Brian Lohse
Brian Lohse

Associate Professor


  1. Published

    Analogues of the natural product Sinefungin as inhibitors of EHMT1 and EHMT2

    Devkota, K., Lohse, Brian, Liu, Q., Wang, M., Stærk, Dan, Berthelsen, J. & Clausen, Rasmus Prætorius, 2014, In : A C S Medicinal Chemistry Letters. 5, 4, p. 293-297

    Research output: Contribution to journalLetterResearchpeer-review

  2. Published

    A fluorescence resonance energy transfer-based method for histone methyltransferases

    Devkota, K., Lohse, Brian, Nyby Jakobsen, C., Berthelsen, J. & Clausen, Rasmus Prætorius, 19 Feb 2015, In : Analytical Biochemistry. 476, p. 78-80 3 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Histonhaler: et nyt mål inden for kræftbehandling

    Kristensen, Jesper Langgaard, Lohse, Brian & Clausen, Rasmus Prætorius, Dec 2010, In : Lægemiddelforskning. 2010, p. 7-9

    Research output: Contribution to journalJournal articleCommunication

  4. Published

    Danger in the reef: Proteome, toxicity, and neutralization of the venom of the olive sea snake, Aipysurus laevis

    Laustsen, A. H., Gutiérrez, J. M., Rasmussen, A. R., Engmark, M., Gravlund, P., Sanders, K. L., Lohse, Brian & Lomonte, B., 1 Dec 2015, In : Toxicon. 107, p. 187-96 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Selecting key toxins for focused development of elapid snake antivenoms and inhibitors guided by a Toxicity Score

    Laustsen, A. H. & Lohse, Brian, 15 Sep 2015, In : Toxicon. 104, p. 43-45 3 p.

    Research output: Contribution to journalLetterResearchpeer-review

  6. Published

    Pitfalls to avoid when using phage display for snake toxins

    Laustsen, A. H., Lauridsen, L. P., Lomonte, B., Andersen, M. R. & Lohse, Brian, Feb 2017, In : Toxicon. 126, p. 79-89 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Snake venomics of monocled cobra (Naja kaouthia) and investigation of human IgG response against venom toxins

    Laustsen, A. H., Lohse, Brian & Rasmussen, A. R., 2015, In : Toxicon. 99, p. 23-35 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    From Fangs to Pharmacology: The Future of Snakebite Envenoming Therapy

    Laustsen, A. H., Engmark, M., Milbo, C., Johannesen, J., Lomonte, B., Gutiérrez, J. M. & Lohse, Brian, 2016, In : Current Pharmaceutical Design. 22, 34, p. 5270-5293 24 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Unveiling the nature of black mamba (Dendroaspis polylepis) venom through venomics and antivenom immunoprofiling: Identification of key toxin targets for antivenom development

    Laustsen, A. H., Lomonte, B., Lohse, Brian, Fernandez, J. & Gutiérrez, J. M., 2015, In : Journal of Proteomics. 119, p. 126–142 17 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Inhibitor scaffold for the histone lysine demethylase KDM4C (JMJD2C)

    Leurs, Ulrike, Clausen, Rasmus Prætorius, Kristensen, Jesper Langgaard & Lohse, Brian, 15 Sep 2012, In : Bioorganic & Medicinal Chemistry Letters. 22, 18, p. 5811-3 3 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Dissecting the Binding Mode of Low Affinity Phage Display Peptide Ligands to Protein Targets by Hydrogen/Deuterium Exchange Coupled to Mass Spectrometry

    Leurs, Ulrike, Lohse, Brian, Ming, S. A., Cole, P. A., Clausen, Rasmus Prætorius, Kristensen, Jesper Langgaard & Rand, Kasper Dyrberg, 17 Oct 2014, In : Analytical Chemistry. 86, 23, p. 11734-11741 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Substrate- and Cofactor-independent Inhibition of Histone Demethylase KDM4C

    Leurs, Ulrike, Lohse, Brian, Rand, Kasper Dyrberg, Ming, S., Riise, E. S., Cole, P. A., Kristensen, Jesper Langgaard & Clausen, Rasmus Prætorius, 11 Jul 2014, In : A C S Chemical Biology. 9, 9, p. 2131-2138 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Encapsulation efficiency measured on single small unilamellar vesicles

    Lohse, Brian, Bolinger, P. Y. & Stamou, Dimitrios, 2008, In : Journal of the American Chemical Society. 130, 44, p. 14372-14373 1 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Self-assembly of uracil-PAMAM dendrimer systems into domains of micrometer length scale

    Lohse, Brian, 2007, In : Macromolecules. 40, 6, p. 1779-1781 3 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. UV-Photodimerization in Uracil-substituted dendrimers for high density data storage

    Lohse, Brian, 2007, In : Journal of Polymer Science. Part A, Polymer Chemistry. 45, 19, p. 4401-4412 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Photodimerization in substituted di- and oligopeptides by UV-light for optical data storage: Part 2

    Lohse, Brian, 2005, In : Biopolymers. 80, 4, p. 576

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Posttranslational Modifications of the Histone 3 Tail and Their Impact on the Activity of Histone Lysine Demethylases In Vitro

    Lohse, Brian, Helgstrand, C., Andersson, J. L., Leurs, Ulrike, Cloos, Paul, Kristensen, Jesper Langgaard & Clausen, Rasmus Prætorius, 2 Jul 2013, In : P L o S One. 8, 7, p. e67653

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Photodimerization in pyrimidine-substituted dipeptides

    Lohse, Brian, 2005, In : Journal of Peptide Science. 11, 8, p. 499-505 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19.  Acridizinium-Substituted Dendrimers As a New Potential Rewritable Optical Data Storage Material for Blu-ray

    Lohse, Brian, 2008, In : Chemistry of Materials. 20, 21, p. 6715-6720 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Photodimerization in substituted di- and oligopeptides by UV-light for optical data storage: Part 1

    Lohse, Brian, 2005, In : Biopolymers. 80, 4, p. 504

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Cycloaddition in peptides for high-capacity optical storage

    Lohse, Brian, 2006, In : Japanese Journal of Applied Physics. 45, 1B, p. 488-492 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Targeting histone lysine demethylases by truncating the histone 3 tail to obtain selective substrate-based inhibitors

    Lohse, Brian, Nielsen, A. L., Kristensen, J. B. L., Helgstrand, C., Cloos, Paul, Olsen, L., Gajhede, Michael, Clausen, Rasmus Prætorius & Kristensen, Jesper Langgaard, 19 Sep 2011, In : Angewandte Chemie International Edition. 50, 39, p. 9100-9103

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Inhibitors of histone demethylases

    Lohse, Brian, Kristensen, Jesper Langgaard, Kristensen, L. H., Agger, Karl, Helin, Kristian, Gajhede, Michael & Clausen, Rasmus Prætorius, 1 Feb 2011, In : Bioorganic & Medicinal Chemistry. 19, 12, p. 3625-3636 11 p.

    Research output: Contribution to journalReviewResearchpeer-review

  24. Organic materials for UV holographic and digital storage

    Lohse, Brian, 2006, Proceedings of SPIE. SPIE - International Society for Optical Engineering, p. 6252 7 p.

    Research output: Chapter in Book/Report/Conference proceedingArticle in proceedingsResearchpeer-review

  25. Published

    Self-assembly of uracil-PAMAM dendrimer systems into domains of micrometer length scale

    Lohse, Brian, Ivanov, M. T., Andreasen, J. W., Vestberg, R., Hvilsted, S., Berg, R. H., Ramanujam, P. S., Hawker, C. J. & Mortensen, Kell, 20 Mar 2007, In : Macromolecules. 40, 6, p. 1779-1781

    Research output: Contribution to journalJournal articleResearchpeer-review

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