Darryl S Pickering
Darryl S Pickering

Associate Professor


  1. Published

    Structural proof of a dimeric positive modulator bridging two identical AMPA receptor-binding sites

    Kaae, B. H., Harpsøe, Kasper, Kastrup, Jette Sandholm Jensen, Sanz, A. C., Pickering, Darryl S, Metzler, B., Clausen, Rasmus Prætorius, Gajhede, Michael, Sauerberg, P., Liljefors, T. & Madsen, Ulf, 2007, In : Chemistry & Biology. 14, 11, p. 1294-303 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Published

    Structural rearrangement of the intracellular domains during AMPA receptor activation

    Dorvil, Linda Grønborg, Katchan, L., Jensen, A. G., Pickering, Darryl S, Plested, A. & Kristensen, Anders Skov, 2016, In : Proceedings of the National Academy of Sciences USA (PNAS). 113, 27, p. E3950-E3959 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Structure and affinity of two bicyclic glutamate analogues at AMPA and kainate receptors

    Møllerud, Stine, Pinto, A., Marconi, L., Frydenvang, Karla Andrea, Thorsen, Thor Seneca, Laulumaa, S. K., Venskutonyte, R., Winther, N., Cunado Moral, A. M., Tamborini, L., Conti, P., Pickering, Darryl S & Kastrup, Jette Sandholm Jensen, 2017, In : A C S Chemical Neuroscience. 8, 9, p. 2056-2064 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Structure of a High-Affinity Kainate Receptor: GluK4 Ligand-Binding Domain Crystallized with Kainate

    Kristensen, O., Kristensen, L. B., Møllerud, Stine, Frydenvang, Karla Andrea, Pickering, Darryl S & Kastrup, Jette Sandholm Jensen, 2016, In : Structure. 24, 9, p. 1582-1589 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Structure-Activity Relationship Study of Ionotropic Glutamate Receptor Antagonist (2S,3R)-3-(3-Carboxyphenyl)pyrrolidine-2-carboxylic Acid

    Krogsgaard-Larsen, N., Storgaard, M., Møller, C., Demmer, C. S., Hansen, J., Han, L., Monrad, R. N., Nielsen, Birgitte, Tapken, D., Pickering, Darryl S, Kastrup, Jette Sandholm Jensen, Frydenvang, Karla Andrea & Bunch, Lennart, 2015, In : Journal of Medicinal Chemistry. 58, 15, p. 6131-50 20 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published
  7. Published

    Studies on Aryl-Substituted Phenylalanines: Synthesis, Activity, and Different Binding Modes at AMPA Receptors

    Szymanska, E., Frydenvang, Karla Andrea, Pickering, Darryl S, Krintel, C., Nielsen, Birgitte, Kooshki, A., Dorvil, Linda Grønborg, Olsen, L., Kastrup, Jette Sandholm Jensen & Johansen, Tommy Nørskov, 2016, In : Journal of Medicinal Chemistry. 59, 1, p. 448-461 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Studies on an (S)-2-amino-3-(3-hydroxy-5-methyl-4-isoxazolyl)propionic acid (AMPA) receptor antagonist IKM-159: asymmetric synthesis, neuroactivity, and structural characterization

    Juknaite, L., Sugamata, Y., Tokiwa, K., Ishikawa, Y., Takamizawa, S., Eng, A., Sakai, R., Pickering, Darryl S, Frydenvang, Karla Andrea, Swanson, G. T., Kastrup, Jette Sandholm Jensen & Oikawa, M., 2013, In : Journal of Medicinal Chemistry. 56, 6, p. 2283-2293

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Synthesis and Pharmacological Characterization of the Selective GluK1 Radioligand (S)-2-Amino-3-(6-[3H]-2,4-dioxo-3,4-dihydrothieno[3,2-d]pyrimidin-1(2H)-yl)propanoic acid ([3H]-NF608)

    Alcaide, A., Marconi, L., Marek, A., Haym, I., Nielsen, Birgitte, Møllerud, Stine, Jensen, M., Conti, P., Pickering, Darryl S & Bunch, Lennart, 2016, In : MedChemComm. 7, p. 2136-2144 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Systemic and Brain Pharmacokinetics of Perforin Inhibitor Prodrugs

    Gynther, M., Pickering, Darryl S, Spicer, J., Denny, W. & Huttunen, K., 2016, In : Molecular Pharmaceutics. 13, 7, p. 2484-2491 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

ID: 1299533