Brian Lohse
Brian Lohse

Associate Professor


  1. 2014
  2. Published

    Substrate- and Cofactor-independent Inhibition of Histone Demethylase KDM4C

    Leurs, Ulrike, Lohse, Brian, Rand, Kasper Dyrberg, Ming, S., Riise, E. S., Cole, P. A., Kristensen, Jesper Langgaard & Clausen, Rasmus Prætorius, 11 Jul 2014, In : A C S Chemical Biology. 9, 9, p. 2131-2138 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. 2013
  4. Published

    Posttranslational Modifications of the Histone 3 Tail and Their Impact on the Activity of Histone Lysine Demethylases In Vitro

    Lohse, Brian, Helgstrand, C., Andersson, J. L., Leurs, Ulrike, Cloos, Paul, Kristensen, Jesper Langgaard & Clausen, Rasmus Prætorius, 2 Jul 2013, In : P L o S One. 8, 7, p. e67653

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. 2012
  6. Published

    Inhibitor scaffold for the histone lysine demethylase KDM4C (JMJD2C)

    Leurs, Ulrike, Clausen, Rasmus Prætorius, Kristensen, Jesper Langgaard & Lohse, Brian, 15 Sep 2012, In : Bioorganic & Medicinal Chemistry Letters. 22, 18, p. 5811-3 3 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. 2011
  8. Published

    Inhibitors of histone demethylases

    Lohse, Brian, Kristensen, Jesper Langgaard, Kristensen, L. H., Agger, Karl, Helin, Kristian, Gajhede, Michael & Clausen, Rasmus Prætorius, 1 Feb 2011, In : Bioorganic & Medicinal Chemistry. 19, 12, p. 3625-3636 11 p.

    Research output: Contribution to journalReviewResearchpeer-review

  9. Published

    Targeting histone lysine demethylases by truncating the histone 3 tail to obtain selective substrate-based inhibitors

    Lohse, Brian, Nielsen, A. L., Kristensen, J. B. L., Helgstrand, C., Cloos, Paul, Olsen, L., Gajhede, Michael, Clausen, Rasmus Prætorius & Kristensen, Jesper Langgaard, 19 Sep 2011, In : Angewandte Chemie International Edition. 50, 39, p. 9100-9103

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. 2010
  11. Published

    Histonhaler: et nyt mål inden for kræftbehandling

    Kristensen, Jesper Langgaard, Lohse, Brian & Clausen, Rasmus Prætorius, Dec 2010, In : Lægemiddelforskning. 2010, p. 7-9

    Research output: Contribution to journalJournal articleCommunication

  12. 2008
  13. Published

    Encapsulation efficiency measured on single small unilamellar vesicles

    Lohse, Brian, Bolinger, P. Y. & Stamou, Dimitrios, 2008, In : Journal of the American Chemical Society. 130, 44, p. 14372-14373 1 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14.  Acridizinium-Substituted Dendrimers As a New Potential Rewritable Optical Data Storage Material for Blu-ray

    Lohse, Brian, 2008, In : Chemistry of Materials. 20, 21, p. 6715-6720 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. 2007
  16. Published

    Self-assembly of uracil-PAMAM dendrimer systems into domains of micrometer length scale

    Lohse, Brian, Ivanov, M. T., Andreasen, J. W., Vestberg, R., Hvilsted, S., Berg, R. H., Ramanujam, P. S., Hawker, C. J. & Mortensen, Kell, 20 Mar 2007, In : Macromolecules. 40, 6, p. 1779-1781

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Self-assembly of uracil-PAMAM dendrimer systems into domains of micrometer length scale

    Lohse, Brian, 2007, In : Macromolecules. 40, 6, p. 1779-1781 3 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

ID: 544666