Darryl S Pickering

Darryl S Pickering

Associate Professor


  1. Published

    Chemo-enzymatic synthesis of new 2,4-syn-functionalized (S)-glutamate analogues and structure-activity relationship studies at ionotropic glutamate receptors and excitatory amino acid transporters. / Assaf, Z.; Larsen, Anja Probst; Venskutonyte, Raminta; Han, Liwei; Abrahamsen, Bjarke; Nielsen, Birgitte; Gajhede, Michael; Kastrup, Jette Sandholm; Jensen, Anders A.; Pickering, Darryl S; Frydenvang, Karla ; Gefflaut, T; Bunch, Lennart.

    In: Journal of Medicinal Chemistry, Vol. 56, No. 4, 2013, p. 1614-1628.

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Published

    Cognitive enhancing effects of an AMPA receptor positive modulator on place learning in mice. / Rytter, Hana Malá; Chen, Yuxia; Worm, Vivi Hu; Kure, Julie; Kaae, Birgitte H.; Madsen, Ulf; Badolo, Lassina; Pickering, Darryl S; Mogensen, Jesper.

    In: Behavioural Brain Research, Vol. 226, No. 1, 2012, p. 18-25.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Computeren viser vejen til et nyt potentielt lægemiddel. / Harpsøe, Kasper; Kaae, Birgitte Høiriis; Balle, Thomas; Pickering, Darryl S; Kastrup, Jette Sandholm Jensen.

    In: Lægemiddelforskning, 2008, p. 28-30.

    Research output: Contribution to journalJournal articleCommunication

  4. Published

    Crystal structure and pharmacological characterization of a novel N-methyl-D-aspartate (NMDA) receptor antagonist at the GluN1 glycine binding site. / Kvist, Trine; Steffensen, Thomas Bielefeldt; Greenwood, Jeremy R; Mehrzad Tabrizi, Fatemeh; Hansen, Kasper Bø; Gajhede, Michael; Pickering, Darryl S; Traynelis, Stephen F; Kastrup, Jette Sandholm; Bräuner-Osborne, Hans.

    In: The Journal of Biological Chemistry, Vol. 288, 2013, p. 33124-35.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Design and Synthesis of 2,3-trans-Proline Analogs as Ligands for the Ionotropic Glutamate Receptors and the Excitatory Amino Acid Transporters. / Poulie, Christian Bernard Matthijs; Alcaide Lopez, Anna; Krell-Jørgensen, Mikkel Poul; Larsen, Younes; Astier, Eloi; Bjørn-Yoshimoto, Walden E.; Yi, Feng; Syrenne, Jed T; Storgaard, Morten; Nielsen, Birgitte; Frydenvang, Karla Andrea; Jensen, Anders A.; Hansen, Kasper B; Pickering, Darryl S; Bunch, Lennart.

    In: A C S Chemical Neuroscience, Vol. 10, No. 6, 19.06.2019, p. 2989-3007.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Design and Synthesis of a Series of L-trans-4-Substituted Prolines as Selective Antagonists for the Ionotropic Glutamate Receptors Including Functional and X-ray Crystallographic Studies of New Subtype Selective Kainic Acid Receptor Subtype 1 (GluK1) Antagonist (2S,4R)-4-(2-Carboxyphenoxy)pyrrolidine-2-carboxylic Acid. / Krogsgaard-Larsen, Niels; Delgar, Claudia; Koch, Karina; Brown, Patricia M G E; Møller, Charlotte; Han, Liwei; Huynh, Tri Hien Viet; Hansen, Stinne Wessel; Nielsen, Birgitte; Bowie, Derek; Pickering, Darryl S; Kastrup, Jette Sandholm Jensen; Frydenvang, Karla Andrea; Bunch, Lennart.

    In: Journal of Medicinal Chemistry, Vol. 60, No. 1, 2017, p. 441-457.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Design and characterization of dimeric ligands cross-linking two identical modulatory AMPA receptor sites. / Kaae, Birgitte H.; Harpsoe, Kasper; Sanz, Alberto Contreras; Pickering, Darryl S.; Sauerberg, Per; Clausen, Rasmus Prætorius; Kastrup, Jette S.; Liljefors, Tommy; Madsen, Ulf.

    In: American Chemical Society. Abstracts of Papers (at the National Meeting), Vol. 234, 19.08.2007.

    Research output: Contribution to journalConference abstract in journalResearch

  8. Published
  9. Published

    Design, synthesis and structure-activity relationships of novel phenylalanine-based amino acids as kainate receptors ligands. / Szymańska, Ewa; Chałupnik, Paulina; Szczepańska, Katarzyna; Moral, Ana Maria Cuñado; Pickering, Darryl S; Nielsen, Birgitte; Johansen, Tommy Nørskov; Kieć-Kononowicz, Kieć-Kononowicz.

    In: Bioorganic & Medicinal Chemistry Letters, Vol. 26, No. 22, 2016, p. 5568-5572.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Differential role of AMPA receptors in mouse tests of antidepressant and anxiolytic action. / Andreasen, Jesper T; Fitzpatrick, Ciaran M; Larsen, Maria; Skovgaard, Lars; Nielsen, Simon D; Clausen, Rasmus P; Troelsen, Karin; Pickering, Darryl S.

    In: Brain Research, Vol. 1601, 19.03.2015, p. 117-26.

    Research output: Contribution to journalJournal articleResearchpeer-review

ID: 1299533