Employees – University of Copenhagen

Hans Bräuner-Osborne

Hans Bräuner-Osborne

Professor


  1. 2019
  2. Published

    Identification of a novel scaffold for a small molecule GPR139 receptor agonist. / Jensen, Anne Cathrine Nøhr; Shehata, Mohamed A.; Palmer, Daniel; Pokhrel, Rina; Vallianou, Maria; Foster, Simon Richard; Gentry, Patrick Ryan; Gloriam, David E.; Bräuner-Osborne, Hans.

    In: Scientific Reports, 07.03.2019.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. E-pub ahead of print

    Rational design of a heterotrimeric G protein α subunit with artificial inhibitor sensitivity. / Malfacini, Davide; Patt, Julian; Annala, Suvi; Harpsøe, Kasper; Eryilmaz, Funda; Reher, Raphael; Crüsemann, Max; Hanke, Wiebke; Zhang, Hang; Tietze, Daniel; Gloriam, David E; Bräuner-Osborne, Hans; Strømgaard, Kristian; König, Gabriele M; Inoue, Asuka; Gomeza, Jesus; Kostenis, Evi.

    In: The Journal of Biological Chemistry, 11.02.2019.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Identification of a novel scaffold for a small molecule GPR139 receptor agonist. / Nøhr, Anne Cathrine; Shehata, Mohamed A; Palmer, Daniel; Pokhrel, Rina; Vallianou, Maria; Foster, Simon R; Gentry, Patrick R; Gloriam, David E; Bräuner-Osborne, Hans.

    In: Scientific Reports, Vol. 9, No. 1, 07.03.2019, p. 3802.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. 2018
  6. Published

    Human GIP(3-30)NH inhibits G protein-dependent as well as G protein-independent signaling and is selective for the GIP receptor with high-affinity binding to primate but not rodent GIP receptors. / Gabe, Maria Buur Nordskov; Sparre-Ulrich, Alexander Hovard; Pedersen, Mie Fabricius; Gasbjerg, Lærke Smidt; Inoue, Asuka; Bräuner-Osborne, Hans; Hartmann, Bolette; Rosenkilde, Mette Marie.

    In: Biochemical Pharmacology, Vol. 150, 31.01.2018, p. 97-107.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Structure–activity relationship and conformational studies of the natural product cyclic depsipeptides YM-254890 and FR900359. / Zhang, Hang; Nielsen, Alexander L.; Boesgaard, Michael W.; Harpsøe, Kasper; Daly, Norelle L.; Xiong, Xiao-feng; Underwood, Christina R.; Haugaard-kedström, Linda M.; Bräuner-osborne, Hans; Gloriam, David E.; Strømgaard, Kristian.

    In: European Journal of Medicinal Chemistry, Vol. 156, 05.08.2018, p. 847-860.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. 2017
  9. Published

    Applying label-free dynamic mass redistribution assay for studying endogenous FPR1 receptor signalling in human neutrophils. / Christensen, Hanna B; Gloriam, David E; Pedersen, Daniel Sejer; Cowland, Jack B; Borregaard, Niels; Bräuner-Osborne, Hans.

    In: Journal of Pharmacological and Toxicological Methods, Vol. 88, No. Pt 1, 15.07.2017, p. 72-78.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Robust GLP-1 secretion by basic L-amino acids does not require the GPRC6A receptor. / Clemmensen, Christoffer; Jørgensen, Christinna V; Smajilovic, Sanela; Bräuner-Osborne, Hans.

    In: Diabetes, Obesity and Metabolism, Vol. 19, No. 4, 2017, p. 599-603.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Investigating Internalization and Intracellular Trafficking of GPCRs : New Techniques and Real-Time Experimental Approaches. / Foster, Simon R; Bräuner-Osborne, Hans.

    Handbook of Experimental Pharmacology. Vol. 245 Springer, 2017. p. 41-61.

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  12. Published

    Identification of Histamine H3 Receptor Ligands Using a New Crystal Structure Fragment-based Method. / Frandsen, Ida Osborn; Boesgaard, Michael W; Fidom, Kimberley; Hauser, Alexander S; Isberg, Vignir; Bräuner-Osborne, Hans; Wellendorph, Petrine; Gloriam, David E.

    In: Scientific Reports, Vol. 7, No. 1, 4829, 06.07.2017.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Structural insight to mutation effects uncover a common allosteric site in class C GPCRs. / Harpsøe, Kasper; Boesgaard, Michael W; Munk, Christian; Bräuner-Osborne, Hans; Gloriam, David E.

    In: Bioinformatics (Oxford, England), Vol. 33, No. 8, btw784, 2017, p. 1116-1120.

    Research output: Contribution to journalJournal articleResearchpeer-review

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