Flemming Steen Jørgensen
Professor
Biostructural Research
Jagtvej 162, 2100 København Ø, 30, Building: 115
- Published
In silico predictions of hERG channel blockers in drug discovery : from ligand-based and target-based approaches to systems chemical biology. / Taboureau, Olivier; Jørgensen, Flemming Steen.
In: Combinatorial Chemistry & High Throughput Screening, Vol. 14, No. 5, 06.2011, p. 375-387.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A diversity optimized combinatorial library for the identification of Fc-fragment binding ligands. / Nielsen, Anders L; Jørgensen, Flemming Steen; Olsen, Lars; Christensen, Søren F; Benie, Andrew J; Bjørnholm, Thomas; St. Hilaire, Phaedria M.
In: Biopolymers, Vol. 94, No. 2, 2010, p. 192-205.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A new concept for multidimensional selection of ligand conformations (MultiSelect) and multidimensional scoring (MultiScore) of protein-ligand binding affinities. / Terp, G E; Johansen, B N; Christensen, I T; Jørgensen, Flemming Steen.
In: Journal of Medicinal Chemistry, Vol. 44, No. 14, 2001, p. 2333-43.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A quantitative structure-activity relationship for translocation of tripeptides via the human proton-coupled peptide transporter, hPEPT1 (SLC15A1). / Omkvist, Diana Højmark; Larsen, Simon Birksø; Nielsen, Carsten Uhd; Steffansen, Bente; Olsen, Lars; Jørgensen, Flemming Steen; Larsen, Birger Brodin.
In: The AAPS Journal, Vol. 12, No. 3, 2010, p. 385-396.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A robust force field based method for calculating conformational energies of charged drug-like molecules. / Pøhlsgaard, Jacob; Harpsøe, Kasper; Jørgensen, Flemming Steen; Olsen, Lars.
In: Journal of Chemical Information and Modeling, Vol. 52, No. 2, 2012, p. 409-419.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A steered molecular dynamics study of binding and translocation processes in the GABA transporter. / Skovstrup, Søren; David, Laurent; Taboureau, Olivier; Jørgensen, Flemming Steen.
In: P L o S One, Vol. 7, No. 6, 2012, p. e39360.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Aldehyde Oxidase: Reaction Mechanism and Prediction of Site of Metabolism. / Montefiori, Marco; Jorgensen, Flemming Steen; Olsen, Lars.
In: ACS Omega, Vol. 2, No. 8, 08.2017, p. 4237-4244.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Assessing the relative importance of the biophysical properties of amino acid substitutions associated with human genetic disease. / Terp, Bent N; Cooper, David N; Christensen, Inge T; Jørgensen, Flemming Steen; Bross, Peter Gerd; Gregersen, Niels; Krawczak, Michael.
In: Human Mutation, Vol. 20, No. 2, 2002, p. 98-109.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Biostructure-based drug design. / Jørgensen, Flemming Steen; Kastrup, Jette Sandholm.
Textbook of drug design and discovery. ed. / Povl Krogsgaard-Larsen; Kristian Strømgaard; Ulf Madsen. 4. ed. Boca Raton : CRC Press, 2010. p. 29-42.Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Education
- Published
Classification of cytochrome P450 1A2 inhibitors and noninhibitors by machine learning techniques. / Poongavanam, Vasanthanathan; Taboureau, Olivier; Oostenbrink, Chris; Vermeulen, Nico P E; Olsen, Lars; Jørgensen, Flemming Steen.
In: Drug Metabolism and Disposition, Vol. 37, No. 3, 2009, p. 658-664.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 1302104
Most downloads
-
1705
downloads
Forbedret optagelse af lægemidler i organismen: computeren viser vejen
Research output: Contribution to journal › Journal article › Research
Published -
1599
downloads
Synthesis and antiangiogenic activity of N-alkylated levamisole derivatives
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
1265
downloads
Design of prodrugs targeting the intestinal di/tri‐peptide transporter hPEPT1 (SLC15A1
Research output: Contribution to conference › Conference abstract for conference › Research › peer-review
Published