Flemming Steen Jørgensen

Flemming Steen Jørgensen

Professor


  1. 2017
  2. Published

    Aldehyde Oxidase: Reaction Mechanism and Prediction of Site of Metabolism. / Montefiori, Marco; Jorgensen, Flemming Steen; Olsen, Lars.

    In: ACS Omega, Vol. 2, No. 8, 08.2017, p. 4237-4244.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Mechanism of Cytochrome P450 17A1-Catalyzed Hydroxylase and Lyase Reactions. / Bonomo, Silvia; Jørgensen, Flemming Steen; Olsen, Lars.

    In: Journal of Chemical Information and Modeling, Vol. 57, No. 5, 22.05.2017, p. 1123-1133.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    The low binding affinity of D-serine at the ionotropic glutamate receptor GluD2 can be attributed to the hinge region. / Tapken, Daniel; Steffensen, Thomas Bielefeldt; Leth, Rasmus; Kristensen, Lise Baadsgaard; Gerbola, Alexander; Gajhede, Michael; Jørgensen, Flemming Steen; Olsen, Lars; Kastrup, Jette Sandholm.

    In: Scientific Reports, Vol. 7, 46145, 07.04.2017.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Structure-based optimisation of non-steroidal cytochrome P450 17A1 inhibitors. / Larsen, Morten; Hansen, Cecilie Hurup; Rasmussen, Tobias B.; Styrishave, Bjarne; Olsen, Lars; Jørgensen, Flemming Steen.

    In: Chemical Communications, Vol. 53, No. 3118, 3118, 28.02.2017.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Dissecting the Cytochrome P450 1A2- and 3A4-Mediated Metabolism of Aflatoxin B1 in Ligand and Protein Contributions. / Bonomo, Silvia; Jørgensen, Flemming Steen; Olsen, Lars.

    In: Chemistry: A European Journal, Vol. 23, No. 12, 24.02.2017, p. 2884-2893.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. 2016
  8. Published

    Promising Tools in Prostate Cancer Research : Selective Non-Steroidal Cytochrome P450 17A1 Inhibitors. / Bonomo, Silvia; Hansen, Cecilie H; Petrunak, Elyse M; Scott, Emily E; Styrishave, Bjarne; Jørgensen, Flemming Steen; Olsen, Lars.

    In: Scientific Reports, Vol. 6, 29468, 12.07.2016.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Enantioselective endocrine disrupting effects of omeprazole studied in the H295R cell assay and by molecular modeling. / Sørensen, Amalie Møller; Hansen, Cecilie Hurup; Bonomo, Silvia; Olsen, Lars; Jørgensen, Flemming Steen; Weisser, Johan Juhl; Kretschmann, Andreas Christopher; Styrishave, Bjarne.

    In: Toxicology in Vitro, Vol. 34, 19.03.2016, p. 71-80.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Insights into regioselective metabolism of mefenamic acid by cytochrome P450 BM3 mutants through crystallography, docking, molecular dynamics, and free energy calculations. / Capoferri, Luigi; Leth, Rasmus; Ter Haar, Ernst; Mohanty, Arun K; Grootenhuis, Peter D J; Vottero, Eduardo; Commandeur, Jan M N; Vermeulen, Nico P E; Jørgensen, Flemming Steen; Olsen, Lars; Geerke, Daan P.

    In: Proteins: Structure, Function, and Bioinformatics, Vol. 84, No. 3, 03.2016, p. 383-96.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Cytochrome P450 Mediated Drug Metabolism. / Olsen, Lars; Jørgensen, Flemming Steen; Oostenbrink, Chris.

    New Horizons in Predictive Drug Metabolism and Pharmacokinetics. ed. / Alan G.E. Wilson. Cambridge : Royal Society of Chemistry, 2016. p. 66-78.

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  12. 2015
  13. Published

    Prediction of cytochrome P450 mediated metabolism. / Olsen, Lars; Oostenbrink, Chris; Jørgensen, Flemming Steen.

    In: Advanced Drug Delivery Reviews, Vol. 86, 06.05.2015, p. 61-71.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Density functional theory study on the formation of reactive benzoquinone imines by hydrogen abstraction. / Leth, Rasmus; Rydberg, Patrik; Jørgensen, Flemming Steen; Olsen, Lars.

    In: Journal of Chemical Information and Modeling, Vol. 55, No. 3, 23.03.2015, p. 660-6.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Salt-bridge Swapping in the EXXERFXYY Motif of Proton Coupled Oligopeptide Transporters. / Aduri, Nanda G; Prabhala, Bala K; Ernst, Heidi A; Jørgensen, Flemming S; Olsen, Lars; Mirza, Osman.

    In: The Journal of Biological Chemistry, Vol. 290, No. 50, 2015, p. 29931-29940.

    Research output: Contribution to journalJournal articleResearchpeer-review

ID: 1302104