Jette Sandholm Jensen Kastrup
Jette Sandholm Jensen Kastrup

Professor

  • Peptides and Proteins

    Jagtvej 162

    2100 København Ø

    Phone: +45 35 33 64 86

Introductory remarks on publicationslist


Publications 1988-2013 by Jette Sandholm Kastrup

Peer-reviewed: 93

    1990-1994: 4
    1995-1999: 12
    2000-2004: 17
    2005-2009: 37
    2010-May 2013: 23

Books (editor, chapters): 7
Patents: 2
Other publications: 28
PhD thesis: 1
Structures deposited in the Protein Data Bank: 106


  1. 2007
  2. Published

    Partial agonism and antagonism of the ionotropic glutamate receptor iGLuR5: Structures of the ligand-bining core in complex with domoic acid and 2-amino-3-[5-tert-butyl-3-(phosphonomethoxy)-4-isoxazolyl]propionic acid

    Hald, H., Naur, P., Pickering, Darryl S, Sprogøe, D., Madsen, Ulf, Timmermann, D. B., Ahring, P. K., Liljefors, T., Schousboe, Arne, Egebjerg, J., Gajhede, Michael & Kastrup, Jette Sandholm Jensen, 2007, In : Journal of Biological Chemistry. 282, 35, p. 25726-25736

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Gennembrud i forståelsen af insulinfibrillering

    Jensen, M. G., Vestergaard, Bente, Frøkjær, Sven, Gajhede, Michael, Flink, J. M., van de Weert, Marco, Kastrup, Jette Sandholm Jensen & Svergun, D. I., 2007, In : Lægemiddelforskning. p. 10-11

    Research output: Contribution to journalJournal articleCommunication

  4. Published

    Design and characterization of dimeric ligands cross-linking two identical modulatory AMPA receptor sites

    Kaae, B. H., Harpsøe, Kasper, Sanz, A. C., Pickering, Darryl S, Sauerberg, P., Clausen, Rasmus Prætorius, Kastrup, Jette Sandholm Jensen, Liljefors, T. & Madsen, Ulf, 19 Aug 2007, In : American Chemical Society. Abstracts of Papers (at the National Meeting). 234

    Research output: Contribution to journalConference abstract in journalResearch

  5. Published

    Structural proof of a dimeric positive modulator bridging two identical AMPA receptor-binding sites

    Kaae, B. H., Harpsøe, Kasper, Kastrup, Jette Sandholm Jensen, Sanz, A. C., Pickering, Darryl S, Metzler, B., Clausen, Rasmus Prætorius, Gajhede, Michael, Sauerberg, P., Liljefors, T. & Madsen, Ulf, 2007, In : Chemistry & Biology. 14, 11, p. 1294-303 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Structure of rat acidic fibroblast growth factor at 1.4 A resolution.

    Kulahin, N., Kiselyov, V., Kochoyan, A., Kristensen, O., Kastrup, Jette Sandholm Jensen, Berezin, V., Bock, E. M. & Gajhede, Michael, 2007, In : Acta Crystallographica. Section F : Structural Biology and Crystallization Communications. 63, Pt2, p. 65-68 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Ionotropic glutamate-like receptor d2 binds D-serine and glycine.

    Naur, P., Hansen, K. B., Kristensen, Anders Skov, Dravid, S. M., Pickering, Darryl S, Olsen, L., Vestergaard, Bente, Egebjerg, J., Gajhede, Michael, Traynelis, S. F. & Kastrup, Jette Sandholm Jensen, 2007, In : Proceedings of the National Academy of Science of the United States of America. 104, 35, p. 14116-14121

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Jagten på et signalstof til hjernens delta2-receptor

    Naur, P., Olsen, L., Gajhede, Michael & Kastrup, Jette Sandholm Jensen, 2007, In : Lægemiddelforskning. p. 32-33

    Research output: Contribution to journalJournal articleCommunication

  9. Published

    High resolution crystal structures of the p120 RasGAP SH3 domain

    Ross, B., Kristensen, O., Favre, D., Walicki, J., Kastrup, Jette Sandholm Jensen, Widmann, C. & Gajhede, Michael, 2007, In : Biochemical and Biophysical Research Communications. 353, 2, p. 463-468

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    A helical structural nucleus is the primary elongating unit of insulin amyloid fibrils

    Vestergaard, Bente, Jensen, M. G., Roessle, M., Kastrup, Jette Sandholm Jensen, van de Weert, Marco, Flink, J. M., Frøkjær, Sven, Gajhede, Michael & Svergun, D. I., 2007, In : PLoS - Biology. 5, 5, p. 1089-1097

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    A tetrazolyl-substituted subtype-selective AMPA receptor agonist

    Vogensen, S. B., Frydenvang, Karla Andrea, Greenwood, J. R., Postorino, G., Nielsen, Birgitte, Pickering, Darryl S, Ebert, B., Bølcho, U., Egebjerg, J., Gajhede, Michael, Kastrup, Jette Sandholm Jensen, Johansen, Tommy Nørskov, Clausen, Rasmus Prætorius & Krogsgaard-Larsen, Povl, 2007, In : Journal of Medicinal Chemistry. 50, 10, p. 2408-2414

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. 2006
  13. Published

    Structure of HLA-A*1101 in complex with a hepatitis B peptide homologue

    Blicher, T., Kastrup, Jette Sandholm Jensen, Pedersen, L. Ø., Buus, Søren & Gajhede, Michael, 2006, In : Acta Crystallographica Section F-Structural Biology and Crystallization Communications. 62, Pt 12, p. 1179-84 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    The structure of a mixed GluR2 ligand-binding core dimer in complex with (S)-glutamate and the antagonist (S)-NS1209

    Kasper, C., Pickering, Darryl S, Mirza, Osman Asghar, Olsen, L., Kristensen, Anders Skov, Greenwood, J. R., Liljefors, T., Schousboe, Arne, Wätjen, F., Gajhede, Michael, Sigurskjold, B. W. & Kastrup, Jette Sandholm Jensen, 2006, In : Journal of Molecular Biology. 357, 4, p. 1184-201 17 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    A unique set of SH3-SH3 interactions controls IB1 homodimerization

    Kristensen, O., Guenat, S., Dar, I., Allaman-Pillet, N., Abderrahmani, A., Ferdaoussi, M., Roduit, R., Maurer, F., Beckmann, J. S., Kastrup, Jette Sandholm Jensen, Gajhede, Michael & Bonny, C., 2006, In : E M B O Journal. 25, 4, p. 785-97 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    Structural rearrangements of sucrose phosphorylase from Bifidobacterium adolescentis during sucrose conversion

    Mirza, Osman Asghar, Henriksen, L. S., Sprogøe, D., van den Broek, L. A. M., Beldman, G., Kastrup, Jette Sandholm Jensen & Gajhede, Michael, 2006, In : Journal of Biological Chemistry. 281, 46, p. 35576-84 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Hvad har varme at gøre med lægemidler?

    Olsen, L., Kasper, C., Kastrup, Jette Sandholm Jensen, Gajhede, Michael & Jørgensen, Flemming Steen, 2006, In : Lægemiddelforskning. p. 31-33

    Research output: Contribution to journalJournal articleCommunication

  18. Published

    Crystal structures of two peptide-HLA-B*1501 complexes; structural characterization of the HLA-B62 supertype

    Røder, G., Blicher, T., Justesen, S., Johannesen, B., Kristensen, O., Kastrup, Jette Sandholm Jensen, Buus, Søren & Gajhede, Michael, 2006, In : Acta Crystallographica. Section D: Biological Crystallography. 62, Pt 11, p. 1300-10 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Structure of recombinant Ves v 2 at 2.0 Angstrom resolution: structural analysis of an allergenic hyaluronidase from wasp venom

    Skov, L. K., Seppälä, U., Coen, J. J. F., Crickmore, N., King, T. P., Monsalve, R., Kastrup, Jette Sandholm Jensen, Spangfort, M. D. & Gajhede, Michael, 2006, In : Acta Crystallographica. Section D: Biological Crystallography. 62, Pt 6, p. 595-604 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. 2005
  21. Published

    High-resolution structure of HLA-A*1101 in complex with SARS nucleocapsid peptide

    Blicher, T., Kastrup, Jette Sandholm Jensen, Buus, Søren & Gajhede, Michael, 2005, In : Acta Crystallographica. Section D: Biological Crystallography. 61, Pt 8, p. 1031-40 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Tyr702 is an important determinant of agonist binding and domain closure of the ligand-binding core of GluR2

    Frandsen, A., Pickering, Darryl S, Vestergaard, Bente, Kasper, C., Nielsen, B. B., Greenwood, J. R., Campiani, G., Fattorusso, C., Gajhede, Michael, Schousboe, Arne & Kastrup, Jette Sandholm Jensen, 2005, In : Molecular Pharmacology. 67, 3, p. 703-13 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Structural determinants of agonist-specific kinetics at the ionotropic glutamate receptor 2

    Holm, M. M., Lunn, M., Traynelis, S. F., Kastrup, Jette Sandholm Jensen & Egebjerg, J., 23 Aug 2005, In : Proceedings of the National Academy of Sciences of the United States of America. 102, 34, p. 12053-8 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Structure of the house dust mite allergen Der f 2: implications for function and molecular basis of IgE cross-reactivity

    Johannessen, B. R., Skov, L., Kastrup, Jette Sandholm Jensen, Kristensen, O., Bolwig, C., Larsen, J., Spangfort, M., Lund, K. & Gajhede, Michael, 2005, In : F E B S Letters. 579, 5, p. 1208-12 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Expression, crystallization and preliminary X-ray analysis of the extracellular Ig modules I-IV and F3 modules I-III of the neural cell-adhesion molecule L1

    Kulahin, N., Kasper, C., Kristensen, O., Kastrup, Jette Sandholm Jensen, Berezin, V., Bock, E. & Gajhede, Michael, 2005, In : Acta Crystallographica. Section F : Structural Biology and Crystallization Communications. 61, Pt 9, p. 858-60 2 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    Crystal structure of the kainate receptor GluR5 ligand-binding core in complex with (S)-glutamate

    Naur, P., Vestergaard, Bente, Skov, L., Egebjerg, J., Gajhede, Michael & Kastrup, Jette Sandholm Jensen, 2005, In : FEBS letters. 579, p. 1154-60

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Published

    Exploring the GluR2 ligand-binding core in complex with the bicyclical AMPA analogue (S)-4-AHCP

    Nielsen, B. B., Pickering, Darryl S, Greenwood, J. R., Brehm, L., Gajhede, Michael, Schousboe, Arne & Kastrup, Jette Sandholm Jensen, 2005, In : FEBS Journal. 272, 7, p. 1639-48 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. Published

    Crystal structure of a partly self-complementary peptide nucleic acid (PNA) oligomer showing a duplex-triplex network

    Petersson, B., Nielsen, B. B., Rasmussen, H., Larsen, I. K., Gajhede, Michael, Nielsen, Peter E. & Kastrup, Jette Sandholm Jensen, 9 Feb 2005, In : Journal of the American Chemical Society. 127, 5, p. 1424-30 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. Published

    The SAXS Solution Structure of RF1 Differs from Its Crystal Structure and Is Similar to Its Ribosome Bound Cryo-EM Structure

    Vestergaard, Bente, Sanyal, S., Roessle, M., Mora, L., Buckingham, R., Kastrup, Jette Sandholm Jensen, Gajhede, Michael, Svergun, D. I. & Ehrenberg, M., 2005, In : Molecular Cell. 20, p. 929-938

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. 2004
  31. Published

    Structural characterization of the stringent response related exopolyphosphatase/guanosine pentaphosphate phosphohydrolase protein family

    Kristensen, O., Laurberg, M., Liljas, A., Kastrup, Jette Sandholm Jensen & Gajhede, Michael, 2004, In : Biochemistry. 43, 28, p. 8894-900 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  32. Published

    Expression, crystallization and preliminary X-ray analysis of extracellular modules of the neural cell-adhesion molecules NCAM and L1

    Kulahin, N., Kasper, C., Gajhede, Michael, Berezin, V., Bock, E. & Kastrup, Jette Sandholm Jensen, Mar 2004, In : Acta Crystallographica. Section D: Biological Crystallography. 60, Pt 3, p. 591-3 3 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  33. Published

    Residue 182 influences the second step of protein-tyrosine phosphatase-mediated catalysis

    Pedersen, A. K., Guo, X., Møller, K. B., Peters, G. H., Andersen, H. S., Kastrup, Jette Sandholm Jensen, Mortensen, T. S., Iversen, L. F., Zhang, Z. & Møller, N. P. H., 1 Mar 2004, In : Biochemical Journal. 378, Pt 2, p. 421-33 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  34. Published

    Water-molecule network and active-site flexibility of apo protein tyrosine phosphatase 1B

    Pedersen, A. K., Peters G, G. Ü. H., Møller, K. B., Iversen, L. F. & Kastrup, Jette Sandholm Jensen, Sep 2004, In : Acta Crystallographica. Section D: Biological Crystallography. 60, Pt 9, p. 1527-34 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  35. Published

    The influence of a chiral amino acid on the helical handedness of PNA in solution and in crystals

    Rasmussen, H. B., Liljefors, T., Petersson, B., Nielsen, Peter E., Liljefors, T. & Kastrup, Jette Sandholm Jensen, Feb 2004, In : Journal of Biomolecular Structure & Dynamics. 21, 4, p. 495-502 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  36. Published

    Crystal structure of sucrose phosphorylase from Bifidobacterium adolescentis

    Sprogøe, D., van den Broek, L. A. M., Mirza, Osman Asghar, Kastrup, Jette Sandholm Jensen, Voragen, A. G. J., Gajhede, Michael & Skov, L., 10 Feb 2004, In : Biochemistry. 43, 5, p. 1156-62 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  37. 2003
  38. Published

    Competitive antagonism of AMPA receptors by ligands of different classes: crystal structure of ATPO bound to the GluR2 ligand-binding core, in comparison with DNQX

    Hogner, A., Greenwood, J. R., Liljefors, T., Lunn, M., Egebjerg, J., Larsen, I. K., Gouaux, E. & Kastrup, Jette Sandholm Jensen, 16 Jan 2003, In : Journal of Medicinal Chemistry. 46, 2, p. 214-21 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  39. Published

    Three-dimensional structure of the ligand-binding core of GluR2 in complex with the agonist (S)-ATPA: implications for receptor subunit selectivity

    Lunn, M., Hogner, A., Stensbøl, T. B., Gouaux, E., Egebjerg, J. & Kastrup, Jette Sandholm Jensen, 27 Feb 2003, In : Journal of Medicinal Chemistry. 46, 5, p. 872-5 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  40. Published

    Structure and interactions of NCAM Ig1-2-3 suggest a novel zipper mechanism for homophilic adhesion

    Soroka, V., Kolkova, K., Kastrup, Jette Sandholm Jensen, Diederichs, K., Breed, J., Kiselyov, V., Poulsen, F. M., Larsen, I. K., Welte, W., Berezin, V., Bock, E. & Kasper, C., 2003, In : Structure. 10, p. 1291-1301

    Research output: Contribution to journalJournal articleResearchpeer-review

  41. 2002
  42. Published

    Structural basis for AMPA receptor activation and ligand selectivity: crystal structures of five agonist complexes with the GluR2 ligand-binding core

    Hogner, A., Kastrup, Jette Sandholm Jensen, Jin, R., Liljefors, T., Mayer, M. L., Egebjerg, J., Larsen, I. K. & Gouaux, E., 6 Sep 2002, In : Journal of Molecular Biology. 322, 1, p. 93-109 17 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  43. Published

    GluR2 ligand-binding core complexes: importance of the isoxazolol moiety and 5-substituent for the binding mode of AMPA-type agonists

    Kasper, C., Lunn, M., Liljefors, T., Gouaux, E., Egebjerg, J. & Kastrup, Jette Sandholm Jensen, 6 Nov 2002, In : F E B S Letters. 531, 2, p. 173-8 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  44. 2000
  45. Published

    Structural basis of cell-cell adhesion by NCAM

    Kasper, C., Rasmussen, H., Kastrup, Jette Sandholm Jensen, Ikemizu, S., Jones, E. Y., Berezin, V., Bock, E. & Larsen, I. K., 2000, In : Nature Structural and Molecular Biology. 7, 5, p. 389-393 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  46. Published

    Lipopolysaccharide affinity measurement by scintillation proximity assay: application to human heparin binding protein

    Linde, V., Bjørn, S., Kastrup, Jette Sandholm Jensen & Flodgaard, H., Feb 2000, In : BioTechniques. 28, 2, p. 218-20, 222

    Research output: Contribution to journalJournal articleResearchpeer-review

  47. Published

    Measurement of apoptosis by the TUNEL method using scintillating microplates

    Linde, V., Flodgaard, H., Kastrup, Jette Sandholm Jensen & Bjørn, S., 10 Apr 2000, In : Analytical Biochemistry. 280, 1, p. 186-8 3 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  48. Published

    Crystallization and molecular-replacement solution of a truncated form of human recombinant tetranectin

    Nielsen, B. B., Kastrup, Jette Sandholm Jensen, Rasmussen, H. B., Graversen, J. H., Etzerodt, M., Thøgersen, H. C. & Larsen, I. K., May 2000, In : Acta Crystallographica. Section D: Biological Crystallography. 56, Pt 5, p. 637-9 3 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  49. 1999
  50. Published

    Peptide nucleic acids (PNA) derived from N-(N-methylamino-ethyl)glycine. Synthesis, hybridization and structural roperties

    Haaima, G., Rasmussen, H. B., Schmidt, G., Jensen, D. K., Kastrup, Jette Sandholm Jensen, Stafshede, P. W., Nordén, B., Buchardt, O. & Nielsen, Peter E., 1999, In : New. J. Chem.. 23, p. 833-840 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  51. Published

    Structure and function of the N-linked glycans of HBP/CAP37/azurocidin: crystal structure determination and biological characterization of nonglycosylated HBP

    Iversen, L. F., Kastrup, Jette Sandholm Jensen, Bjørn, S. E., Wiberg, F. C., Larsen, I. K., Flodgaard, H. J. & Rasmussen, P. B., Oct 1999, In : Protein Science. 8, 10, p. 2019-26 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  52. 1998
  53. Published

    Atomic resolution structure of human HBP/CAP37/Azurocidin

    Karlsen, S., Iversen, L. F., Larsen, I. K., Flodgaard, H. J. & Kastrup, Jette Sandholm Jensen, 1998, In : Acta Crystallographica. Section D: Biological Crystallography. 54, p. 598-609 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  54. Published

    Structure of the C-type lectin carbohydrate recognition domain of human Tetranectin

    Kastrup, Jette Sandholm Jensen, Nielsen, B. B., Rasmussen, H. B., Las Holtet, T., Graversen, J. H., Etzerodt, M., Thøgersen, H. C. & Larsen, I. K., 1998, In : Acta Crystallographica. Section D: Biological Crystallography. 54, p. 757-766 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  55. 1997
  56. Published

    Characterization of the allosteric binding pocket of human liver fructose-1,6-bisphosphatase by protein crystallography and inhibitor activity studies

    Iversen, L. F., Brzozowski, M., Hastrup, S., Larsen, I. K., Kastrup, Jette Sandholm Jensen, Nærum, L., Nørskov-Lauridsen, L., Rasmussen, P. B., Thim, L., Wiberg, F. C. & Lundgren, K., 1997, In : Protein Sci.. 6, p. 971-982 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  57. Published

    Structure of HBP, a multifunctional protein with a serine proteinase fold

    Iversen, L. F., Kastrup, Jette Sandholm Jensen, Bjørn, S. E., Wiberg, F. C., Flodgaard, H. J. & Larsen, I. K., 1997, In : Nature Struc. Biology. 4, p. 265-268 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  58. Published

    Human plasminogen binding protein tetranectin: crystallization and preliminary X-ray analysis of the C-type lectin CRD and the full-length protein

    Kastrup, Jette Sandholm Jensen, Rasmussen, H. B., Nielsen, B. B., Larsen, I. K., Las Holtet, T., Graversen, J. H., Etzerodt, M. & Thøgersen, H. C., 1997, In : Acta Crystallographica. Section D: Biological Crystallography. 53, p. 108-111 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  59. Published

    X-ray structure of the 154-amino-acid form of recombinant human basic fibroblast growth factor. Comparison with the truncated 146-amino-acid Form

    Kastrup, Jette Sandholm Jensen, Eriksson, E. S., Dalbøge, H. & Flodgaard, H., 1997, In : Acta Crystallographica. Section D: Biological Crystallography. 53, p. 160-168 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  60. Published

    Crystal structure of tetranectin, a trimeric plasminogen binding protein with an alpha-helical coiled coil

    Nielsen, B. B., Kastrup, Jette Sandholm Jensen, Rasmussen, H. B., Las Holtet, T., Graversen, J. H., Etzerodt, M., Thøgersen, H. C. & Larsen, I. K., 1997, In : FEBS Letters. 412, p. 388-396 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

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