Henrik Franzyk

Henrik Franzyk

Associate Professor


  1. 2019
  2. E-pub ahead of print

    Mechanistic profiling of the release kinetics of siRNA from lipidoid-polymer hybrid nanoparticles in vitro and in vivo after pulmonary administration. / Thanki, Kaushik; van Eetvelde, Delphine; Geyer, Antonia; Fraire, Juan; Hendrix, Remi; Van Eygen, Hannelore; Putteman, Emma; Sami, Haider; de Souza Carvalho-Wodarz, Cristiane; Franzyk, Henrik; Nielsen, Hanne Mørck; Braeckmans, Kevin; Lehr, Claus-Michael; Ogris, Manfred; Foged, Camilla.

    In: Journal of controlled release : official journal of the Controlled Release Society, 06.08.2019.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Identification of Factors of Importance for Spray Drying of Small Interfering RNA-Loaded Lipidoid-Polymer Hybrid Nanoparticles for Inhalation. / Dormenval, Cypriane; Lokras, Abhijeet; Cano-Garcia, Guillermo; Wadhwa, Abishek; Thanki, Kaushik; Rose, Fabrice; Thakur, Aneesh; Franzyk, Henrik; Foged, Camilla.

    In: Pharmaceutical Research, Vol. 36, No. 10, 02.08.2019, p. 142.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Philanthotoxin Analogues That Selectively Inhibit Ganglionic Nicotinic Acetylcholine Receptors with Exceptional Potency. / Kachel, Hamid S.; Franzyk, Henrik; Mellor, Ian R.

    In: Journal of Medicinal Chemistry, Vol. 62, No. 13, 11.07.2019, p. 6214-6222.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Repurposing Azithromycin and Rifampicin Against Gram-Negative Pathogens by Combination With Peptidomimetics. / Baker, Kristin R.; Jana, Bimal; Hansen, Anna Mette; Nielsen, Hanne Morck; Franzyk, Henrik; Guardabassi, Luca.

    In: Frontiers in Cellular and Infection Microbiology, Vol. 9, 02.07.2019.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. E-pub ahead of print

    Lipidoid-Polymer Hybrid Nanoparticles Loaded with TNF siRNA Suppress Inflammation after Intra-articular Administration in a Murine Experimental Arthritis Model. / Jansen, Manon A A; Klausen, Lasse H; Thanki, Kaushik; Lyngsø, Jeppe; Skov Pedersen, Jan; Franzyk, Henrik; Nielsen, Hanne M; van Eden, Willem; Dong, Mingdong; Broere, Femke; Foged, Camilla; Zeng, Xianghui.

    In: European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 11.06.2019.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Macrophage phosphoproteome analysis reveals MINCLE-dependent and -independent mycobacterial cord factor signaling. / Hansen, Madlen; Peltier, Julien; Killy, Barbara; Amin, Bushra; Bodendorfer, Barbara; Härtlova, Anetta; Uebel, Sebastian; Bosmann, Markus; Hofmann, Jörg; Büttner, Christian; Ekici, Arif B; Kuttke, Mario; Franzyk, Henrik; Foged, Camilla; Beer-Hammer, Sandra; Schabbauer, Gernot; Trost, Matthias; Lang, Roland.

    In: Molecular and Cellular Proteomics, Vol. 18, No. 4, 04.2019, p. 669-685.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Structure-Function Characteristics and Signaling Properties of Lipidated Peptidomimetic FPR2 Agonists : Peptoid Stereochemistry and Residues in the Vicinity of the Headgroup Affect Function. / Holdfeldt, Andre; Skovbakke, Sarah Line; Gabl, Michael; Nielsen, Christina; Dahlgren, Claes; Franzyk, Henrik; Forsman, Huamei.

    In: ACS Omega, Vol. 4, No. 3, 28.03.2019, p. 5968-5982.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Application of a Quality-By-Design Approach to Optimise Lipid-Polymer Hybrid Nanoparticles Loaded with a Splice-Correction Antisense Oligonucleotide : Maximising Loading and Intracellular Delivery. / Thanki, Kaushik; Papai, Simon; Lokras, Abhijeet; Rose, Fabrice; Falkenberg, Emily; Franzyk, Henrik; Foged, Camilla.

    In: Pharmaceutical Research, Vol. 36, No. 3, 09.01.2019, p. 37.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    19F-substituted amino acids as an alternative to fluorophore labels: monitoring of degradation and cellular uptake of analogues of penetratin by 19F NMR. / Christensen, Malene Vinther; Kongstad, Kenneth Thermann; Sondergaard, Teis Esben; Stærk, Dan; Nielsen, Hanne Mørck; Franzyk, Henrik; Wimmer, Reinhard.

    In: Journal of Biomolecular N M R, Vol. 73, 2019, p. 167-182.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Antimicrobial Activity of α-Peptide/β-Peptoid Lysine-Based Peptidomimetics Against Colistin-Resistant Pseudomonas aeruginosa Isolated From Cystic Fibrosis Patients. / Molchanova, Natalia; Wang, Hengzhuang; Hansen, Paul R; Høiby, Niels; Nielsen, Hanne M; Franzyk, Henrik.

    In: Frontiers in Microbiology, Vol. 10, 275, 2019.

    Research output: Contribution to journalJournal articleResearchpeer-review

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