Darryl S Pickering
Darryl S Pickering

Associate Professor


  1. Published

    Partial agonism and antagonism of the ionotropic glutamate receptor iGLuR5: Structures of the ligand-bining core in complex with domoic acid and 2-amino-3-[5-tert-butyl-3-(phosphonomethoxy)-4-isoxazolyl]propionic acid

    Hald, H., Naur, P., Pickering, Darryl S, Sprogøe, D., Madsen, Ulf, Timmermann, D. B., Ahring, P. K., Liljefors, T., Schousboe, Arne, Egebjerg, J., Gajhede, Michael & Kastrup, Jette Sandholm Jensen, 2007, In : Journal of Biological Chemistry. 282, 35, p. 25726-25736

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Published

    Pharmacological and structural characterization of conformationally restricted (S)-glutamate analogues at ionotropic glutamate receptors

    Juknaite, L., Venskutonyte, R., Assaf, Z., Faure, S., Gefflaut, T., Aitken, D. J., Nielsen, Birgitte, Gajhede, Michael, Kastrup, Jette Sandholm Jensen, Bunch, Lennart, Frydenvang, Karla Andrea & Pickering, Darryl S, 2012, In : Journal of Structural Biology. 180, 1, p. 39-46

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Pharmacological characterisation of biarylisopropylalsulphonamide AMPA-R potentiators

    Pickering, Darryl S, Sanz, C., Harpsøe, Kasper, Clausen, Rasmus Prætorius, Sauerberg, P., Liljefors, T., Madsen, Ulf & Kaae, B. H., 2007, In : Journal of Neurochemistry. 102 (suppl. 1), 41

    Research output: Contribution to journalConference abstract in journalResearch

  4. Published

    Pharmacological characterization of (4R)-alkyl glutamate analogues at the ionotropic glutamate receptors: focus on subtypes iGlu5-7

    Bunch, Lennart, Gefflaut, T., Alaux, S., Sagot, E., Nielsen, Birgitte & Pickering, Darryl S, 2009, In : European Journal of Pharmacology. 609, p. 1-4

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Rational Design, Synthesis and Pharmacological Evaluation of the (2R)- and (2S)-Stereoisomers of 3-(2-Carboxypyrrolidinyl)-2-methyl Acetic Acid as Ligands for the Ionotropic Glutamate Receptors.

    Rasmussen, J., Storgaard, M., Pickering, Darryl S & Bunch, Lennart, 7 Mar 2011, In : ChemMedChem. 6, 3, p. 498-504 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Role of GluR2 expression in AMPA-induced toxicity in cultured murine cerebral cortical neurons

    Jensen, J. B., Lund, Trine Meldgaard, Timmermann, D. B., Schousboe, Arne & Pickering, Darryl S, 2001, In : Journal of Neuroscience Research. 65, 3, p. 267-277 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Role of desensitization and subunit expression for kainate receptor-mediated neurotoxicity in murine neocortical cultures

    Jensen, J. B., Schousboe, Arne, Pickering, Darryl S & Pickering, Darryl S, 1999, In : Journal of Neuroscience Research. 55, 2, p. 208-17 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Selective kainate receptor (GluK1) ligands structurally based upon1H-Cyclopentapyrimidin-2,4(1H,3H)-dione: synthesis, molecular modeling, and pharmacological and biostructural characterization

    Venskutonyte, R., Butini, S., Coccone, S. S., Gemma, S., Brindisi, M., Kumar, V., Guarino, E., Maramai, S., Valenti, S., Amir, A., Valades, E. A., Frydenvang, Karla Andrea, Kastrup, Jette Sandholm Jensen, Novellino, E., Campiani, G. & Pickering, Darryl S, 14 Jul 2011, In : Journal of Medicinal Chemistry. 54, 13, p. 4793-4805

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Simple cellemodeller for kommunikation i hjernen

    Schousboe, Arne, Madsen, K. K. & Pickering, Darryl S, 2011, Bioteknologi - en temabog. Gasbjerg, P., Jensen, G. & Sørensen, A. (eds.). Aarhus Danmark: Systime Academic, p. 98-107 10 p.

    Research output: Chapter in Book/Report/Conference proceedingBook chapterEducation

  10. Published

    Structural analysis of the positive AMPA receptor modulators CX516 and Me-CX516 in complex with the GluA2 ligand-binding domain

    Krintel, C., Harpsøe, Kasper, Dorvil, Linda Grønborg, Peters, D., Frydenvang, Karla Andrea, Pickering, Darryl S, Gajhede, Michael & Kastrup, Jette Sandholm Jensen, 2013, In : Acta Crystallographica Section D: Structural Biology. 69, Pt 9, p. 1645-1652 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

ID: 1299533