Flemming Steen Jørgensen
Professor
Biostructural Research
Jagtvej 162, 2100 København Ø, 30, Building: 115
- 2016
- Published
Promising Tools in Prostate Cancer Research : Selective Non-Steroidal Cytochrome P450 17A1 Inhibitors. / Bonomo, Silvia; Hansen, Cecilie H; Petrunak, Elyse M; Scott, Emily E; Styrishave, Bjarne; Jørgensen, Flemming Steen; Olsen, Lars.
In: Scientific Reports, Vol. 6, 29468, 12.07.2016.Research output: Contribution to journal › Journal article › Research › peer-review
- 2017
- Published
Dissecting the Cytochrome P450 1A2- and 3A4-Mediated Metabolism of Aflatoxin B1 in Ligand and Protein Contributions. / Bonomo, Silvia; Jørgensen, Flemming Steen; Olsen, Lars.
In: Chemistry: A European Journal, Vol. 23, No. 12, 24.02.2017, p. 2884-2893.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Structure-based optimisation of non-steroidal cytochrome P450 17A1 inhibitors. / Larsen, Morten; Hansen, Cecilie Hurup; Rasmussen, Tobias B.; Styrishave, Bjarne; Olsen, Lars; Jørgensen, Flemming Steen.
In: Chemical Communications, Vol. 53, No. 3118, 3118, 28.02.2017.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The low binding affinity of D-serine at the ionotropic glutamate receptor GluD2 can be attributed to the hinge region. / Tapken, Daniel; Steffensen, Thomas Bielefeldt; Leth, Rasmus; Kristensen, Lise Baadsgaard; Gerbola, Alexander; Gajhede, Michael; Jørgensen, Flemming Steen; Olsen, Lars; Kastrup, Jette Sandholm.
In: Scientific Reports, Vol. 7, 46145, 07.04.2017.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Mechanism of Cytochrome P450 17A1-Catalyzed Hydroxylase and Lyase Reactions. / Bonomo, Silvia; Jørgensen, Flemming Steen; Olsen, Lars.
In: Journal of Chemical Information and Modeling, Vol. 57, No. 5, 22.05.2017, p. 1123-1133.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Aldehyde Oxidase: Reaction Mechanism and Prediction of Site of Metabolism. / Montefiori, Marco; Jorgensen, Flemming Steen; Olsen, Lars.
In: ACS Omega, Vol. 2, No. 8, 08.2017, p. 4237-4244.Research output: Contribution to journal › Journal article › Research › peer-review
- 2018
- Published
The anti-epileptic drug lamotrigine inhibits the CYP17A1 lyase reaction in vitro. / Munkboel, Cecilie Hurup; Christensen, Lise Rudbaek; Islin, Julie; Bonomo, Silvia; Olsen, Lars; Jorgensen, Flemming Steen; Styrishave, Bjarne.
In: Biology of Reproduction, Vol. 99, No. 4, 10.2018, p. 888-897.Research output: Contribution to journal › Journal article › Research › peer-review
- 2019
- Published
Structural analysis of Cytochrome P450 BM3 mutant M11 in complex with dithiothreitol. / Frydenvang, Karla; Verkade-Vreeker, Marlies C A; Dohmen, Floor; Commandeur, Jan N M; Rafiq, Maria; Mirza, Osman; Jørgensen, Flemming Steen; Geerke, Daan P.
In: PLoS ONE, Vol. 14, No. 5, e0217292, 2019.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Fast Methods for Prediction of Aldehyde Oxidase-Mediated Site-of-Metabolism. / Montefiori, Marco; Lyngholm-Kjærby, Casper; Long, Anthony; Olsen, Lars; Jørgensen, Flemming Steen.
In: Computational and Structural Biotechnology Journal, Vol. 17, 01.01.2019, p. 345-351.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Molecular Dynamics Simulations Reveal the Proton:Peptide Coupling Mechanism in the Bacterial Proton-Coupled Oligopeptide Transporter YbgH. / Aduri, Nanda G.; Montefiori, Marco; Khalil, Ruqaiya; Gajhede, Michael; Jørgensen, Flemming Steen; Mirza, Osman.
In: ACS Omega, Vol. 4, No. 1, 31.01.2019, p. 2040-2046.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 1302104
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Forbedret optagelse af lægemidler i organismen: computeren viser vejen
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Synthesis and antiangiogenic activity of N-alkylated levamisole derivatives
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1265
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Design of prodrugs targeting the intestinal di/tri‐peptide transporter hPEPT1 (SLC15A1
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