Jette Sandholm Jensen Kastrup
Jette Sandholm Jensen Kastrup

Professor

  • Peptides and Proteins

    Jagtvej 162

    2100 København Ø

    Phone: +45 35 33 64 86

Introductory remarks on publicationslist


Publications 1988-2013 by Jette Sandholm Kastrup

Peer-reviewed: 93

    1990-1994: 4
    1995-1999: 12
    2000-2004: 17
    2005-2009: 37
    2010-May 2013: 23

Books (editor, chapters): 7
Patents: 2
Other publications: 28
PhD thesis: 1
Structures deposited in the Protein Data Bank: 106


  1. Published

    Crystallization and preliminary X-ray analysis of a PNA-DNA complex

    Kastrup, Jette Sandholm Jensen, Pilgaard, M., Jørgensen, Flemming Steen, Nielsen, Peter E. & Rasmussen, H. B., 1995, In : FEBS Letters. 363, p. 115-117 3 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Published

    L-Asp is a useful tool in the purification of the ionotropic glutamate receptor A2 ligand-binding domain

    Krintel, C., Frydenvang, Karla Andrea, Ceravalls de Rabassa, A., Kaern, A. M., Gajhede, Michael, Pickering, Darryl S & Kastrup, Jette Sandholm Jensen, 27 Mar 2014, In : F E B S Journal. p. 2422–2430 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Enthalpy-Entropy Compensation in the Binding of Modulators at Ionotropic Glutamate Receptor GluA2

    Krintel, C., Francotte, P., Pickering, Darryl S, Juknaite, L., Pøhlsgaaard, J., Olsen, L., Frydenvang, Karla Andrea, Goffin, E., Pirotte, B. & Kastrup, Jette Sandholm Jensen, 2016, In : Biophysical Journal. 110, 11, p. 2397-2406 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Structural analysis of the positive AMPA receptor modulators CX516 and Me-CX516 in complex with the GluA2 ligand-binding domain

    Krintel, C., Harpsøe, Kasper, Dorvil, Linda Grønborg, Peters, D., Frydenvang, Karla Andrea, Pickering, Darryl S, Gajhede, Michael & Kastrup, Jette Sandholm Jensen, 2013, In : Acta Crystallographica Section D: Structural Biology. 69, Pt 9, p. 1645-1652 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Thermodynamics and structural analysis of positive allosteric modulation of the ionotropic glutamate receptor GluA2

    Krintel, C., Frydenvang, Karla Andrea, Olsen, L., Kristensen, M. T., de Barrios, O., Naur, P., Francotte, P., Pirotte, B., Gajhede, Michael & Kastrup, Jette Sandholm Jensen, 1 Jan 2012, In : Biochemical Journal. 441, 1, p. 173-178

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Pharmacology and Structural Analysis of Ligand Binding to the Orthosteric Site of Glutamate-Like GluD2 Receptors

    Kristensen, Anders Skov, Hansen, K. B., Naur, P., Olsen, L., Kurtkaya, N. L., Dravid, S. M., Kvist, T., Yi, F., Pøhlsgaard, J., Clausen, Rasmus Prætorius, Gajhede, Michael, Kastrup, Jette Sandholm Jensen & Traynelis, S. F., Feb 2016, In : Molecular Pharmacology. 89, 2, p. 253-262 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Enzyme kinetic studies of histone demethylases KDM4C and KDM6A: Towards understanding selectivity of inhibitors targeting oncogenic histone demethylases

    Kristensen, J. B. L., Nielsen, A. L., Jørgensen, L., Kristensen, L. H., Helgstrand, C., Juknaite, L., Kristensen, Jesper Langgaard, Kastrup, Jette Sandholm Jensen, Clausen, Rasmus Prætorius, Olsen, L. & Gajhede, Michael, 23 Jun 2011, In : F E B S Letters. 585, 12, p. 1951-1956

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Studies of H3K4me3 demethylation by KDM5B/Jarid1B/PLU1 reveals strong substrate recognition in vitro and identifies 2,4-pyridine-dicarboxylic acid as an in vitro and in cell inhibitor

    Kristensen, L. H., Nielsen, A. L., Helgstrand, C., Lees, M., Cloos, Paul, Kastrup, Jette Sandholm Jensen, Helin, Kristian, Olsen, L. & Gajhede, Michael, Jun 2012, In : F E B S Journal. 279, 11, p. 1905-1914

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Structural characterization of the stringent response related exopolyphosphatase/guanosine pentaphosphate phosphohydrolase protein family

    Kristensen, O., Laurberg, M., Liljas, A., Kastrup, Jette Sandholm Jensen & Gajhede, Michael, 2004, In : Biochemistry. 43, 28, p. 8894-900 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Structure of a High-Affinity Kainate Receptor: GluK4 Ligand-Binding Domain Crystallized with Kainate

    Kristensen, O., Kristensen, L. B., Møllerud, Stine, Frydenvang, Karla Andrea, Pickering, Darryl S & Kastrup, Jette Sandholm Jensen, 2016, In : Structure. 24, 9, p. 1582-1589 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    A unique set of SH3-SH3 interactions controls IB1 homodimerization

    Kristensen, O., Guenat, S., Dar, I., Allaman-Pillet, N., Abderrahmani, A., Ferdaoussi, M., Roduit, R., Maurer, F., Beckmann, J. S., Kastrup, Jette Sandholm Jensen, Gajhede, Michael & Bonny, C., 2006, In : E M B O Journal. 25, 4, p. 785-97 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Structure-Activity Relationship Study of Ionotropic Glutamate Receptor Antagonist (2S,3R)-3-(3-Carboxyphenyl)pyrrolidine-2-carboxylic Acid

    Krogsgaard-Larsen, N., Storgaard, M., Møller, C., Demmer, C. S., Hansen, J., Han, L., Monrad, R. N., Nielsen, Birgitte, Tapken, D., Pickering, Darryl S, Kastrup, Jette Sandholm Jensen, Frydenvang, Karla Andrea & Bunch, Lennart, 2015, In : Journal of Medicinal Chemistry. 58, 15, p. 6131-50 20 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Crystal structure of NCAM2 IgIV-Fn3I

    Kulahin, N., Rasmussen, K. K., Kristensen, O., Kastrup, Jette Sandholm Jensen, Berezin, V., Bock, E. M., Walmod, P. S. & Gajhede, Michael, 2009

    Research output: Non-textual formDatasetResearch

  14. Published

    Expression, crystallization and preliminary X-ray analysis of the extracellular Ig modules I-IV and F3 modules I-III of the neural cell-adhesion molecule L1

    Kulahin, N., Kasper, C., Kristensen, O., Kastrup, Jette Sandholm Jensen, Berezin, V., Bock, E. & Gajhede, Michael, 2005, In : Acta Crystallographica. Section F : Structural Biology and Crystallization Communications. 61, Pt 9, p. 858-60 2 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Crystal Structure of NCAM2 Ig1 (I4122 Cell Unit)

    Kulahin, N., Rasmussen, K. K., Kristensen, O., Kastrup, Jette Sandholm Jensen, Poulsen, Jens-Christian Navarro, Berezin, V., Bock, E. M., Walmod, P. S. & Gajhede, Michael, 2008

    Research output: Non-textual formDatasetResearch

  16. Published

    Structure of rat acidic fibroblast growth factor at 1.4 A resolution.

    Kulahin, N., Kiselyov, V., Kochoyan, A., Kristensen, O., Kastrup, Jette Sandholm Jensen, Berezin, V., Bock, E. M. & Gajhede, Michael, 2007, In : Acta Crystallographica. Section F : Structural Biology and Crystallization Communications. 63, Pt2, p. 65-68 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Dimerization effect of sucrose octasulfate on rat FGF1.

    Kulahin, N., Kiselyov, V., Kochoyan, A., Kristensen, O., Kastrup, Jette Sandholm Jensen, Berezin, V., Bock, E. M. & Gajhede, Michael, 2008, In : Acta Crystallographica. Section F : Structural Biology and Crystallization Communications. 64, Pt6, p. 448-452 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Crystal structure of NCAM2 IgIV-Fn3II

    Kulahin, N., Rasmussen, K. K., Kristensen, O., Kastrup, Jette Sandholm Jensen, Berezin, V., Bock, E. M., Walmod, P. S. & Gajhede, Michael, 2009

    Research output: Non-textual formDatasetResearch

  19. Published

    Expression, crystallization and preliminary X-ray analysis of extracellular modules of the neural cell-adhesion molecules NCAM and L1

    Kulahin, N., Kasper, C., Gajhede, Michael, Berezin, V., Bock, E. & Kastrup, Jette Sandholm Jensen, Mar 2004, In : Acta Crystallographica. Section D: Biological Crystallography. 60, Pt 3, p. 591-3 3 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Structural model and trans-interaction of the entire ectodomain of the olfactory cell adhesion molecule

    Kulahin, N., Kristensen, O., Rasmussen, K. K., Olsen, L., Rydberg, P., Vestergaard, Bente, Kastrup, Jette Sandholm Jensen, Berezin, V., Bock, E., Walmod, P. S. & Gajhede, Michael, 9 Feb 2011, In : Structure. 19, 2, p. 203-211

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    Crystal structure and pharmacological characterization of a novel N-methyl-D-aspartate (NMDA) receptor antagonist at the GluN1 glycine binding site

    Kvist, T., Steffensen, T. B., Greenwood, J. R., Mehrzad Tabrizi, F., Hansen, K. B., Gajhede, Michael, Pickering, Darryl S, Traynelis, S. F., Kastrup, Jette Sandholm Jensen & Bräuner-Osborne, Hans, 2013, In : The Journal of Biological Chemistry. 288, p. 33124-35 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Synthesis and Pharmacology of Mono-, Di-, and Trialkyl-Substituted 7-Chloro-3,4-dihydro-2H-1,2,4-benzothiadiazine 1,1-Dioxides Combined with X-ray Structure Analysis to Understand the Unexpected Structure-Activity Relationship at AMPA Receptors

    Larsen, A. P., Francotte, P., Frydenvang, Karla Andrea, Tapken, D., Goffin, E., Fraikin, P., Caignard, D., Lestage, P., Danober, L., Pirotte, B. & Kastrup, Jette Sandholm Jensen, 16 Mar 2016, In : A C S Chemical Neuroscience. 7, 3, p. 378-90 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Lipopolysaccharide affinity measurement by scintillation proximity assay: application to human heparin binding protein

    Linde, V., Bjørn, S., Kastrup, Jette Sandholm Jensen & Flodgaard, H., Feb 2000, In : BioTechniques. 28, 2, p. 218-20, 222

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Measurement of apoptosis by the TUNEL method using scintillating microplates

    Linde, V., Flodgaard, H., Kastrup, Jette Sandholm Jensen & Bjørn, S., 10 Apr 2000, In : Analytical Biochemistry. 280, 1, p. 186-8 3 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Three-dimensional structure of the ligand-binding core of GluR2 in complex with the agonist (S)-ATPA: implications for receptor subunit selectivity

    Lunn, M., Hogner, A., Stensbøl, T. B., Gouaux, E., Egebjerg, J. & Kastrup, Jette Sandholm Jensen, 27 Feb 2003, In : Journal of Medicinal Chemistry. 46, 5, p. 872-5 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    Structural rearrangements of sucrose phosphorylase from Bifidobacterium adolescentis during sucrose conversion

    Mirza, Osman Asghar, Henriksen, L. S., Sprogøe, D., van den Broek, L. A. M., Beldman, G., Kastrup, Jette Sandholm Jensen & Gajhede, Michael, 2006, In : Journal of Biological Chemistry. 281, 46, p. 35576-84 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Published

    Targeting specific sub-domains of the GluA4 ionotropic glutamate receptor by murine Fab fragments

    Mohr, A. Ø., Riise, E. S., Pickering, Darryl S, Jensen, A. A., Madden, D., Kastrup, Jette Sandholm Jensen, Clausen, Rasmus Prætorius & Skottrup, P. D., 16 Jun 2011.

    Research output: Contribution to conferencePosterResearchpeer-review

  28. Published

    Establishment of an immunized murine Fab library for selection of iGluR6 binders by phage display

    Mohr, A. Ø., Skottrup, P. D., Jensen, A. A., Kastrup, Jette Sandholm Jensen, Clausen, Rasmus Prætorius & Riise, E. S., 28 May 2009.

    Research output: Contribution to conferencePosterResearch

  29. Published

    A pharmacological profile of the high-affinity GluK5 kainate receptor

    Møllerud, Stine, Kastrup, Jette Sandholm Jensen & Pickering, Darryl S, 2016, In : European Journal of Pharmacology. 788, p. 315-320 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. Published

    Jagten på et signalstof til hjernens delta2-receptor

    Naur, P., Olsen, L., Gajhede, Michael & Kastrup, Jette Sandholm Jensen, 2007, In : Lægemiddelforskning. p. 32-33

    Research output: Contribution to journalJournal articleCommunication

  31. Published

    Ionotropic glutamate-like receptor d2 binds D-serine and glycine.

    Naur, P., Hansen, K. B., Kristensen, Anders Skov, Dravid, S. M., Pickering, Darryl S, Olsen, L., Vestergaard, Bente, Egebjerg, J., Gajhede, Michael, Traynelis, S. F. & Kastrup, Jette Sandholm Jensen, 2007, In : Proceedings of the National Academy of Science of the United States of America. 104, 35, p. 14116-14121

    Research output: Contribution to journalJournal articleResearchpeer-review

  32. Published

    Crystal structure of the kainate receptor GluR5 ligand-binding core in complex with (S)-glutamate

    Naur, P., Vestergaard, Bente, Skov, L., Egebjerg, J., Gajhede, Michael & Kastrup, Jette Sandholm Jensen, 2005, In : FEBS letters. 579, p. 1154-60

    Research output: Contribution to journalJournal articleResearchpeer-review

  33. Published

    Crystallization and molecular-replacement solution of a truncated form of human recombinant tetranectin

    Nielsen, B. B., Kastrup, Jette Sandholm Jensen, Rasmussen, H. B., Graversen, J. H., Etzerodt, M., Thøgersen, H. C. & Larsen, I. K., May 2000, In : Acta Crystallographica. Section D: Biological Crystallography. 56, Pt 5, p. 637-9 3 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  34. Published

    Exploring the GluR2 ligand-binding core in complex with the bicyclical AMPA analogue (S)-4-AHCP

    Nielsen, B. B., Pickering, Darryl S, Greenwood, J. R., Brehm, L., Gajhede, Michael, Schousboe, Arne & Kastrup, Jette Sandholm Jensen, 2005, In : FEBS Journal. 272, 7, p. 1639-48 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  35. Published

    Crystal structure of tetranectin, a trimeric plasminogen binding protein with an alpha-helical coiled coil

    Nielsen, B. B., Kastrup, Jette Sandholm Jensen, Rasmussen, H. B., Las Holtet, T., Graversen, J. H., Etzerodt, M., Thøgersen, H. C. & Larsen, I. K., 1997, In : FEBS Letters. 412, p. 388-396 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  36. Published

    Thermodynamic Characterization of New Positive Allosteric Modulators Binding to the Glutamate Receptor A2 Ligand-Binding Domain: Combining Experimental and Computational Methods Unravels Differences in Driving Forces

    Nørholm, A., Francotte, P., Goffin, E., Botez, I., Danober, L., Lestage, P., Pirotte, B., Kastrup, Jette Sandholm Jensen, Olsen, L. & Oostenbrink, C., 22 Dec 2014, In : Journal of Chemical Information and Modeling. 54, 12, p. 3404-16 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  37. Published

    Synthesis, pharmacological and structural characterization, and thermodynamic aspects of GluA2-positive allosteric modulators with a 3,4-dihydro-2H-1,2,4-benzothiadiazine 1,1-dioxide scaffold

    Nørholm, A., Francotte, P., Olsen, L., Krintel, C., Frydenvang, Karla Andrea, Goffin, E., Challal, S., Danober, L., Botez-Pop, I., Lestage, P., Pirotte, B. & Kastrup, Jette Sandholm Jensen, 14 Nov 2013, In : Journal of Medicinal Chemistry. 56, 21, p. 8736-45 10 p.

    Research output: Contribution to journalJournal articleResearch

  38. Published

    Structural and functional studies of the modulator NS9283 reveal agonist-like mechanism of action at α4β2 nicotinic acetylcholine receptors

    Olsen, J. A., Ahring, P. K., Kastrup, Jette Sandholm Jensen, Gajhede, Michael & Balle, T., 5 Sep 2014, In : The Journal of Biological Chemistry. 289, 36, p. 24911-21 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  39. Published

    Two distinct allosteric binding sites at α4β2 nicotinic acetylcholine receptors revealed by NS206 and NS9283 give unique insights to binding activity-associated linkage at Cys-loop receptors.

    Olsen, J. A., Kastrup, Jette Sandholm Jensen, Peters, D., Gajhede, Michael, Balle, T. & Ahring, P. K., 13 Dec 2013, In : Journal of Biological Chemistry. 288, 50, p. 35997 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  40. Published

    Molecular recognition of the neurotransmitter acetylcholine by an acetylcholine binding protein reveals determinants of binding to nicotinic acetylcholine receptors

    Olsen, J. A., Balle, T., Gajhede, Michael, Ahring, P. K. & Kastrup, Jette Sandholm Jensen, 17 Mar 2014, In : PLOS ONE. 9, 3, p. e91232 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  41. Published

    Hvad har varme at gøre med lægemidler?

    Olsen, L., Kasper, C., Kastrup, Jette Sandholm Jensen, Gajhede, Michael & Jørgensen, Flemming Steen, 2006, In : Lægemiddelforskning. p. 31-33

    Research output: Contribution to journalJournal articleCommunication

  42. Published

    Neuroplastin-55 binds to and signals through the fibroblast growth factor receptor

    Owczarek, S., Kiryushko, D., Hald Larsen, M., Kastrup, Jette Sandholm Jensen, Gajhede, Michael, Sandi, C., Berezin, V., Bock, E. & Soroka, V., 2010, In : The FASEB Journal. 24, 4, p. 1139-1150 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  43. Published

    The structure of the complex between a branched pentasaccharide and Thermobacillus xylanilyticus GH-51 arabinofuranosidase reveals xylan-binding determinants and induced fit

    Paës, G., Skov, L. K., O'Donohue, M. J., Rémond, C., Kastrup, Jette Sandholm Jensen, Gajhede, Michael & Mirza, Osman Asghar, 2008, In : Biochemistry. 47, 28, p. 7441-7451

    Research output: Contribution to journalJournal articleResearchpeer-review

  44. Published

    Residue 182 influences the second step of protein-tyrosine phosphatase-mediated catalysis

    Pedersen, A. K., Guo, X., Møller, K. B., Peters, G. H., Andersen, H. S., Kastrup, Jette Sandholm Jensen, Mortensen, T. S., Iversen, L. F., Zhang, Z. & Møller, N. P. H., 1 Mar 2004, In : Biochemical Journal. 378, Pt 2, p. 421-33 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  45. Published

    Water-molecule network and active-site flexibility of apo protein tyrosine phosphatase 1B

    Pedersen, A. K., Peters G, G. Ü. H., Møller, K. B., Iversen, L. F. & Kastrup, Jette Sandholm Jensen, Sep 2004, In : Acta Crystallographica. Section D: Biological Crystallography. 60, Pt 9, p. 1527-34 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  46. Published

    Crystal structure of a partly self-complementary peptide nucleic acid (PNA) oligomer showing a duplex-triplex network

    Petersson, B., Nielsen, B. B., Rasmussen, H., Larsen, I. K., Gajhede, Michael, Nielsen, Peter E. & Kastrup, Jette Sandholm Jensen, 9 Feb 2005, In : Journal of the American Chemical Society. 127, 5, p. 1424-30 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  47. Published

    Lessons from more than 80 structures of the GluA2 ligand-binding domain in complex with agonists, antagonists and allosteric modulators

    Pøhlsgaard, J., Frydenvang, Karla Andrea, Madsen, Ulf & Kastrup, Jette Sandholm Jensen, 1 Jan 2011, In : Neuropharmacology. 60, 1, p. 135-150

    Research output: Contribution to journalReviewResearchpeer-review

  48. Published

    Crystal structure of a peptide nucleic acid (PNA) duplex at 1.7 Å resolution

    Rasmussen, H. B., Kastrup, Jette Sandholm Jensen, Nielsen, J. N., Nielsen, J. M. & Nielsen, Peter E., 1997, In : Nature Structural and Molecular Biology. 4, p. 98-101 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  49. Published

    The influence of a chiral amino acid on the helical handedness of PNA in solution and in crystals

    Rasmussen, H. B., Liljefors, T., Petersson, B., Nielsen, Peter E., Liljefors, T. & Kastrup, Jette Sandholm Jensen, Feb 2004, In : Journal of Biomolecular Structure & Dynamics. 21, 4, p. 495-502 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  50. Published

    Crystal structure of the Ig1 domain of the neural cell adhesion molecule NCAM2 displays domain swapping.

    Rasmussen, K. K., Kulahin, N., Kristensen, O., Poulsen, Jens-Christian Navarro, Sigurskjold, B. W., Kastrup, Jette Sandholm Jensen, Berezin, V., Bock, E., Walmod, P. S. & Gajhede, Michael, 2008, In : Journal of Molecular Biology. 382, 5, p. 1113-20 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

ID: 1298590