Karla Andrea Frydenvang

Karla Andrea Frydenvang

Associate Professor

Introductory remarks on publicationslist

See Homepage for complete list of publications (incl. all publications from before 2007)
  1. 2019
  2. Published

    Five-membered N-heterocyclic Scaffolds as Novel Amino Bioisosteres at -Aminobutyric Acid (GABA) Type A Receptors and GABA Transporters. / Giraudo, Alessandro; Krall, Jacob; Bavo, Francesco; Nielsen, Birgitte; Kongstad, Kenneth Thermann; Rolando, Barbara; De Blasio, Rosella; Gloriam, David E; Löffler, Rebekka; Thiesen, Louise; Harpsøe, Kasper; Frydenvang, Karla; Boschi, Donatella; Wellendorph, Petrine; Lolli, Marco L; Jensen, Anders A.; Frølund, Bente.

    In: Journal of Medicinal Chemistry, Vol. 62, No. 12, 27.06.2019, p. 5797-5809.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Design and Synthesis of 2,3-trans-Proline Analogs as Ligands for the Ionotropic Glutamate Receptors and the Excitatory Amino Acid Transporters. / Poulie, Christian Bernard Matthijs; Alcaide Lopez, Anna; Krell-Jørgensen, Mikkel Poul; Larsen, Younes; Astier, Eloi; Bjørn-Yoshimoto, Walden; Yi, Feng; Syrenne, Jed T; Storgaard, Morten; Nielsen, Birgitte; Frydenvang, Karla Andrea; Jensen, Anders A.; Hansen, Kasper B; Pickering, Darryl S; Bunch, Lennart.

    In: A C S Chemical Neuroscience, Vol. 10, No. 6, 19.06.2019, p. 2989-3007.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    N1-Substituted Quinoxaline-2,3-diones as Kainate Receptor Antagonists: X-ray Crystallography, Structure-Affinity Relationships and in vitro Pharmacology. / Pallesen, Jakob Staun; Møllerud, Stine; Frydenvang, Karla Andrea; Pickering, Darryl S; Bornholt, Jan; Nielsen, Birgitte; Pasini, Diletta; Han, Liwei; Marconi, Laura; Kastrup, Jette Sandholm Jensen; Johansen, Tommy Nørskov.

    In: A C S Chemical Neuroscience, Vol. 10, 20.03.2019, p. 1841-1853.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Crystal Structures of Potent Dimeric Positive Allosteric Modulators at the Ligand-Binding Domain of the GluA2 Receptor. / Laulumaa, Saara; Hansen, Kathrine Voigt; Masternak, Magdalena; Drapier, Thomas; Francotte, Pierre; Pirotte, Bernard; Frydenvang, Karla; Kastrup, Jette Sandholm.

    In: ACS Medicinal Chemistry Letters, Vol. 10, No. 3, 14.03.2019, p. 243-247.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Structural analysis of Cytochrome P450 BM3 mutant M11 in complex with dithiothreitol. / Frydenvang, Karla; Verkade-Vreeker, Marlies C A; Dohmen, Floor; Commandeur, Jan N M; Rafiq, Maria; Mirza, Osman; Jørgensen, Flemming Steen; Geerke, Daan P.

    In: PLoS ONE, Vol. 14, No. 5, 2019, p. e0217292.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. 2018
  8. Published

    (S)-2-Amino-3-(5-methyl-3-hydroxyisoxazol-4-yl)propanoic Acid (AMPA) and Kainate Receptor Ligands: Further Exploration of Bioisosteric Replacements, Structural and Biological Investigation. / Brogi, Simone; Brindisi, Marghertia; Butini, Stefania; Kshirsagar, Giridhar; Maramai, Samuele; Chemi, Giulia; Gemma, Sandra; Campiani, Giuseppe; Novellino, Ettore; Fiorenzani, Paolo; Pinassi, Jessica; Aloisi, Anna Maria; Gynther, Mikko; Venskutonyte, Raminta; Han, Liwei; Frydenvang, Karla Andrea; Kastrup, Jette Sandholm Jensen; Pickering, Darryl S.

    In: Journal of Medicinal Chemistry, Vol. 61, No. 5, 08.03.2018, p. 2124-2130.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    7-Phenoxy-Substituted 3,4-Dihydro-2H-1,2,4-benzothiadiazine 1,1-Dioxides as Positive Allosteric Modulators of α-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid (AMPA) Receptors with Nanomolar Potency. / Goffin, Eric; Drapier, Thomas; Larsen, Anja Probst; Geubelle, Pierre; Ptak, Christopher P; Laulumaa, Saara; Rovinskaja, Karoline; Gilissen, Julie; Tullio, Pascal de; Olsen, Lars; Frydenvang, Karla; Pirotte, Bernard; Hanson, Julien; Oswald, Robert E; Kastrup, Jette Sandholm; Francotte, Pierre.

    In: Journal of Medicinal Chemistry, Vol. 61, No. 1, 01.2018, p. 251–264.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. 2017
  11. Published

    Metformin, an Anthropogenic Contaminant of Seidlitzia rosmarinus Collected in a Desert Region near the Gulf of Aqaba, Sinai Peninsula. / Hassan, Ahmed R; El-Kousy, Salah M; El-Toumy, Sayed A; Frydenvang, Karla; Tung, Truong Thanh; Olsen, Jesper; Nielsen, John; Christensen, Søren Brøgger.

    In: Journal of Natural Products, Vol. 80, 27.10.2017, p. 2830-2834.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Pharmacology and crystal structure of novel 2,3-quinoxalinediones at kainate receptors. / Møllerud, Stine; Pallesen, Jakob Staun; Pasini, Diletta; Marconi, Laura; Han, Liwei; Bornholt, Jan; Johansen, Tommy Nørskov; Kastrup, Jette Sandholm ; Pickering, Darryl S; Frydenvang, Karla Andrea.

    In: Journal of Neurochemistry, Vol. 142, No. S1, MTU07-13, 08.2017, p. 124.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  13. Published

    Identification and Structure-Function Study of Positive Allosteric Modulators of Kainate Receptors. / Larsen, Anja Probst; Fièvre, Sabine; Frydenvang, Karla; Francotte, Pierre; Pirotte, Bernard; Kastrup, Jette Sandholm; Mulle, Christophe.

    In: Molecular Pharmacology, Vol. 91, No. 6, 06.2017, p. 576-585.

    Research output: Contribution to journalJournal articleResearchpeer-review

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