Jesper Langgaard Kristensen

Jesper Langgaard Kristensen

Professor with special responsibilities


  1. Published

    (11)C-labeling and preliminary evaluation of pimavanserin as a 5-HT2A receptor PET-radioligand. / Andersen, Valdemar L; Hansen, Hanne D; Herth, Matthias M; Dyssegaard, Agnete; Knudsen, Gitte M; Kristensen, Jesper Langgaard.

    In: Bioorganic & Medicinal Chemistry Letters, Vol. 25, No. 5, 20.01.2015, p. 1053–1056.

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Published

    (11)C-labeling and preliminary evaluation of vortioxetine as a PET radioligand. / Andersen, Valdemar L; Hansen, Hanne D; Herth, Matthias M; Knudsen, Gitte M; Kristensen, Jesper Langgaard.

    In: Bioorganic & Medicinal Chemistry Letters, Vol. 24, No. 11, 19.04.2014, p. 2408-2411.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    18F-Labelling of electron rich iodonium ylides : application to the radiosynthesis of potential 5-HT2A receptor PET ligands. / Petersen, I N; Villadsen, J; Hansen, H D; Madsen, J; Jensen, A A; Gillings, N; Lehel, Szabolcs; Herth, M M; Knudsen, G M; Kristensen, J L.

    In: Organic & Biomolecular Chemistry, Vol. 15, 04.2017, p. 4351-4358.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    5-HT2A/5-HT2C receptor pharmacology and intrinsic clearance of N-benzylphenethylamines modified at the primary site of metabolism. / Leth-Petersen, Sebastian; Petersen, Ida Nymann; Jensen, Anders A; Bundgaard, Christoffer; Bæk, Mathias; Kehler, Jan; Kristensen, Jesper L.

    In: A C S Chemical Neuroscience, 26.08.2016, p. 1-6.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    A Prodrug Approach Involving In Situ Depot Formation to Achieve Localized and Sustained Action of Diclofenac After Joint Injection. / Thing, Mette; Agårdh, Li; Larsen, Susan; Rasmussen, Rune; Pallesen, Jakob; Mertz, Nina; Kristensen, Jesper Langgaard; Hansen, Martin; Ostergaard, Jesper; Larsen, Claus Selch.

    In: Journal of Pharmaceutical Sciences, Vol. 103, No. 12, 2014, p. 4021–4029.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    A strategic approach to [6,6]-bicyclic lactones : application towards the CD fragment of DHβE. / Jepsen, Tue Heesgaard; Glibstrup, Emil; Crestey, Francois Louis Jean; Jensen, Anders A.; Kristensen, Jesper Langgaard.

    In: Beilstein Journal of Organic Chemistry, Vol. 13, 2017, p. 988-994.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Accelerating preclinical PET-screening: reductive amination with [11C]methoxybenzaldehydes. / Herth, Matthias Manfred; Leth-Petersen, Sebastian; Lehel, Szabolcs; Hansen, Martin; Gillings, Nic; Madsen, Jacob; Kristensen, Jesper Langgaard.

    In: R S C Advances, Vol. 41, 2014, p. 21347-21350.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Amination of aryl iodides using a fluorous-tagged ammonia equivalent. / Nielsen, Simon Dalsgaard; Smith, Garrick; Begtrup, Mikael; Kristensen, Jesper Langgaard.

    In: European Journal of Organic Chemistry, Vol. 2010, No. 19, 2010, p. 3704-3710.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Aminolysis of resin-bound N-nosylaziridine-2-carboxylic acids. / Olsen, Christian A; Christensen, Caspar; Nielsen, Birgitte; Farah, Mohamed M; Mohamed, Farah M; Witt, Matthias; Clausen, Rasmus P; Kristensen, Jesper L; Franzyk, Henrik; Jaroszewski, Jerzy W.

    In: Organic Letters, Vol. 8, No. 15, 2006, p. 3371-4.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    An Improved Radiolabelling Strategy for the 5-HT2A Agonist, [C-11]Cimbi-36. / Gillings, Nic; Lehel, Szabolcs; Herth, Matthias; Leth-Petersen, Sebastian; Madsen, Jacob; Gabel-Jensen, Charlotte; Kristensen, Jesper L.

    In: Journal of Labelled Compounds and Radiopharmaceuticals, Vol. 58, 15.05.2015, p. S296-S296.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  11. Published

    Characterization of the hepatic cytochrome P450 enzymes involved in the metabolism of 25I-NBOMe and 25I-NBOH. / Nielsen, Line Marie; Holm, Niels Bjerre; Leth-Petersen, Sebastian; Kristensen, Jesper Langgaard; Olsen, Lars; Linnet, Kristian.

    In: Drug Testing and Analysis, Vol. 9, No. 5, 2017, p. 671–679.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Computational Methods to Predict the Regioselectivity of Electrophilic Aromatic Substitution Reactions of Heteroaromatic Systems. / Kruszyk, Monika; Jessing, Mikkel; Kristensen, Jesper L; Jorgensen, Morten.

    In: Journal of Organic Chemistry, Vol. 81, No. 12, 13.05.2016, p. 5128–5134.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Concise synthesis of new bridged-nicotine analogues. / Crestey, François; Hooyberghs, Geert ; Kristensen, Jesper Langgaard.

    In: Tetrahedron, Vol. 68, No. 5, 04.02.2012, p. 1417-1421.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Conformationally Constrained Peptidomimetics as Inhibitors of the Protein Arginine Methyl Transferases. / Knuhtsen, Astrid; Legrand, Baptiste; Van der Poorten, Olivier; Amblard, Muriel; Martinez, Jean; Ballet, Steven; Kristensen, Jesper L; Pedersen, Daniel Sejer.

    In: Chemistry: A European Journal, Vol. 22, No. 39, 12.08.2016, p. 14022–14028.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Accepted/In press

    Convenient Entry to 18 F-Labeled Amines through the Staudinger Reduction. / Stéen, E. Johanna L.; Shalgunov, Vladimir; Denk, Christoph; Mikula, Hannes; Kjær, Andreas; Kristensen, Jesper L.; Herth, Matthias M.

    In: European Journal of Organic Chemistry, 01.01.2019.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    Convenient access to F-18-labeled amines through the Staudinger reduction. / Shalgunov, Vladimir; Steen, Johanna; Denk, Christoph; Mikula, Hannes; Kjaer, Andreas; Kristensen, Jesper; Herth, Matthias.

    In: Journal of Labelled Compounds and Radiopharmaceuticals, Vol. 62, No. Supl. 1/SI, P-050, 05.2019, p. S205-S206.

    Research output: Contribution to journalConference abstract in journalResearch

  17. Published

    Convergent [18]F-labeling and evaluation of N-benzyl-phenethylamines as 5-HT2A receptor PET ligands. / Petersen, Ida Nymann; Villadsen, Jonas; Hansen, Hanne Demant; Jensen, Anders A; Lehel, Szabolcs; Gillings, Nic; Herth, Matthias M; Knudsen, Gitte M; Kristensen, Jesper L.

    In: Bioorganic & Medicinal Chemistry, Vol. 24, 2016, p. 5353-5356.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Convergent synthesis of 3-arylated 1-hydroxypyrazoles via 3-metalated pyrazole-1-oxides. / Eskildsen, Jørgen; Kristensen, Jesper Langgaard; Vedsø, P.; Begtrup, M.; Kristensen, Jesper Langgaard.

    In: Journal of Organic Chemistry, Vol. 66, No. 25, 14.12.2001, p. 8654-8656.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Convergent synthesis of 6-substituted phenanthridines via anionic ring closure. / Lysén, M.; Kristensen, Jesper Langgaard; Vedsø, P.; Begtrup, M.

    In: Organic Letters, Vol. 4, No. 2, 01.01.2002, p. 257-259.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Correction : Structure-activity relationships of constrained phenylethylamine ligands for the serotonin 5-HT2 receptors (PLoS ONE). / Isberg, Vignir; Paine, James; Leth-Petersen, Sebastian; Kristensen, Jesper L.; Gloriam, David E.

    In: PLOS ONE, Vol. 9, No. 1, 17.01.2014.

    Research output: Contribution to journalComment/debateResearchpeer-review

  21. Published

    Correlating the Metabolic Stability of Psychedelic 5-HT2A Agonists with Anecdotal Reports of Human Oral Bioavailability. / Leth-Petersen, Sebastian; Bundgaard, Christoffer; Hansen, Martin; Carnerup, Martin A; Kehler, Jan; Kristensen, Jesper Langgaard.

    In: Neurochemical Research, Vol. 39, No. 10, 12.02.2014, p. 2018-2023.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Crystal Structure of Lymnaea stagnalis AChBP Complexed with the Potent nAChR Antagonist DHßE Suggests a Unique Mode of Antagonism. / Shahsavar, Azadeh; Kastrup, Jette S; Nielsen, Elsebet Ø.; Kristensen, Jesper L; Gajhede, Michael; Balle, Thomas.

    In: P L o S One, Vol. 7, No. 8, 2012, p. e40757.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Deprotection of 2-nitrobenzenesulfonamides using fluorous and solid phase reagents. / Christensen, C; Clausen, Rasmus Prætorius; Begtrup, M; Kristensen, Jesper Langgaard.

    In: Tetrahedron Letters, Vol. 45, No. 43, 18.10.2004, p. 7991-7993.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Design, synthesis and biological evaluation of Erythrina alkaloid analogues as neuronal nicotinic acetylcholine receptor antagonists. / Crestey, François; Jensen, Anders A.; Borch, Morten; Andreasen T., Jesper; Andersen, Jacob; Balle, Thomas; Kristensen, Jesper Langgaard.

    In: Journal of Medicinal Chemistry, Vol. 56, No. 23, 2013, p. 9673-9682.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published
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