. A., Cole, P. A., Clausen, Rasmus Prætorius, Kristensen, Jesper Langgaard & Rand, Kasper Dyrberg, 17 Oct 2014, In : Analytical Chemistry. 86, 23, p. 11734-11741 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Substrate- and Cofactor-independent Inhibition of Histone Demethylase KDM4C

    Leurs, U., Lohse, Brian, Rand, Kasper Dyrberg, Ming, S., Riise, E. S., Cole, P. A., Kristensen, Jesper Langgaard & Clausen, Rasmus Prætorius, 11 Jul 2014, In : A C S Chemical Biology. 9, 9, p. 2131-2138 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. 2013
  6. Published

    Posttranslational Modifications of the Histone 3 Tail and Their Impact on the Activity of Histone Lysine Demethylases In Vitro

    Lohse, Brian, Helgstrand, C., Andersson, J. L., Leurs, U., Cloos, Paul, Kristensen, Jesper Langgaard & Clausen, Rasmus Prætorius, 2 Jul 2013, In : P L o S One. 8, 7, p. e67653

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. 2012
  8. Published

    Inhibitor scaffold for the histone lysine demethylase KDM4C (JMJD2C)

    Leurs, U., Clausen, Rasmus Prætorius, Kristensen, Jesper Langgaard & Lohse, Brian, 15 Sep 2012, In : Bioorganic & Medicinal Chemistry Letters. 22, 18, p. 5811-3 3 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. 2011
  10. Published

    Inhibitors of histone demethylases

    Lohse, Brian, Kristensen, Jesper Langgaard, Kristensen, L. H., Agger, Karl, Helin, Kristian, Gajhede, Michael & Clausen, Rasmus Prætorius, 1 Feb 2011, In : Bioorganic & Medicinal Chemistry. 19, 12, p. 3625-3636 11 p.

    Research output: Contribution to journalReviewResearchpeer-review

  11. Published

    Targeting histone lysine demethylases by truncating the histone 3 tail to obtain selective substrate-based inhibitors

    Lohse, Brian, Nielsen, A. L., Kristensen, J. B. L., Helgstrand, C., Cloos, Paul, Olsen, L., Gajhede, Michael, Clausen, Rasmus Prætorius & Kristensen, Jesper Langgaard, 19 Sep 2011, In : Angewandte Chemie International Edition. 50, 39, p. 9100-9103

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. 2010
  13. Published

    Histonhaler: et nyt mål inden for kræftbehandling

    Kristensen, Jesper Langgaard, Lohse, Brian & Clausen, Rasmus Prætorius, Dec 2010, In : Lægemiddelforskning. 2010, p. 7-9

    Research output: Contribution to journalJournal articleCommunication

  14. 2008
  15. Published

    Encapsulation efficiency measured on single small unilamellar vesicles

    Lohse, Brian, Bolinger, P. Y. & Stamou, Dimitrios, 2008, In : Journal of the American Chemical Society. 130, 44, p. 14372-14373 1 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16.  Acridizinium-Substituted Dendrimers As a New Potential Rewritable Optical Data Storage Material for Blu-ray

    Lohse, Brian, 2008, In : Chemistry of Materials. 20, 21, p. 6715-6720 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

ID: 544666