Flemming Steen Jørgensen
Flemming Steen Jørgensen

Professor


  1. Published

    Forbedret optagelse af lægemidler i organismen: computeren viser vejen

    Larsen, S. B., Jørgensen, Flemming Steen & Olsen, L., 2010, In : Dansk Kemi. 91, 6/7, p. 18-20

    Research output: Contribution to journalJournal articleResearch

  2. Published

    Forudsigelser med hjælp fra det virtuelle rum

    Andersen, R., Steffansen, B., Jørgensen, Flemming Steen & Nielsen, C. U., 2005, In : Lægemiddelforskning. p. 24-25

    Research output: Contribution to journalJournal articleCommunication

  3. Published

    G protein- and agonist-bound serotonin 5-HT2A receptor model activated by steered molecular dynamics simulations

    Ísberg, V., Balle, T., Sander, T., Jørgensen, Flemming Steen & Gloriam, David E., 28 Feb 2011, In : Journal of Chemical Information and Modeling. 51, 2, p. 315-325

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    GABAA receptor agonists, partial agonists, and antagonists. Design and therapeutic prospects

    Krogsgaard-Larsen, Povl, Frølund, Bente, Jørgensen, Flemming Steen & Schousboe, Arne, 1994, In : Journal of Medicinal Chemistry. 37, 16, p. 2489-505 17 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Heterocyclic muscarinic agonists: Structural and therapeutic aspects

    Krogsgaard-Larsen, Povl, Jensen, B., Falch, E. & Jørgensen, Flemming Steen, 1 Jan 1989, In : Drugs of the Future. 14, 6, p. 541-561 21 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Homology building as a means to define antigenic epitopes on dihydrofolate reductase (DHFR) from Plasmodium falciparum

    Alifrangis, Michael, Christensen, I. T., Jørgensen, Flemming Steen, Rønn, A. M., Weng, J. E., Chen, M., Bygbjerg, Ib Christian, Sirawaraporn, W., Palarasah, Y. & Koch, C., 2004, In : Malaria Journal. 3, p. 16

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Homology modelling of the GABA transporter and analysis of tiagabine binding

    Skovstrup, S., Taboureau, O., Bräuner-Osborne, Hans & Jørgensen, Flemming Steen, 2010, In : ChemMedChem. 5, 7, p. 986-1000

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Human peptide transporters: Therapeutic applications

    Nielsen, C. U., Brodin, Birger, Jørgensen, Flemming Steen, Frøkjær, Sven & Steffansen, B., 1 Sep 2002, In : Expert Opinion on Therapeutic Patents. 12, 9, p. 1329-1350 22 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Hvad har varme at gøre med lægemidler?

    Olsen, L., Kasper, C., Kastrup, Jette Sandholm Jensen, Gajhede, Michael & Jørgensen, Flemming Steen, 2006, In : Lægemiddelforskning. p. 31-33

    Research output: Contribution to journalJournal articleCommunication

  10. Published

    Identification of CYP1A2 ligands by structure-based and ligand-based virtual screening

    Poongavanam, V., Lastdrager, J., Oostenbrink, C., Commandeur, J. N. M., Vermeulen, N. P. E., Jørgensen, Flemming Steen & Olsen, L., 2011, In : MedChemComm. 2, 9, p. 853-859

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Identification of a gene on chromosome 12q22 uniquely overexpressed in chronic lymphocytic leukemia

    Buhl, A. M., Jurlander, J., Jørgensen, Flemming Steen, Ottesen, A. M., Cowland, J. B., Gjerdrum, L. M., Hansen, B. V. & Leffers, H., 2006, In : Blood. 107, 7, p. 2904-11 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    In vitro evaluation of N-methyl amide tripeptidomimetics as substrates for the human intestinal di-/tri-peptide transporter hPEPT1

    Andersen, R., Nielsen, C. U., Begtrup, M., Jørgensen, Flemming Steen, Brodin, Birger, Frøkjær, Sven & Steffansen, B., 2006, In : European Journal of Pharmaceutical Sciences. 28, 4, p. 325-35 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Insights into regioselective metabolism of mefenamic acid by cytochrome P450 BM3 mutants through crystallography, docking, molecular dynamics, and free energy calculations

    Capoferri, L., Leth, R., Ter Haar, E., Mohanty, A. K., Grootenhuis, P. D. J., Vottero, E., Commandeur, J. M. N., Vermeulen, N. P. E., Jørgensen, Flemming Steen, Olsen, L. & Geerke, D. P., Mar 2016, In : Proteins: Structure, Function, and Bioinformatics. 84, 3, p. 383-96 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Isolation of a library of aromadendranes from Landolphia dulcis and its characterization using the VolSurf approach

    Stærk, Dan, Skole, B., Jørgensen, Flemming Steen, Budnik, B. A., Ekpe, P. & Jaroszewski, J. W., 2004, In : Journal of Natural Products. 67, 5, p. 799-805 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Mechanism of Cytochrome P450 17A1-Catalyzed Hydroxylase and Lyase Reactions

    Bonomo, S., Jørgensen, Flemming Steen & Olsen, L., 22 May 2017, In : Journal of Chemical Information and Modeling. 57, 5, p. 1123-1133 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    Molecular Dynamics Simulations Reveal the Proton:Peptide Coupling Mechanism in the Bacterial Proton-Coupled Oligopeptide Transporter YbgH

    Aduri, N. G., Montefiori, M., Khalil, R., Gajhede, Michael, Jørgensen, Flemming Steen & Mirza, Osman Asghar, 31 Jan 2019, In : ACS Omega. 4, 1, p. 2040-2046 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Molecular mechanics calculations of proteins. Comparison of different energy minimization strategies

    Christensen, I. T. & Jørgensen, Flemming Steen, 1997, In : Journal of Biomolecular Structure & Dynamics. 15, 3, p. 473-88 16 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Molecular modelling of GABA uptake inhibitors

    Jørgensen, Flemming Steen & Thøgersen, H., 1 Jan 1987, In : Nordic Journal of Psychiatry. 41, 6, p. 483-486 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Mutational mapping and modeling of the binding site for (S)-citalopram in the human serotonin transporter

    Andersen, J., Olsen, L., Hansen, K. B., Taboureau, O., Jørgensen, Flemming Steen, Jørgensen, A. M., Bang-Andersen, B., Egebjerg, J., Strømgaard, Kristian & Kristensen, Anders Skov, 2010, In : Journal of Biological Chemistry. 285, 3, p. 2051-2063

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    New leads of metallo-beta-lactamase inhibitors from structure-based pharmacophore design

    Olsen, L., Jost, S., Adolph, H., Pettersson, I., Hemmingsen, Lars Bo Stegeager & Jørgensen, Flemming Steen, 2006, In : Bioorganic & Medicinal Chemistry. 14, 8, p. 2627-2635 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    On the molecular and electronic features of syn- and anti-sequinorbornene

    Jørgensen, Flemming Steen, 1983, In : Tetrahedron Letters. 24, 47, p. 5289 - 5292

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    On the presence of extremely short H...H non-bonded distances, and orbital interactions through eight s bonds or through two methylene groups in tetramethanonaphthacenes.

    Jørgensen, Flemming Steen & Paddon-Row, M. N., 1983, In : Tetrahedron Letters. 24, 48, p. 5415 - 5418

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Photoelectron spectra of some decahydrotrimethanoanthracenes: Observation of large π orbital interactions through six bonds and an apparent violation of the trans rule

    Jørgensen, Flemming Steen, Paddon-Row, M. N. & Patney, H. K., 1 Jan 1983, In : Journal of the Chemical Society, Chemical Communications. 10, p. 573-575 3 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Polyethers. Structural analysis of the 1,4,5,8-tetraoxadecalins and 2,2'-bis(1,3-dioxolane) by photoelectron spectroscopy, molecular mechanics and molecular orbital calculations

    Jørgensen, Flemming Steen, Nørskov-Lauritsen, L., Jensen, R. B. & Sshroll, G., 1 Jan 1981, In : Tetrahedron. 37, 21, p. 3671-3679 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Prediction methods and databases within chemoinformatics: emphasis on drugs and drug candidates

    Jónsdóttir, S. O., Jørgensen, Flemming Steen & Brunak, Søren, 2005, In : Bioinformatics. 21, 10, p. 2145-60 16 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

ID: 1302104