Flemming Steen Jørgensen

Flemming Steen Jørgensen

Professor


  1. Published

    Prediction of cytochrome P450 mediated metabolism. / Olsen, Lars; Oostenbrink, Chris; Jørgensen, Flemming Steen.

    In: Advanced Drug Delivery Reviews, Vol. 86, 06.05.2015, p. 61-71.

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Published

    Prediction of pH-dependent aqueous solubility of druglike molecules. / Hansen, Niclas Tue; Kouskoumvekaki, Irene; Jørgensen, Flemming Steen; Brunak, Søren; Jónsdóttir, Svava Osk.

    In: Journal of Chemical Information and Modeling, Vol. 46, No. 6, 2012, p. 2601-2609.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Primary structure and conformational analysis of peptide methionine-tyrosine, a peptide related to neuropeptide Y and peptide YY isolated from lamprey intestine. / Conlon, J M; Bjørnholm, B; Jørgensen, Flemming Steen; Youson, J H; Schwartz, T W.

    In: European Journal of Biochemistry, Vol. 199, No. 2, 1991, p. 293-8.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Promising Tools in Prostate Cancer Research : Selective Non-Steroidal Cytochrome P450 17A1 Inhibitors. / Bonomo, Silvia; Hansen, Cecilie H; Petrunak, Elyse M; Scott, Emily E; Styrishave, Bjarne; Jørgensen, Flemming Steen; Olsen, Lars.

    In: Scientific Reports, Vol. 6, 29468, 12.07.2016.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    QSAR models for the human H+/peptide symporter, hPEPT1: Affinity prediction using alignment-independent descriptors. / Larsen, Simon Birksø; Jørgensen, Flemming Steen; Olsen, Lars.

    In: Journal of Chemical Information and Modeling, Vol. 48, No. 1, 2008, p. 233-241.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Relationship between structure, conformational flexibility, and biological activity of agonists and antagonists at the N-methyl-D-aspartic acid subtype of excitatory amino acid receptors. / Madsen, U; Brehm, L; Schaumburg, Kjeld; Jørgensen, Flemming Steen; Krogsgaard-Larsen, P.

    In: Journal of Medicinal Chemistry, Vol. 33, No. 1, 1990, p. 374-80.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Ring inversion of CH2-X-CH2-bridged peri-naphthalenes. A dynamic n.m.r. study. / Anderson, J. Edgar; Jørgensen, Flemming S.; Thomsen, Tove.

    In: Journal of the Chemical Society, Chemical Communications, No. 6, 01.01.1982, p. 333-334.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Risiko for hjerteflimmer afsløres med computermodel. / Taboureau, Olivier; Brunak, Søren; Jørgensen, Flemming Steen.

    In: Lægemiddelforskning, 2008, p. 31-33.

    Research output: Contribution to journalJournal articleCommunication

  9. Published

    SMARTCyp 3.0 : enhanced cytochrome P450 site-of-metabolism prediction server. / Olsen, Lars; Montefiori, Marco; Tran, Khanhvi Phuc; Jørgensen, Flemming Steen.

    In: Bioinformatics (Oxford, England), Vol. 35, No. 17, 01.09.2019, p. 3174-3175.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Salt-bridge Swapping in the EXXERFXYY Motif of Proton Coupled Oligopeptide Transporters. / Aduri, Nanda G; Prabhala, Bala K; Ernst, Heidi A; Jørgensen, Flemming S; Olsen, Lars; Mirza, Osman.

    In: The Journal of Biological Chemistry, Vol. 290, No. 50, 2015, p. 29931-29940.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Search for a trans-Disulfide : Structural Analysis of Di-tert-adamantyl Disulfide by Photoelectron Spectroscopy, Derivation of σI (t-Ad), and Molecular Mechanics Calculations for Related Bulky Disulfides. / Jørgensen, Flemming S.; Snyder, James P.

    In: Journal of Organic Chemistry, Vol. 45, No. 6, 01.01.1980, p. 1015-1020.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Setting the anomeric effect against steric effects in simple acyclic acetals. Non-anomeric non-classical conformations. An n.m.r. and molecular mechanics investigation. / Anderson, J. Edgar; Heki, Katsuhiko; Hirota, Minoru; Jørgensen, Flemming Steen.

    In: Chemical communications (Cambridge, England), Vol. 1987, 1987, p. 554-555.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Small angle X-ray scattering study of calreticulin reveals conformational plasticity. / Toft, Katrine Nørgaard; Larsen, Nanna; Jørgensen, Flemming Steen; Højrup, Peter; Houen, Gunnar; Vestergaard, Bente.

    In: BBA General Subjects, Vol. 1784, No. 9, 2008, p. 1265-1270.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Solvent diversity in polymorph screening. / Allesø, Morten; Van Der Berg, Franciscus Winfried J; Cornett, Claus; Jørgensen, Flemming Steen; Halling-Sørensen, Bent; Lopez de Diego, Heidi; Hovgaard, Lars; Aaltonen, Jaakko; Rantanen, Jukka Tapio.

    In: Journal of Pharmaceutical Sciences, Vol. 97, No. 6, 2008, p. 2145-2159.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Structural analysis of CYP2C9 and CYP2C5 and an evaluation of commonly used molecular modeling techniques. / Afzelius, Lovisa; Raubacher, Florian; Karlén, Anders; Jørgensen, Flemming Steen; Andersson, Tommy B; Masimirembwa, Collen M; Zamora, Ismael.

    In: Drug Metabolism and Disposition, Vol. 32, No. 11, 2004, p. 1218-29.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    Structural analysis of Cytochrome P450 BM3 mutant M11 in complex with dithiothreitol. / Frydenvang, Karla; Verkade-Vreeker, Marlies C A; Dohmen, Floor; Commandeur, Jan N M; Rafiq, Maria; Mirza, Osman; Jørgensen, Flemming Steen; Geerke, Daan P.

    In: PLoS ONE, Vol. 14, No. 5, e0217292, 2019.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Structural and stereochemical requirements for interactions with subtypes of central excitatory amino acid receptors. / Brehm, Lotte; Christensen, Inge T; Nielsen, Birgitte; Reinhardt, Annemarie ; Ebert, Bjarke; Madsen, Ulf; Jørgensen, Flemming Steen; Hansen, Jan J.; Krogsgaard-Larsen, Povl.

    Frontiers in Drug Research; Alfred Benzon Symposium 28. ed. / B. Jensen; F. S. Jørgensen; H. Kofod. Copenhagen : Munksgaard , 1990. p. 92-105.

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  18. Published

    Structural differences of matrix metalloproteinases with potential implications for inhibitor selectivity examined by the GRID/CPCA approach. / Terp, Gitte Elgaard; Cruciani, Gabriele; Christensen, Inge Thøger; Jørgensen, Flemming Steen.

    In: Journal of Medicinal Chemistry, Vol. 45, No. 13, 2002, p. 2675-84.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Structural differences of matrix metalloproteinases. Homology modeling and energy minimization of enzyme-substrate complexes. / Terp, G E; Christensen, I T; Jørgensen, Flemming Steen.

    In: Journal of Biomolecular Structure & Dynamics, Vol. 17, No. 6, 2000, p. 933-46.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Structure-based optimisation of non-steroidal cytochrome P450 17A1 inhibitors. / Larsen, Morten; Hansen, Cecilie Hurup; Rasmussen, Tobias B.; Styrishave, Bjarne; Olsen, Lars; Jørgensen, Flemming Steen.

    In: Chemical Communications, Vol. 53, No. 3118, 3118, 28.02.2017.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    Study on the binding of Thioflavin T to ß-sheet-rich and non-ß-sheet cavities. / Jensen, Minna Grønning; Olsen, Lars; Van De Weert, Marco; Flink, James M.; Frøkjær, Sven; Jørgensen, Flemming Steen.

    In: Journal of Structural Biology, Vol. 158, No. 3, 2007, p. 358-369.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Substrate binding and catalytic mechanism in phospholipase C from Bacillus cereus. a molecular mechanics and molecular dynamics study. / da Graça Thrige, D; Buur, J R; Jørgensen, Flemming Steen.

    In: Biopolymers, Vol. 42, No. 3, 1997, p. 319-36.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Substrate-enzyme interactions and catalytic mechanism in phospholipase C : a molecular modeling study using the GRID program. / Byberg, J R; Jørgensen, Flemming Steen; Hansen, S; Hough, E.

    In: Proteins: Structure, Function, and Bioinformatics, Vol. 12, No. 4, 1992, p. 331-8.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Sulfur-Bridged pen-Naphthalenes : Synthesis, Conformational Analysis, and Photoelectron Spectroscopy of the Mono-, Di-, and Trisulfides of 1,8-Dimethylnaphthalene. / Guttenberger, Hans G.; Bestmann, Hans J.; Dickert, Franz L.; Jorgensen, Flemming S.; Snyder, James P.

    In: Journal of the American Chemical Society, Vol. 103, No. 1, 01.01.1981, p. 159-168.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Synthesis and antiangiogenic activity of N-alkylated levamisole derivatives. / Hansen, Anders N.; Bendiksen, Christine D.; Sylvest, Lene; Friis, Tina; Stærk, Dan; Jørgensen, Flemming Steen; Olsen, Christian Adam; Houen, Gunnar.

    In: P L o S One, Vol. 7, No. 9, 2012.

    Research output: Contribution to journalJournal articleResearchpeer-review

ID: 1302104