Employees – University of Copenhagen

David E. Gloriam

David E. Gloriam

Associate Professor


  1. 2015
  2. Published

    Identification and characterization of small molecular NPR-B receptor antagonists. / Andresen, Henriette; Moltzau, Lise; Fagerheim, Steffen; Gloriam, David; Bach, Trond; Levy, Finn.

    In: BMC Pharmacology and Toxicology, Vol. 16, No. Suppl 1, 01.01.2015, p. A70.

    Research output: Contribution to journalJournal articleCommunication

  3. Published

    Creating a specialist protein resource network: a meeting report for the protein bioinformatics and community resources retreat. / Babbitt, Patricia C.; Bagos, Pantelis G.; Bairoch, Amos; Bateman, Alex; Chatonnet, Arnaud; Chen, Mark Jinan; Craik, David J.; Finn, Robert D.; Gloriam, David; Haft, Daniel H.; Henrissat, Bernard; Holliday, Gemma L.; Isberg, Vignir; Kaas, Quentin; Landsman, David; Lenfant, Nicolas; Manning, Gerard; Nagano, Nozomi; Srinivasan, Narayanaswamy; O’Donovan, Claire; Pruitt, Kim D.; Sowdhamini, Ramanathan; Rawlings, Neil D.; Saier, Milton H.; Sharman, Joanna L.; Spedding, Michael; Tsirigos, Konstantinos D.; Vastermark, Ake; Vriend, Gerrit.

    In: Database, Vol. 2015, 18.05.2015, p. 1-5.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    A new crystal structure fragment-based pharmacophore method for G protein-coupled receptors. / Fidom, Kimberley; Isberg, Vignir; Hauser, Alexander Sebastian; Mordalski, Stefan; Lehto, Thomas; Bojarski, Andrzej J; Gloriam, David E.

    In: Methods, Vol. 71, 01.2015, p. 104-112.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Selective Negative Allosteric Modulation Of Metabotropic Glutamate Receptors - A Structural Perspective of Ligands and Mutants. / Harpsøe, Kasper; Isberg, Vignir; Tehan, Benjamin G; Weiss, Dahlia; Arsova, Angela; Marshall, Fiona H; Bräuner-Osborne, Hans; Gloriam, David E.

    In: Scientific Reports, Vol. 5, 13869, 11.09.2015, p. 1-11.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Generic GPCR residue numbers - aligning topology maps while minding the gaps. / Isberg, Vignir; de Graaf, Chris; Bortolato, Andrea; Cherezov, Vadim; Katritch, Vsevolod; Marshall, Fiona H; Mordalski, Stefan; Pin, Jean-Philippe; Stevens, Raymond C; Vriend, Gerrit; Gloriam, David E.

    In: Trends in Pharmacological Sciences, Vol. 36, No. 1, 01.01.2015, p. 22-31.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Selective Allosteric Antagonists for the G Protein-Coupled Receptor GPRC6A Based on the 2-Phenylindole Privileged Structure Scaffold. / Johansson, Henrik; Boesgaard, Michael Worch; Nørskov-Lauritsen, Lenea; Larsen, Inna; Kuhne, Sebastiaan; Gloriam, David E; Bräuner-Osborne, Hans; Sejer Pedersen, Daniel.

    In: Journal of Medicinal Chemistry, Vol. 58, No. 22, 25.11.2015, p. 8938-51.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Identification of the first surrogate agonists for the G protein-coupled receptor GPR132. / Shehata, Mohamed A.; Christensen, Hanna Belcik; Isberg, Vignir; Pedersen, Daniel Sejer; Bender, Andreas; Bräuner-Osborne, Hans; Gloriam, David E.

    In: RSC Advances, Vol. 5, 2015, p. 48551-48557.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. 2014
  10. Published

    Advances in GPCR modeling evaluated by the GPCR Dock 2013 assessment : meeting new challenges. / Kufareva, Irina; Katritch, Vsevolod; Biggin, Phil; Kim, Minsup; Park, Kichul; Jung, Sang Won; Cho, Art E.; Sands, Zara A.; Ostopovici-Halip, Liliana; Bologa, Cristian G.; Norn, Christoffer; Brylinski, Michal; Skolnick, Jeffrey; Keränen, Henrik; Lenselink, Bart E.; Van Westen, Gerard; Overington, John P.; De Teráán, Hugo Gutiérrez; Isberg, Vignir; Fidom, Kimberley M.; Lehto, Thomas M.; Gloriam, David E.; Ghosh, Anirban; Sonavane, Uddhavesh; Joshi, Rajendra; Xia, Jie; Hsieh, Jui Hua; Zhang, Liangren; Wang, Xiang Simon; Vogel, Horst; Yuan, Shuguang; Feng, X.; Chen, M.; Ambia, J.; Barth, P.; Gageat, Cédric; Stepniewski, Michal; Xhaard, Henri; Kelm, Sebastian; Pitt, William R.; Shi, Jiye; Larsen, Adrien; Li, Hubert; Wagner, Jeffrey; Bhattacharya, Supriyo; Vaidehi, Nagarajan; Kanou, Kazuhiko; Cvicek, Vaclav; Kim, Soo Kyung; Trzaskowski, Bartosz; Goddard, William A.; Abrol, Ravinder; Selvam, Balaji; Tikhonova, Irina G.; Cuzzolin, Alberto; Sabbadin, Davide; Ciancetta, Antonella; Moro, Stefano; Freyd, Thibaud; Gabrielsen, Mari; Kristiansen, Kurt; Sylte, Ingebrigt; Gaffney, Kevin J.; Petasis, Nicos A.; Latek, Dorota; Bajda, Marek; Młynarczyk, Krzysztof; Filipek, Sławomir; López, Laura; Kuiper, Michael; Beuming, Thijs; Perez-Aguilar, Jose Manuel; Wang, Ray Yu Ruei; Park, Hahnbeom; Greisen, Per; Song, Yifan; DiMaio, Frank; Baker, David; Shin, Woong Hee; Heo, Lim; Lee, Gyu Rie; Seok, Chaok; Yang, Jianyi; Zhang, Yang; Ponassi, Marco; Rosano, Camillo; Cheremovskiy, Georgy; Grudinin, Sergei; Chaudhari, Rajan; Heim, Andrew J.; Li, Zhijun; Lv, Qiang; Grigorov, Martin G.; Hu, Xin; Sun, Hongmao; Shen, Min; Southall, Noel; Jadhav, Ajit; Rodríguez, David; Ranganathan, Anirudh; Carlsson, Jens; Najmanovich, Rafael; Durdagi, Serdar; De March, Claire; Diharce, Julien; Golebiowski, Jérôme; Antonczak, Serge; Fiorucci, Sébastien; Nguyen, Elizabeth; Meiler, Jens; Gutcaits, Aleksandrs; Marti-Solano, Maria; Pastor, Manuel; Selent, Jana; Stevens, Raymond C.; Abagyan, Ruben.

    In: Structure, Vol. 22, No. 8, 2014, p. 1120-1139.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    mGluR5 : Exploration of Orthosteric and Allosteric Ligand Binding Pockets and Their Applications to Drug Discovery. / Mølck, Christina; Harpsøe, Kasper; Gloriam, David E; Mathiesen, Jesper M; Nielsen, Søren M; Bräuner-Osborne, Hans.

    In: Neurochemical research, Vol. 39, No. 10, 10.2014, p. 1862-1875.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Computer-aided discovery of aromatic L-α-amino acids as agonists of the orphan G protein-coupled receptor GPR139. / Ísberg, Vignir; Andersen, Kirsten Bayer; Bisig, Christoph; Dietz, Gunnar Ph; Bräuner-Osborne, Hans; Gloriam, David Erik.

    In: Journal of chemical information and modeling, Vol. 54, No. 6, 14.05.2014, p. 1553-1557.

    Research output: Contribution to journalJournal articleResearchpeer-review

ID: 5953796