Darryl S Pickering

Department of Drug Design and Pharmacology

Associate Professor

Molecular and Cellular Pharmacology
Jagtvej 160, 2100 København Ø, 22, Building: C213
- picker@sund.ku.dk
- https://drug.ku.dk/
Phone: +45 35 33 43 42

ORCID: 0000-0001-8687-6094

Publication year:

All

1 - 50 out of 91Page size: 50

Sort by: Title

Published
(S)-2-Amino-3-(5-methyl-3-hydroxyisoxazol-4-yl)propanoic Acid (AMPA) and Kainate Receptor Ligands: Further Exploration of Bioisosteric Replacements, Structural and Biological Investigation. / Brogi, Simone; Brindisi, Marghertia; Butini, Stefania; Kshirsagar, Giridhar; Maramai, Samuele; Chemi, Giulia; Gemma, Sandra; Campiani, Giuseppe; Novellino, Ettore; Fiorenzani, Paolo; Pinassi, Jessica; Aloisi, Anna Maria; Gynther, Mikko; Venskutonyte, Raminta; Han, Liwei; Frydenvang, Karla Andrea ; Kastrup, Jette Sandholm Jensen ; Pickering, Darryl S.
In: Journal of Medicinal Chemistry, Vol. 61, No. 5, 08.03.2018, p. 2124-2130.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
1H-cyclopentapyrimidine-2,4(1H,3H)-dione-related ionotropic glutamate receptors ligands. Structure-activity relationships and identification of potent and selective iGluR5 modulators. / Butini, Stefania; Pickering, Darryl S; Morelli, Elena; Coccone, Salvatore Sanna; Trotta, Francesco; De Angelis, Meri; Guarino, Egeria; Fiorini, Isabella; Campiani, Giuseppe; Novellino, Ettore; Schousboe, Arne; Christensen, Jeppe K; Gemma, Sandra.
In: Journal of Medicinal Chemistry, Vol. 51, No. 20, 2008, p. 6614-8.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
3-Substituted phenylalanines as selective AMPA- and kainate receptor ligands. / Szymanska, Ewa; Pickering, Darryl S ; Nielsen, Birgitte ; Johansen, Tommy N.
In: Bioorganic & Medicinal Chemistry, Vol. 17, No. 17, 2009, p. 6390-401.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
3-hydroxypyridazine 1-oxides as carboxylate bioisosteres : a new series of subtype-selective AMPA receptor agonists. / Greenwood, Jeremy R; Mewett, Ken N; Allan, Robin D; Martín, Belén Ortiz; Pickering, Darryl.
In: Neuropharmacology, Vol. 51, No. 1, 07.2006, p. 52-9.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
4,4-Dimethyl- and diastereomeric 4-hydroxy-4-methyl-(2S)-glutamate analogues display distinct pharmacological profiles at ionotropic glutamate receptors and excitatory amino acid transporters. / Bunch, Lennart ; Pickering, Darryl S; Gefflaut, Thierry; Vinatier, Virginie; Helaine, Virgil; Amir, Ahmad; Nielsen, Birgitte ; Jensen, Anders Asbjørn.
In: ChemMedChem, Vol. 4, No. 11, 2009, p. 1925-1929.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
4-Alkylated homoibotenic acid (HIBO) analogues: versatile pharmacological agents with diverse selectivity profiles towards metabotropic and ionotropic glutamate receptor subtypes. / Madsen, Ulf ; Pickering, Darryl S ; Nielsen, Birgitte ; Bräuner-Osborne, Hans.
In: Neuropharmacology, Vol. 49 Suppl 1, 2005, p. 114-9.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
4-hydroxy-1,2,5-oxadiazol-3-yl moiety as bioisoster of the carboxy function. Synthesis, ionization constants, and molecular pharmacological characterization at ionotropic glutamate receptors of compounds related to glutamate and its homologues. / Lolli, Marco L; Giordano, Cecilia; Pickering, Darryl S; Rolando, Barbara; Hansen, Kasper B; Foti, Antonio; Contreras-Sanz, Alberto; Amir, Ahmad; Fruttero, Roberta; Gasco, Alberto; Nielsen, Birgitte ; Johansen, Tommy N.
In: Journal of Medicinal Chemistry, Vol. 53, No. 10, 2010, p. 4110-8.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
N-(7-(1H-imidazol-1-yl)-2,3-dioxo-6-(trifluoromethyl)-3,4-dihydroquinoxalin-1(2H)-yl)benzamide - a new kainate receptor selective antagonist and analgesic : Synthesis, X-ray crystallography, structure-affinity relationships, in vitro and in vivo pharmacology. / Møllerud, Stine ; Hansen, Rie B; Pallesen, Jakob S; Temperini, Piero; Pasini, Diletta; Bornholdt, Jan; Nielsen, Birgitte ; Mamedova, Esmira; Chalupnik, Paulina; Paternain, Ana V; Lerma, Juan; Del Castillo, Marta Diaz ; Andreasen, Jesper T ; Frydenvang, Karla ; Kastrup, Jette Sandholm ; Johansen, Tommy N ; Pickering, Darryl S.
In: ACS Chemical Neuroscience, Vol. 10, 2019, p. 4685-4695.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
In vitro and in vivo effects of a novel dimeric inhibitor of PSD‐95 on excitotoxicity and functional recovery after experimental traumatic brain injury. / Sommer, Jens Bak; Bach, Anders ; Rytter, Hana Malá ; Strømgaard, Kristian ; Mogensen, Jesper ; Pickering, Darryl S.
In: European Journal of Neuroscience, Vol. 45, No. 2, 20.01.2017, p. 238-248.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
A new phenylalanine derivative acts as an antagonist at the AMPA receptor GluA2 and introduces partial domain closure : Synthesis, resolution, pharmacology, and crystal structure. / Szymanska, Ewa; Frydenvang, Karla; Contreras-Sanz, Alberto; Pickering, Darryl S; Frola, Elena; Serafimoska, Zorica; Nielsen, Birgitte ; Kastrup, Jette Sandholm ; Johansen, Tommy Nørskov.
In: Journal of Medicinal Chemistry, Vol. 54, No. 20, 04.10.2011, p. 7289-7298.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
A pharmacological profile of the high-affinity GluK5 kainate receptor. / Møllerud, Stine ; Kastrup, Jette Sandholm Jensen ; Pickering, Darryl S.
In: European Journal of Pharmacology, Vol. 788, 2016, p. 315-320.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
A tetrazolyl-substituted subtype-selective AMPA receptor agonist. / Vogensen, Stine Byskov; Frydenvang, Karla Andrea; Greenwood, Jeremy R.; Postorino, Giovanna; Nielsen, Birgitte ; Pickering, Darryl Scott; Ebert, Bjarke; Bølcho, Ulrik; Egebjerg, Jan; Gajhede, Michael ; Kastrup, Jette Sandholm Jensen ; Johansen, Tommy Nørskov ; Clausen, Rasmus Prætorius ; Krogsgaard-Larsen, Povl.
In: Journal of Medicinal Chemistry, Vol. 50, No. 10, 2007, p. 2408-2414.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Analogues of 3-Hydroxyisoxazole-Containing Glutamate Receptor Ligands Based on the 3-Hydroxypyrazole-Moiety: Design, Synthesis and Pharmacological Characterization. / Jørgensen, Lars; Nielsen, Birgitte ; Pickering, Darryl S ; Kristensen, Anders Skov ; Frydenvang, Karla Andrea ; Madsen, Ulf ; Clausen, Rasmus Prætorius.
In: Neurochemical Research, Vol. 39, No. 10, 2014, p. 1895-1905.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Aryl- and heteroaryl-substituted phenylalanines as AMPA receptor ligands. / Szymańska, Ewa; Chałupnik, Paulina; Johansen, Tommy Nørskov ; Nielsen, Birgitte; Cuñado Moral, Ana Maria; Pickering, Darryl S; Kieć-Kononowicz, Katarzyna.
In: Chemical Biology & Drug Design, Vol. 90, 01.12.2017, p. 1271-1281.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Augmentation of Anticancer Drug Efficacy in Murine Hepatocellular Carcinoma Cells by a Peripherally Acting Competitive N-Methyl-d-aspartate (NMDA) Receptor Antagonist. / Gynther, Mikko; Proietti Silvestri, Ilaria; Hansen, Jacob C; Hansen, Kasper B; Malm, Tarja; Ishchenko, Yevheniia; Larsen, Younes; Han, Liwei; Kayser, Silke; Auriola, Seppo; Petsalo, Aleksanteri; Nielsen, Birgitte ; Pickering, Darryl S ; Bunch, Lennart.
In: Journal of Medicinal Chemistry, Vol. 60, No. 23, 14.12.2017, p. 9885-9904.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Binding Mode of an α-Amino Acid-Linked Quinoxaline-2,3-dione Analogue at Glutamate Receptor Subtype GluK1. / Demmer, Charles S; Møller, Charlotte; Brown, Patricia M G E; Han, Liwei; Pickering, Darryl S ; Nielsen, Birgitte; Bowie, Derek; Frydenvang, Karla ; Kastrup, Jette S ; Bunch, Lennart.
In: A C S Chemical Neuroscience, Vol. 6, 09.04.2015, p. 845-854.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Binding and functional pharmacological characteristics of gepant-type antagonists in rat brain and mesenteric arteries. / Sheykhzade, Majid; Amandi, Nilofar; Pla, Monica Vidal; Abdolalizadeh, Bahareh; Sams, Anette; Warfvinge, Karin; Edvinsson, Lars ; Pickering, Darryl S.
In: Vascular Pharmacology, Vol. 90, 10.02.2017, p. 36-43.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Binding site and interlobe interactions of the ionotropic glutamate receptor GluK3 ligand binding domain revealed by high resolution crystal structure in complex with (S)-glutamate. / Venskutonyte, Raminta; Frydenvang, Karla ; Gajhede, Michael ; Bunch, Lennart ; Pickering, Darryl S ; Kastrup, Jette Sandholm.
In: Journal of Structural Biology, Vol. 176, No. 3, 12.2011, p. 307-314.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Biostructural and pharmacological studies of bicyclic analogues of the 3-isoxazolol glutamate receptor agonist ibotenic acid. / Frydenvang, Karla Andrea ; Pickering, Darryl S; Greenwood, Jeremy R; Krogsgaard-Larsen, Niels; Brehm, Lotte; Nielsen, Birgitte; Vogensen, Stine Byskov; Hald, Helle; Kastrup, Jette Sandholm ; Krogsgaard-Larsen, Povl ; Clausen, Rasmus Prætorius.
In: Journal of Medicinal Chemistry, Vol. 53, No. 23, 10.11.2010, p. 8354-8361.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Blood-brain barrier permeability and brain uptake mechanism of kainic Acid and dihydrokainic Acid. / Gynther, Mikko; Petsalo, Aleksanteri; Hansen, Steen Honoré; Bunch, Lennart ; Pickering, Darryl S.
In: Neurochemical Research, Vol. 40, No. 3, 03.2015, p. 542-549.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Chemo-enzymatic synthesis of (2S,4R)-2-amino-4-(3-(2,2-diphenylethylamino)-3-oxopropyl)pentanedioic acid : a novel selective inhibitor of human excitatory amino acid transporter subtype 2. / Sagot, Emanuelle; Jensen, Anders A.; Pickering, Darryl S; Pu, Xiaosui; Umberti, Michelle; Stensbøl, Tine B.; Nielsen, Birgitte; Assaf, Zeinab; Aboab, Bétina; Bolte, Jean; Gefflaut, Thierry; Bunch, Lennart.
In: Journal of Medicinal Chemistry, Vol. 51, No. 14, 2008, p. 4085-4092.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Chemo-enzymatic synthesis of a series of 2,4-syn-functionalized (S)-glutamate analogues: new insight into the structure-activity relation of ionotropic glutamate receptor subtypes 5, 6, and 7. / Sagot, Emanuelle; Pickering, Darryl S; Pu, Xiaosui; Umberti, Michelle; Stensbøl, Tine B; Nielsen, Birgitte; Chapelet, Marion; Bolte, Jean; Gefflaut, Thierry; Bunch, Lennart.
In: Journal of Medicinal Chemistry, Vol. 51, No. 14, 2008, p. 4093-103.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Chemo-enzymatic synthesis of new 2,4-syn-functionalized (S)-glutamate analogues and structure-activity relationship studies at ionotropic glutamate receptors and excitatory amino acid transporters. / Assaf, Z.; Larsen, Anja Probst; Venskutonyte, Raminta; Han, Liwei; Abrahamsen, Bjarke; Nielsen, Birgitte ; Gajhede, Michael ; Kastrup, Jette Sandholm ; Jensen, Anders A.; Pickering, Darryl S ; Frydenvang, Karla ; Gefflaut, T; Bunch, Lennart.
In: Journal of Medicinal Chemistry, Vol. 56, No. 4, 2013, p. 1614-1628.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Cognitive enhancing effects of an AMPA receptor positive modulator on place learning in mice. / Rytter, Hana Malá; Chen, Yuxia; Worm, Vivi Hu; Kure, Julie; Kaae, Birgitte H.; Madsen, Ulf; Badolo, Lassina; Pickering, Darryl S ; Mogensen, Jesper.
In: Behavioural Brain Research, Vol. 226, No. 1, 2012, p. 18-25.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Computeren viser vejen til et nyt potentielt lægemiddel. / Harpsøe, Kasper; Kaae, Birgitte Høiriis; Balle, Thomas; Pickering, Darryl S ; Kastrup, Jette Sandholm Jensen.
In: Lægemiddelforskning, 2008, p. 28-30.
Research output: Contribution to journal › Journal article › Communication
Published
Convergent synthesis and pharmacology of substituted tetrazolyl-2-amino-3-(3-hydroxy-5-methyl-4-isoxazolyl)propionic acid analogues. / Vogensen, SB; Clausen, Rasmus Prætorius; Greenwood, JR; Johansen, Tommy Nørskov ; Pickering, DS ; Nielsen, Birgitte; Ebert, Barke; Krogsgaard-Larsen, P.
In: Journal of Medicinal Chemistry, Vol. 48, No. 9, 05.05.2005, p. 3438-3442.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Crystal structure and pharmacological characterization of a novel N-methyl-D-aspartate (NMDA) receptor antagonist at the GluN1 glycine binding site. / Kvist, Trine; Steffensen, Thomas Bielefeldt; Greenwood, Jeremy R; Mehrzad Tabrizi, Fatemeh; Hansen, Kasper Bø; Gajhede, Michael ; Pickering, Darryl S; Traynelis, Stephen F; Kastrup, Jette Sandholm ; Bräuner-Osborne, Hans.
In: The Journal of Biological Chemistry, Vol. 288, 2013, p. 33124-35.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
D-aspartate and NMDA, but not L-aspartate, block AMPA receptors in rat hippocampal neurons. / Gong, Xiang-Qun; Frandsen, Anne; Lu, Wei-Yang; Wan, Yudi; Zabek, Rebecca L; Pickering, Darryl; Bai, Donglin.
In: British Journal of Pharmacology, Vol. 145, No. 4, 2005, p. 449-59.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Design and Synthesis of 2,3-trans-Proline Analogs as Ligands for the Ionotropic Glutamate Receptors and the Excitatory Amino Acid Transporters. / Poulie, Christian Bernard Matthijs; Alcaide Lopez, Anna; Krell-Jørgensen, Mikkel Poul; Larsen, Younes; Astier, Eloi; Bjørn-Yoshimoto, Walden E.; Yi, Feng; Syrenne, Jed T; Storgaard, Morten; Nielsen, Birgitte ; Frydenvang, Karla Andrea ; Jensen, Anders A.; Hansen, Kasper B; Pickering, Darryl S ; Bunch, Lennart.
In: A C S Chemical Neuroscience, Vol. 10, No. 6, 19.06.2019, p. 2989-3007.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Design and Synthesis of a Series of L-trans-4-Substituted Prolines as Selective Antagonists for the Ionotropic Glutamate Receptors Including Functional and X-ray Crystallographic Studies of New Subtype Selective Kainic Acid Receptor Subtype 1 (GluK1) Antagonist (2S,4R)-4-(2-Carboxyphenoxy)pyrrolidine-2-carboxylic Acid. / Krogsgaard-Larsen, Niels; Delgar, Claudia; Koch, Karina; Brown, Patricia M G E; Møller, Charlotte; Han, Liwei; Huynh, Tri Hien Viet; Hansen, Stinne Wessel; Nielsen, Birgitte; Bowie, Derek; Pickering, Darryl S ; Kastrup, Jette Sandholm Jensen ; Frydenvang, Karla Andrea ; Bunch, Lennart.
In: Journal of Medicinal Chemistry, Vol. 60, No. 1, 2017, p. 441-457.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Design and characterization of dimeric ligands cross-linking two identical modulatory AMPA receptor sites. / Kaae, Birgitte H.; Harpsoe, Kasper; Sanz, Alberto Contreras; Pickering, Darryl S.; Sauerberg, Per; Clausen, Rasmus Prætorius ; Kastrup, Jette S.; Liljefors, Tommy; Madsen, Ulf.
In: American Chemical Society. Abstracts of Papers (at the National Meeting), Vol. 234, 19.08.2007.
Research output: Contribution to journal › Conference abstract in journal › Research
Published
Design, synthesis and in vitro pharmacology of GluK1 and GluK3 antagonists. Studies towards the design of subtype-selective antagonists through 2-carboxyethyl-phenylalanines with substituents interacting with non-conserved residues in the GluK binding sites. / Sköld, Niklas; Nielsen, Birgitte; Olsen, Jakob; Han, Liwei; Olsen, Lars; Madsen, Ulf ; Kristensen, Jesper Langgaard ; Pickering, Darryl S ; Johansen, Tommy N.
In: Bioorganic & Medicinal Chemistry, Vol. 22, No. 19, 02.08.2014, p. 5368-5377.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Design, synthesis and structure-activity relationships of novel phenylalanine-based amino acids as kainate receptors ligands. / Szymańska, Ewa; Chałupnik, Paulina; Szczepańska, Katarzyna; Moral, Ana Maria Cuñado; Pickering, Darryl S ; Nielsen, Birgitte ; Johansen, Tommy Nørskov; Kieć-Kononowicz, Kieć-Kononowicz.
In: Bioorganic & Medicinal Chemistry Letters, Vol. 26, No. 22, 2016, p. 5568-5572.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Differential role of AMPA receptors in mouse tests of antidepressant and anxiolytic action. / Andreasen, Jesper T; Fitzpatrick, Ciaran M; Larsen, Maria; Skovgaard, Lars; Nielsen, Simon D; Clausen, Rasmus P; Troelsen, Karin; Pickering, Darryl S.
In: Brain Research, Vol. 1601, 19.03.2015, p. 117-26.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Discovery of a New Class of Ionotropic Glutamate Receptor Antagonists by the Rational Design of (2S,3R)-3-(3-Carboxyphenyl)-pyrrolidine-2-carboxylic Acid. / Larsen, Ann Møller; Venskutonyte, Raminta; Valadés, Elena Antón; Nielsen, Birgitte ; Pickering, Darryl S ; Bunch, Lennart.
In: ACS Chemical Neuroscience, Vol. 2, No. 2, 04.11.2011, p. 107-114.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Does increasing the ratio of AMPA-to-NMDA receptor mediated neurotransmission engender antidepressant action? Studies in the mouse forced swim and tail suspension tests. / Andreasen T., Jesper; Gynther, Mikko Otto Oskari; Rygaard, Allan; Bøgelund, Trine; Nielsen, Simon Dalsgaard; Clausen, Rasmus Prætorius ; Mogensen, Jesper ; Pickering, Darryl S.
In: Neuroscience Letters, Vol. 546, 2013, p. 6-10.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Effect of synthetic and natural phospholipids on N-acylphosphatidylethanolamine-hydrolyzing phospholipase D activity. / Petersen, Gitte; Pedersen, Anders H; Pickering, Darryl S; Begtrup, Mikael; Hansen, Harald S.
In: Chemistry and Physics of Lipids, Vol. 162, No. 1-2, 2009, p. 53-61.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Effects of dimeric PSD-95 inhibition on excitotoxic cell death and outcome after controlled cortical impact in rats : PSD-95 inhibition in experimental TBI. / Sommer, Jens Bak; Bach, Anders ; Rytter, Hana Malá; Gynther, Mikko; Bjerre, Ann-Sofie; Gram, Marie Gajhede; Marschner, Linda; Strømgaard, Kristian ; Mogensen, Jesper ; Pickering, Darryl S.
In: Neurochemical Research, Vol. 42, No. 12, 2017, p. 3401-3413.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Effects of sertraline, duloxetine, vortioxetine, and idazoxan in the rat affective bias test. / Refsgaard, Louise Konradsen; Haubro, Kia; Pickering, Darryl S; Stuart, Sarah; Robinson, Emma; Andreasen T., Jesper.
In: Psychopharmacology, Vol. 233, No. 21, 14.10.2016, p. 3763-3770.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Effects of the dimeric PSD-95 inhibitor UCCB01-144 in mouse models of pain, cognition and motor function. / Andreasen, Jesper T; Nasser, Arafat; Caballero-Puntiverio, Maitane; Sahlholt, Maj; Bach, Anders; Gynther, Mikko; Strømgaard, Kristian ; Pickering, Darryl S.
In: European Journal of Pharmacology, Vol. 780, 05.06.2016, p. 166-73.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Effects of the dimeric PSD-95 inhibitor UCCB01-144 on functional recovery after fimbria-fornix transection in rats. / Sommer, Jens Bak; Bach, Anders ; Malá, Hana ; Strømgaard, Kristian ; Mogensen, Jesper ; Pickering, Darryl S.
In: Pharmacology, Biochemistry and Behavior, Vol. 161, 10.2017, p. 62-67.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Enthalpy-Entropy Compensation in the Binding of Modulators at Ionotropic Glutamate Receptor GluA2. / Krintel, Christian; Francotte, Pierre; Pickering, Darryl S; Juknaite, Lina; Pøhlsgaaard, Jakob; Olsen, Lars; Frydenvang, Karla Andrea; Goffin, Eric; Pirotte, Bernard; Kastrup, Jette Sandholm Jensen.
In: Biophysical Journal, Vol. 110, No. 11, 2016, p. 2397-2406.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Exploring the GluR2 ligand-binding core in complex with the bicyclical AMPA analogue (S)-4-AHCP. / Nielsen, Bettina B; Pickering, Darryl S; Greenwood, Jeremy R; Brehm, Lotte; Gajhede, Michael ; Schousboe, Arne ; Kastrup, Jette S.
In: FEBS Journal, Vol. 272, No. 7, 2005, p. 1639-48.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Forster Resonance Energy Transfer (FRET) Analysis of Dual CFP/YFP Labeled AMPA Receptors Reveals Structural Rearrangement within the C-Terminal Domain during Receptor Activation. / Zachariassen, Linda Grønborg; Katchan, Mila; Plested, Andrew; Pickering, Darryl S ; Kristensen, Anders Skov.
2014.
Research output: Contribution to conference › Conference abstract for conference › Research › peer-review
Published
Full domain closure of the ligand-binding core of the ionotropic glutamate receptor iGluR5 induced by the high affinity agonist dysiherbaine and the functional antagonist 8,9-dideoxyneodysiherbaine. / Frydenvang, Karla Andrea; Lash, L Leanne; Naur, Peter; Postila, Pekka A; Pickering, Darryl S; Smith, Caleb M; Gajhede, Michael; Sasaki, Makoto; Sakai, Ryuichi; Pentikäinen, Olli T; Swanson, Geoffrey T; Kastrup, Jette Sandholm.
In: Journal of Biological Chemistry, Vol. 284, No. 21, 2009, p. 14219-14229.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
GABA transporter localization to lipid raft membrane microdomains in neurons and astrocytes. / Madsen, Karsten Kirkegaard; Pickering, Darryl S; Hansen, G.H.; Danielsen, E.M.; Larsson, Orla Miller; Schousboe, Arne.
In: Journal of Neurochemistry, Vol. 102, No. s1, 2007, p. 46.
Research output: Contribution to journal › Conference abstract in journal › Research
Published
Investigation of antidepressant-like and anxiolytic-like actions and cognitive and motor side effects of four N-methyl-D-aspartate receptor antagonists in mice. / Refsgaard, Louise Konradsen; Pickering, Darryl S ; Andreasen T., Jesper.
In: Behavioural Pharmacology, Vol. 28, No. 1, 01.02.2017, p. 37-47.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Investigation of the presence and antinociceptive function of muscarinic acetylcholine receptors in the African naked mole-rat (Heterocephalus glaber). / Jørgensen, Kristine B.; Krogh-Jensen, Karen; Pickering, Darryl S; Kanui, Titus; Abelson, Klas.
In: Journal of Comparative Physiology A. Sensory, neural, and behavioral physiology, Vol. 202, No. 1, 01.01.2016, p. 7-15.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Ionotropic glutamate-like receptor d2 binds D-serine and glycine. / Naur, Peter; Hansen, Kasper Bø; Kristensen, Anders Skov; Dravid, Shashank M.; Pickering, Darryl Scott; Olsen, Lars; Vestergaard, Bente; Egebjerg, Jan; Gajhede, Michael; Traynelis, Stephen F.; Kastrup, Jette Sandholm Jensen.
In: Proceedings of the National Academy of Science of the United States of America, Vol. 104, No. 35, 2007, p. 14116-14121.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
L-Asp is a useful tool in the purification of the ionotropic glutamate receptor A2 ligand-binding domain. / Krintel, Christian; Frydenvang, Karla; Ceravalls de Rabassa, Anna; Kaern, Anne Mette; Gajhede, Michael ; Pickering, Darryl S ; Kastrup, Jette S.
In: F E B S Journal, 27.03.2014, p. 2422–2430.
Research output: Contribution to journal › Journal article › Research › peer-review

Previous 1 2 Next

ID: 1299533

Darryl S Pickering

Molecular and Cellular Pharmacology

Most downloads

Investigation of the presence and antinociceptive function of muscarinic acetylcholine receptors in the African naked mole-rat (Heterocephalus glaber)