Jesper Langgaard Kristensen
Jesper Langgaard Kristensen

Professor with special responsibilities


  1. 2020
  2. E-pub ahead of print

    Diclofenac prodrugs for intra-articular depot injectables: In vitro hydrolysis and species variation

    Storgaard, I. H., Kristensen, Jesper Langgaard, Larsen, C., Mertz, Nina, Østergaard, Jesper & Larsen, Susan Weng, 9 Jan 2020, In : Journal of Pharmaceutical Sciences.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. 2019
  4. E-pub ahead of print

    Trans-Cyclooctene-Functionalized PeptoBrushes with Improved Reaction Kinetics of the Tetrazine Ligation for Pretargeted Nuclear Imaging

    Stéen, E. J. L., Jørgensen, Jesper Tranekjær, Johann, K., Norregaard, K., Sohr, B., Svatunek, D., Birke, A., Shalgunov, Vladimir, Edem, P. E., Rossin, R., Seidl, C., Schmid, F., Robillard, M. S., Kristensen, Jesper Langgaard, Mikula, H., Barz, M., Kjær, Andreas & Herth, Matthias Manfred, 10 Dec 2019, In : ACS NANO.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. E-pub ahead of print

    Locomotor effects of 3,4-methylenedioxymethamphetamine (MDMA) and its deuterated form in mice: psychostimulant effects, stereotypy, and sensitization

    Berquist, M. D., Leth-Petersen, S., Kristensen, Jesper Langgaard & Fantegrossi, W. E., 15 Nov 2019, In : Psychopharmacology.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. E-pub ahead of print

    The 5-hydroxytryptamine 2A receptor agonists DOI and 25CN-NBOH decrease marble burying and reverse 8-OH-DPAT-induced deficit in spontaneous alternation

    Odland, Anna Ulstein, Jessen, L., Kristensen, Jesper Langgaard, Fitzpatrick, C. M. & Andreasen T., Jesper, 3 Nov 2019, In : Neuropharmacology. p. 107838

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Radiolabeling and in vivo evaluation of [11C]AGH-44: a potential lead structure to develop a positron emission tomography radioligand for the 5-HT7 receptor

    L’Estrade, E. T., Petersen, I. N., Xiong, M., Hogendorf, A. S., Hogendorf, A., Kristensen, Jesper Langgaard, Kjær, Andreas, Bojarski, A. J., Erlandsson, M., Ohlsson, T., Knudsen, Gitte Moos & Herth, Matthias Manfred, 1 Nov 2019, In : Journal of Radioanalytical and Nuclear Chemistry. 322, 2, p. 847-851 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. E-pub ahead of print

    Dark Classics in Chemical Neuroscience: NBOMes

    Poulie, Christian Bernard Matthijs, Jensen, Anders A., Halberstadt, A. & Kristensen, Jesper Langgaard, 28 Oct 2019, In : ACS Chemical Neuroscience.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Convenient access to F-18-labeled amines through the Staudinger reduction

    Shalgunov, Vladimir, Steen, J., Denk, C., Mikula, H., Kjær, Andreas, Kristensen, Jesper Langgaard & Herth, Matthias Manfred, May 2019, In : Journal of Labelled Compounds and Radiopharmaceuticals. 62, Supl. 1/SI, p. S205-S206 P-050.

    Research output: Contribution to journalConference abstract in journalResearch

  10. Published

    Enantioselective Total Synthesis of (+)-Dihydro-β-erythroidine

    Clementson, S., Jessing, M., Pedersen, H., Vital, P. & Kristensen, Jesper Langgaard, May 2019, In : Journal of the American Chemical Society. 141, 22, p. 8783-8786

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Pretargeted PET imaging using a dual click F-18-labeling strategy: [Meeting Abstract]

    Steen, J., Denk, C., Jørgensen, Jesper Tranekjær, Norregard, K., Rossin, R., Wilkovitsch, M., Svatunek, D., Edem, P., Kuntner, C., Wanek, T., Robillard, M., Kristensen, Jesper Langgaard, Kjær, Andreas, Mikula, H. & Herth, Matthias Manfred, May 2019, In : Journal of Labelled Compounds and Radiopharmaceuticals. 62, Supl. 1/SI, p. S22-S23 O-08.

    Research output: Contribution to journalConference abstract in journalResearch

  12. Published

    Trans-cyclooctene-functionalized PeptoBrushes with improved reaction kinetics of the tetrazine ligation for pretargeted nuclear imaging: [Meeting Abstract]

    Steen, J., Norregard, K., Johann, K., Jørgensen, Jesper Tranekjær, Svatunek, D., Birke, A., Edem, P., Rossin, R., Seidl, C., Schmid, F., Robillard, M., Mikula, H., Kristensen, Jesper Langgaard, Barz, M., Kjær, Andreas & Herth, Matthias Manfred, May 2019, In : Journal of Labelled Compounds and Radiopharmaceuticals. 62, Supl. 1/SI, p. S109-S110

    Research output: Contribution to journalConference abstract in journalResearch

  13. Accepted/In press

    Convenient Entry to 18 F-Labeled Amines through the Staudinger Reduction

    Stéen, E. J. L., Shalgunov, Vladimir, Denk, C., Mikula, H., Kjær, Andreas, Kristensen, Jesper Langgaard & Herth, Matthias Manfred, 1 Jan 2019, (Accepted/In press) In : European Journal of Organic Chemistry.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Improved radiosynthesis and preliminary in vivo evaluation of the 11 C-labeled tetrazine [ 11 C]AE-1 for pretargeted PET imaging

    Stéen, E. J. L., Jørgensen, Jesper Tranekjær, Petersen, I. N., Nørregaard, K., Lehel, S., Shalgunov, Vladimir, Birke, A., Edem, P. E., L'Estrade, E. T., Hansen, H. D., Villadsen, J., Erlandsson, M., Ohlsson, T., Yazdani, A., Valliant, J. F., Kristensen, Jesper Langgaard, Barz, M., Knudsen, Gitte Moos, Kjær, Andreas & Herth, Matthias Manfred, 1 Jan 2019, In : Bioorganic and Medicinal Chemistry Letters. 29, 8, p. 986-990

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Human biodistribution and radiation dosimetry of the 5-HT2A receptor agonist Cimbi-36 labeled with carbon-11 in two positions

    Johansen, A., Holm, Søren, Dall, B., Keller, S., Kristensen, Jesper Langgaard, Knudsen, Gitte Moos & Hansen, H. D., 2019, In : EJNMMI Research. 9, p. 1-10 10 p., 71.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. 2018
  17. Published

    Towards the Dual Click F-18-labeling of Antibodies

    Steen, J., Denk, C., Norregaard, K., Jorgensen, J., Rossin, R., Svatunek, D., Edem, P., Robillard, M., Kjær, Andreas, Kristensen, Jesper Langgaard, Mikula, H. & Herth, Matthias Manfred, 1 May 2018.

    Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

  18. Published

    The importance of small polar radiometabolites in molecular neuroimaging: A PET study with [11C]Cimbi-36 labeled in two positions

    Johansen, A., Hansen, H. D., Svarer, C., Lehel, S., Leth-Petersen, S., Kristensen, Jesper Langgaard, Gillings, N. & Knudsen, Gitte Moos, Apr 2018, In : Journal of Cerebral Blood Flow and Metabolism. 38, 4, p. 659-668

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Dual Nicotinic Acetylcholine Receptor α4β2 Antagonists/α7 Agonists: Synthesis, Docking Studies, and Pharmacological Evaluation of Tetrahydroisoquinolines and Tetrahydroisoquinolinium Salts

    Crestey, F., Jensen, Anders A., Soerensen, C., Magnus, C. B., Andreasen T., Jesper, Peters, G. H. J. & Kristensen, Jesper Langgaard, 2018, In : Journal of Medicinal Chemistry. 61, p. 1719-1729

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. 2017
  21. Published

    Synthesis, radiofluorination, and preliminary evaluation of the potential 5-HT2A receptor agonists [18 F]Cimbi-92 and [18 F]Cimbi-150

    Edgar, F. G., Hansen, H. D., Leth-Petersen, S., Ettrup, A., Kristensen, Jesper Langgaard, Knudsen, Gitte Moos & Herth, Matthias Manfred, Oct 2017, In : Journal of Labelled Compounds and Radiopharmaceuticals. 60, 12, p. 586-591 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    18F-Labelling of electron rich iodonium ylides: application to the radiosynthesis of potential 5-HT2A receptor PET ligands

    Petersen, I. N., Villadsen, J., Hansen, H. D., Madsen, J., Jensen, Anders A., Gillings, N., Lehel, S., Herth, Matthias Manfred, Knudsen, Gitte Moos & Kristensen, Jesper Langgaard, Apr 2017, In : Organic & Biomolecular Chemistry. 15, p. 4351-4358

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Ortho lithiation-in situ borylation of substituted morpholine benzamides

    Cederbalk, A., Lysén, M., Kehler, J. & Kristensen, Jesper Langgaard, 23 Mar 2017, In : Tetrahedron. 73, 12, p. 1576–1582 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Nucleophilic 18F-Labeling of Spirocyclic Iodonium Ylide or Boronic Pinacol Ester Precursors - Advantages and Disadvantages

    Petersen, I. N., Kristensen, Jesper Langgaard & Herth, Matthias Manfred, 18 Jan 2017, In : European Journal of Organic Chemistry. 2017, 3, p. 453-458 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Development of a simple proton nuclear magnetic resonance-based procedure to estimate the approximate distribution coefficient at physiological pH (logD7.4): Evaluation and comparison to existing practices

    Stéen, E. J. L., Nyberg, N., Lehel, S., Andersen, V. L., Di Pilato, P., Knudsen, Gitte Moos, Kristensen, Jesper Langgaard & Herth, Matthias Manfred, 15 Jan 2017, In : Bioorganic & Medicinal Chemistry Letters. 27, 2, p. 319-322 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    A strategic approach to [6,6]-bicyclic lactones: application towards the CD fragment of DHβE

    Jepsen, T. H., Glibstrup, E., Crestey, F. L. J., Jensen, Anders A. & Kristensen, Jesper Langgaard, 2017, In : Beilstein Journal of Organic Chemistry. 13, p. 988-994 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Published

    Characterization of the hepatic cytochrome P450 enzymes involved in the metabolism of 25I-NBOMe and 25I-NBOH

    Nielsen, L. M., Holm, N. B., Leth-Petersen, S., Kristensen, Jesper Langgaard, Olsen, L. & Linnet, Kristian, 2017, In : Drug Testing and Analysis. 9, 5, p. 671–679

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. Published

    Detailed characterization of the in vitro pharmacological and pharmacokinetic properties of N-(2-hydroxybenzyl)-2,5-dimethoxy-4-cyanophenylethylamine (25CN-NBOH), a highly selective and brain-penetrant 5-HT2A receptor agonist

    Jensen, Anders A., McCorvy, J. D., Petersen, S. L., Bundgaard, C., Liebscher, G., Kenakin, T. P., Bräuner-Osborne, Hans, Kehler, J. & Kristensen, Jesper Langgaard, 2017, In : Journal of Pharmacology and Experimental Therapeutics. 361, 3, p. 441-453

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. Published

    Textbook of Drug Design and Discovery: In vivo imaging in drug discovery

    Kristensen, Jesper Langgaard & Herth, Matthias Manfred, 2017, Textbook of Drug Design and Discovery. Fifth edition ed. CRC Press

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearch

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