Darryl S Pickering

Darryl S Pickering

Associate Professor


  1. 2016
  2. Published

    Studies on Aryl-Substituted Phenylalanines: Synthesis, Activity, and Different Binding Modes at AMPA Receptors. / Szymanska, Ewa; Frydenvang, Karla Andrea; Pickering, Darryl S; Krintel, Christian; Nielsen, Birgitte; Kooshki, Ayesheh; Zachariassen, Linda Grønborg; Olsen, Lars; Kastrup, Jette Sandholm Jensen; Johansen, Tommy Nørskov.

    In: Journal of Medicinal Chemistry, Vol. 59, No. 1, 2016, p. 448-461.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Design, synthesis and structure-activity relationships of novel phenylalanine-based amino acids as kainate receptors ligands. / Szymańska, Ewa; Chałupnik, Paulina; Szczepańska, Katarzyna; Moral, Ana Maria Cuñado; Pickering, Darryl S; Nielsen, Birgitte; Johansen, Tommy Nørskov; Kieć-Kononowicz, Kieć-Kononowicz.

    In: Bioorganic & Medicinal Chemistry Letters, Vol. 26, No. 22, 2016, p. 5568-5572.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    γ-Glutamyl-dipeptides: Easy tools to rapidly probe the stereoelectronic properties of ionotropic glutamate receptor binding pocket. / Tamborini, Lucia; Nicosia, Veronica; Conti, Paola; Dall'Oglio, Federica; De Micheli, Carlo; Nielsen, Birgitte; Jensen, Anders A.; Pickering, Darryl S; Pinto, Andrea.

    In: Tetrahedron, Vol. 72, No. 51, 01.12.2016, p. 8586-8492.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Tweaking subtype-selectivity and agonist efficacy at (S)-2-amino-3-(3-hydroxy-5-methyl-isoxazol-4-yl)propionic acid (AMPA) receptors in a small series of BnTetAMPA analogues. / Wang, Shuang-Yan; Larsen, Younes; Navarrete, Cristina V.; Jensen, Anders A.; Nielsen, Birgitte; Al-Musaed, Ali; Frydenvang, Karla; Kastrup, Jette Sandholm; Pickering, Darryl S; Clausen, Rasmus Prætorius.

    In: Journal of Medicinal Chemistry, Vol. 59, No. 5, 2016, p. 2244-2254.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Structural rearrangement of the intracellular domains during AMPA receptor activation. / Zachariassen, Linda Grønborg; Katchan, Ljudmila; Jensen, Anna Guldvang; Pickering, Darryl S; Plested, Andrew; Kristensen, Anders Skov.

    In: Proceedings of the National Academy of Sciences USA (PNAS), Vol. 113, No. 27, 2016, p. E3950-E3959.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. 2017
  8. Published

    Revisiting the Quinoxalinedione scaffold in the Construction of New Ligands for the Ionotropic Glutamate Receptors. / Demmer, Charles Sylvain; Rombach, David; Liu, Na; Nielsen, Birgitte; Pickering, Darryl S; Bunch, Lennart.

    In: A C S Chemical Neuroscience, Vol. 8, No. 11, 01.12.2017, p. 2477-2495.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Augmentation of Anticancer Drug Efficacy in Murine Hepatocellular Carcinoma Cells by a Peripherally Acting Competitive N-Methyl-d-aspartate (NMDA) Receptor Antagonist. / Gynther, Mikko; Proietti Silvestri, Ilaria; Hansen, Jacob C; Hansen, Kasper B; Malm, Tarja; Ishchenko, Yevheniia; Larsen, Younes; Han, Liwei; Kayser, Silke; Auriola, Seppo; Petsalo, Aleksanteri; Nielsen, Birgitte; Pickering, Darryl S; Bunch, Lennart.

    In: Journal of Medicinal Chemistry, Vol. 60, No. 23, 14.12.2017, p. 9885-9904.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Design and Synthesis of a Series of L-trans-4-Substituted Prolines as Selective Antagonists for the Ionotropic Glutamate Receptors Including Functional and X-ray Crystallographic Studies of New Subtype Selective Kainic Acid Receptor Subtype 1 (GluK1) Antagonist (2S,4R)-4-(2-Carboxyphenoxy)pyrrolidine-2-carboxylic Acid. / Krogsgaard-Larsen, Niels; Delgar, Claudia; Koch, Karina; Brown, Patricia M G E; Møller, Charlotte; Han, Liwei; Huynh, Tri Hien Viet; Hansen, Stinne Wessel; Nielsen, Birgitte; Bowie, Derek; Pickering, Darryl S; Kastrup, Jette Sandholm Jensen; Frydenvang, Karla Andrea; Bunch, Lennart.

    In: Journal of Medicinal Chemistry, Vol. 60, No. 1, 2017, p. 441-457.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Lessons from crystal structures of kainate receptors. / Møllerud, Stine; Frydenvang, Karla Andrea; Pickering, Darryl S; Kastrup, Jette Sandholm Jensen.

    In: Neuropharmacology, Vol. 112, No. Part A, 01.01.2017, p. 16-28.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Pharmacology and crystal structure of novel 2,3-quinoxalinediones at kainate receptors. / Møllerud, Stine; Pallesen, Jakob Staun; Pasini, Diletta; Marconi, Laura; Han, Liwei; Bornholt, Jan; Johansen, Tommy Nørskov; Kastrup, Jette Sandholm ; Pickering, Darryl S; Frydenvang, Karla Andrea.

    In: Journal of Neurochemistry, Vol. 142, No. S1, MTU07-13, 08.2017, p. 124.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

ID: 1299533