Darryl S Pickering

Darryl S Pickering

Associate Professor


  1. Published

    Structure of a High-Affinity Kainate Receptor: GluK4 Ligand-Binding Domain Crystallized with Kainate

    Kristensen, O., Kristensen, L. B., Frantsen, Stine Møllerud, Frydenvang, Karla Andrea, Pickering, Darryl S & Kastrup, Jette Sandholm Jensen, 2016, In : Structure. 24, 9, p. 1582-1589 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Published

    Structure-Activity Relationship Study of Ionotropic Glutamate Receptor Antagonist (2S,3R)-3-(3-Carboxyphenyl)pyrrolidine-2-carboxylic Acid

    Krogsgaard-Larsen, N., Storgaard, M., Møller, C., Demmer, C. S., Hansen, J., Han, L., Monrad, R. N., Nielsen, Birgitte, Tapken, D., Pickering, Darryl S, Kastrup, Jette Sandholm Jensen, Frydenvang, Karla Andrea & Bunch, Lennart, 2015, In : Journal of Medicinal Chemistry. 58, 15, p. 6131-50 20 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Studies on Aryl-Substituted Phenylalanines: Synthesis, Activity, and Different Binding Modes at AMPA Receptors

    Szymanska, E., Frydenvang, Karla Andrea, Pickering, Darryl S, Krintel, C., Nielsen, Birgitte, Kooshki, A., Dorvil, Linda Grønborg, Olsen, L., Kastrup, Jette Sandholm Jensen & Johansen, Tommy Nørskov, 2016, In : Journal of Medicinal Chemistry. 59, 1, p. 448-461 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Studies on an (S)-2-amino-3-(3-hydroxy-5-methyl-4-isoxazolyl)propionic acid (AMPA) receptor antagonist IKM-159: asymmetric synthesis, neuroactivity, and structural characterization

    Juknaite, L., Sugamata, Y., Tokiwa, K., Ishikawa, Y., Takamizawa, S., Eng, A., Sakai, R., Pickering, Darryl S, Frydenvang, Karla Andrea, Swanson, G. T., Kastrup, Jette Sandholm Jensen & Oikawa, M., 2013, In : Journal of Medicinal Chemistry. 56, 6, p. 2283-2293

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Synthesis and Pharmacological Characterization of the Selective GluK1 Radioligand (S)-2-Amino-3-(6-[3H]-2,4-dioxo-3,4-dihydrothieno[3,2-d]pyrimidin-1(2H)-yl)propanoic acid ([3H]-NF608)

    Alcaide, A., Marconi, L., Marek, A., Haym, I., Nielsen, Birgitte, Frantsen, Stine Møllerud, Jensen, M., Conti, P., Pickering, Darryl S & Bunch, Lennart, 2016, In : MedChemComm. 7, p. 2136-2144 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Systemic and Brain Pharmacokinetics of Perforin Inhibitor Prodrugs

    Gynther, M., Pickering, Darryl S, Spicer, J., Denny, W. & Huttunen, K., 2016, In : Molecular Pharmaceutics. 13, 7, p. 2484-2491 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    The Presence of Calcitonin Gene-Related Peptide and Its Receptors in Rat, Pig and Human Brain: Species Differences in Calcitonin Gene-Related Peptide Pharmacology

    Warfvinge, K., Edvinsson, Lars, Pickering, Darryl S & Sheykhzade, Majid, 1 Dec 2019, In : Pharmacology. 104, p. 332-341 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Tweaking subtype-selectivity and agonist efficacy at (S)-2-amino-3-(3-hydroxy-5-methyl-isoxazol-4-yl)propionic acid (AMPA) receptors in a small series of BnTetAMPA analogues

    Wang, S., Larsen, Y., Navarrete, C. V., Jensen, Anders A., Nielsen, Birgitte, Al-Musaed, A., Frydenvang, Karla Andrea, Kastrup, Jette Sandholm Jensen, Pickering, Darryl S & Clausen, Rasmus Prætorius, 2016, In : Journal of Medicinal Chemistry. 59, 5, p. 2244-2254 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    UCCB01-125, a dimeric inhibitor of PSD-95, reduces inflammatory pain without disrupting cognitive or motor performance: Comparison with the NMDA receptor antagonist MK-801

    Andreasen T., Jesper, Bach, Anders, Gynther, M., Nasser, A., Mogensen, Jesper, Strømgaard, Kristian & Pickering, Darryl S, Apr 2013, In : Neuropharmacology. 67, p. 193-200 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Use of the 4-Hydroxy-Triazole Moiety as a Bioisosteric Tool for the Development of Ionotropic Glutamate Receptor Ligands

    Sainas, S., Temperini, P., Farnsworth, J. C., Yi, F., Frantsen, Stine Møllerud, Jensen, Anders A., Nielsen, Birgitte, Kastrup, Jette Sandholm Jensen, Hansen, K. B., Boschi, D., Pickering, Darryl S, Clausen, Rasmus Prætorius & Lolli, M., 9 May 2019, In : Journal of Medicinal Chemistry. 62, p. 4467-4482 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

ID: 1299533