Karla Andrea Frydenvang
Karla Andrea Frydenvang

Associate Professor

Introductory remarks on publicationslist

See Homepage for complete list of publications (incl. all publications from before 2007)
  1. 1988
  2. Published

    Structures of acetylcholine picrate and methoxycarbonylcholine picrate hemihydrate

    Frydenvang, Karla Andrea, Grønborg, L. & Jensen, B., 1988, In : Acta Crystallographica. Section C: Crystal Structure Communications. 44, Pt 5, p. 841-5 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. 1994
  4. Published

    GABAB antagonists: resolution, absolute stereochemistry, and pharmacology of (R)- and (S)-phaclofen

    Frydenvang, Karla Andrea, Hansen, J. J., Krogsgaard-Larsen, Povl, Mitrovic, A., Tran, H., Drew, C. A. & Johnston, G. A., 1994, In : Chirality. 6, 7, p. 583-9 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Synthesis and structure-activity studies on acidic amino acids and related diacids as NMDA receptor ligands

    Johansen, Tommy Nørskov, Frydenvang, Karla Andrea, Ebert, B., Krogsgaard-Larsen, Povl & Madsen, Ulf, 1994, In : Journal of Medicinal Chemistry. 37, 20, p. 3252-62 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. 1995
  7. Published

    GABA-B Antagonists: Enantiopharmacology of 5-Amino-4-hydroxy-2-methylvaleric Acid and X-Ray Structure of the Eutomer

    Frydenvang, Karla Andrea, Kristiansen, Uffe, Frølund, Bente, Herdeis, C. & Krogsgaard-Larsen, Povl, 1995, In : Chirality. 7, p. 526–533

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. 1996
  9. Published

    Conformational analysis of acetylcholine and related choline esters

    Frydenvang, Karla Andrea & Jensen, B., 1996, In : Acta Crystallographica. Section B: Structural Science. 52 ( Pt 1), p. 184-93 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    N-methyl-D-aspartic acid receptor agonists: resolution, absolute stereochemistry, and pharmacology of the enantiomers of 2-amino-2-(3-hydroxy-5-methyl-4-isoxazolyl)acetic acid

    Madsen, Ulf, Frydenvang, Karla Andrea, Ebert, B., Johansen, Tommy Nørskov, Brehm, L. & Krogsgaard-Larsen, Povl, 1996, In : Journal of Medicinal Chemistry. 39, 1, p. 183-90 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Stereospecific GABA-B receptor antagonism

    Frydenvang, Karla Andrea, Frølund, Bente, Kristiansen, Uffe & Krogsgaard-Larsen, Povl, 1996, GABA, receptors, transporters and metabolism. Tanaka, C. & Bowery, N. G. (eds.). Basel: Birkhäuser Verlag

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  12. 1997
  13. Published

    Antiprotozoal compounds from Asparagus africanus

    Oketch-Rabah, H. A., Dossaji, S. F., Christensen, S. B., Frydenvang, Karla Andrea, Lemmich, E., Cornett, Claus, Olsen, C. E., Chen, M., Kharazmi, A. & rvx529, rvx529, 1997, In : Journal of Natural Products. 60, 10, p. 1017-22 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published
  15. Published

    GABA-A and GABA-B receptor Agonists, Partial Agonists and Modulators. design and Therapeutic Prospects

    Frølund, Bente, Krogsgaard-Larsen, Povl, Kristiansen, Uffe, Frydenvang, Karla Andrea & Ebert, B., 1997, In : European Journal of Pharmaceutical Sciences. 4, p. 355–384

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. 1998
  17. Published

    Antiprotozoal properties of 16,17-dihydrobrachycalyxolide from Vernonia brachycalyx

    Oketch-Rabah, H. A., Christensen, Søren Brøgger, Frydenvang, Karla Andrea, Dossaji, S. F., rvx529, rvx529, Cornett, Claus, Watkins, W. M., Kharazmi, A. & Lemmich, E., 1998, In : Planta Medica. 64, 6, p. 559-62 3 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    UV-Guided isolation of alantrypinone, a novel Penicillium alkaloid

    Larsen, T. O., Frydenvang, Karla Andrea, Frisvad, J. C. & Christophersen, C., 1998, In : Journal of Natural Products. 61, 9, p. 1154-7 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. 1999
  20. Published

    Selective Inhibitors of Glial GABA Uptake: Synthesis, Absolute Stereochemistry, and Pharmacology of the Enantiomers of 3-Hydroxy-4-amino-4,5,6,7-tetrahydro-1,2-benzisoxazole (exo-THPO) and Analogues

    Falch, E., Frølund, Bente, Perregaard, Sanchez, C., Søkilde, B., Buur, A., Hansen, A., Frydenvang, Karla Andrea, Brehm, L., Bolvig, T., Larsson, O. M., Schousboe, Arne & Krogsgaard-Larsen, Povl, 1999, In : Journal of Medicinal Chemistry. 42, p. 5402–5414

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    Synthesis and muscarinic receptor pharmacology of a series of 4,5,6,7-tetrahydroisothiazolo[4,5-c]pyridine bioisosteres of arecoline

    Pedersen, H., Bräuner-Osborne, Hans, Ball, R. G., Frydenvang, Karla Andrea, Meier, E., Bøgesø, K. P. & Krogsgaard-Larsen, Povl, 1999, In : Bioorganic & Medicinal Chemistry. 7, 5, p. 795-809 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. 2000
  23. Published

    GABA uptake inhibitors. Design, molecular pharmacology and therapeutic aspects

    Krogsgaard-Larsen, Povl, Frølund, Bente & Frydenvang, Karla Andrea, 2000, In : Current Pharmaceutical Design. 6, 12, p. 1193-209 17 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Resolution, configurational assignment, and enantiopharmacology of 2-amino-3-[3-hydroxy-5-(2-methyl-2H- tetrazol-5-yl)isoxazol-4-yl]propionic acid, a potent GluR3- and GluR4-preferring AMPA receptor agonist

    Vogensen, S. B., Jensen, H. S., Stensbøl, T. B., Frydenvang, Karla Andrea, Bang-Andersen, B., Johansen, Tommy Nørskov, Egebjerg, J. & Krogsgaard-Larsen, Povl, 2000, In : Chirality. 12, 10, p. 705-13 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    UV-guided screening of benzodiazepine producing species in Penicillium

    Ostenfeld Larsen T, Frydenvang, Karla Andrea & Christian Frisvad J, 2000, In : Biochemical Systematics and Ecology. 28, 9, p. 881-886 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. 2001
  27. Published
  28. Published

    Stereochemistry and molecular pharmacology of (S)-thio-ATPA, a new potent and selective GluR5 agonist

    Stensbøl, T. B., Jensen, H. S., Nielsen, Birgitte, Johansen, Tommy Nørskov, Egebjerg, J., Frydenvang, Karla Andrea & Krogsgaard-Larsen, Povl, 2001, In : European Journal of Pharmacology. 411, 3, p. 245-53 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. Published

    Synthesis and pharmacology of 3-isoxazolol amino acids as selective antagonists at group I metabotropic glutamic acid receptors

    Madsen, Ulf, Bräuner-Osborne, Hans, Frydenvang, Karla Andrea, Hvene, L., Johansen, Tommy Nørskov, Nielsen, Birgitte, Sánchez, C., Stensbøl, T. B., Bischoff, F. & Krogsgaard-Larsen, Povl, 2001, In : Journal of Medicinal Chemistry. 44, 7, p. 1051-9 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. Published

    Unprecedented migration of N-alkoxycarbonyl groups in protected pyroglutaminol

    Bunch, Lennart, Norrby, P., Frydenvang, Karla Andrea, Krogsgaard-Larsen, Povl & Madsen, Ulf, 2001, In : Organic Letters. 3, 3, p. 433-5 3 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  31. 2002
  32. Published

    2-Amino-3-(3-hydroxy-1,2,5-thiadiazol-4-yl)propionic acid: resolution, absolute stereochemistry and enantiopharmacology at glutamate receptors

    Johansen, Tommy Nørskov, Janin, Y. L., Nielsen, Birgitte, Frydenvang, Karla Andrea, Bräuner-Osborne, Hans, Stensbøl, T. B., Vogensen, S. B., Madsen, Ulf & Krogsgaard-Larsen, Povl, 2002, In : Bioorganic & Medicinal Chemistry. 10, 7, p. 2259-66 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  33. Published

    Correlation of aqueous solubility of salts of benzylamine with experimentally and theoretically derived parameters. A multivariate data analysis approach

    Parshad, H., Frydenvang, Karla Andrea, Liljefors, T. & Larsen, C. S., 2002, In : International Journal of Pharmaceutics. 237, 1-2, p. 193-207 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  34. Published

    Glutamate receptor ligands: synthesis, stereochemistry, and enantiopharmacology of methylated 2-aminoadipic acid analogs

    Guldbrandt, M., Johansen, Tommy Nørskov, Frydenvang, Karla Andrea, Bräuner-Osborne, Hans, Stensbøl, T. B., Nielsen, Birgitte, Karla, R., Santi, F., Krogsgaard-Larsen, Povl & Madsen, Ulf, 2002, In : Chirality. 14, 4, p. 351-63 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  35. Plant analysis by butterflies: occurrence of cyclopentenylglycines in Passifloraceae, Flacourtiaceae, and Turneraceae and discovery of the novel nonproteinogenic amino acid 2-(3'-cyclopentenyl)glycine in Rinorea

    Clausen, V., Frydenvang, Karla Andrea, Koopmann, R., Jørgensen, L. B., Abbiw, D. K., Ekpe, P. & Jaroszewski, J. W., 2002, In : Journal of Natural Products. 65, 4, p. 542-7 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  36. 2003
  37. Published

    Assessment of drug salt release from solutions, suspensions and in situ suspensions using a rotating dialysis cell

    Parshad, H., Frydenvang, Karla Andrea, Liljefors, T., Cornett, Claus & Larsen, C., 2003, In : European Journal of Pharmaceutical Sciences. 19, 4, p. 263-272 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  38. Published

    Rational design, synthesis, and pharmacological evaluation of 2-azanorbornane-3-exo,5-endo-dicarboxylic acid: a novel conformationally restricted glutamic acid analogue

    Bunch, Lennart, Liljefors, T., Greenwood, J. R., Frydenvang, Karla Andrea, Bräuner-Osborne, Hans, Krogsgaard-Larsen, Povl & Madsen, Ulf, 2003, In : Journal of Organic Chemistry. 68, 4, p. 1489-95 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  39. Published

    Stereostructure-activity studies on agonists at the AMPA and kainate subtypes of ionotropic glutamate receptors

    Johansen, Tommy Nørskov, Greenwood, J. R., Frydenvang, Karla Andrea, Madsen, Ulf & Krogsgaard-Larsen, Povl, 2003, In : Chirality. 15, 2, p. 167-79 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  40. 2004
  41. Published

    2-(2,3-Dihydro-1H-indol-3-yl)ethanol: synthesis, separation of enantiomers, and assignment of absolute stereochemistry by X-ray structure analysis

    Frydenvang, Karla Andrea, Sommer, M. B., Heckmann, D., Nielsen, O. & Bang-Andersen, B., 2004, In : Chirality. 16, 2, p. 126-30 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  42. Published

    Aqueous solubility study of salts of benzylamine derivatives and p-substituted benzoic acid derivatives using X-ray crystallographic analysis

    Parshad, H., Frydenvang, Karla Andrea, Liljefors, T., Sorensen, H. O. & Larsen, C., 2004, In : International Journal of Pharmaceutics. 269, 1, p. 157-68 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  43. Published

    Carbamoylcholine homologs: synthesis and pharmacology at nicotinic acetylcholine receptors

    Jensen, Anders A., Mikkelsen, I. B., Frølund, Bente, Frydenvang, Karla Andrea, Brehm, L., Jaroszewski, J. W., Bräuner-Osborne, Hans, Falch, E. & Krogsgaard-Larsen, Povl, 2004, In : European Journal of Pharmacology. 497, 2, p. 125-37 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  44. Published

    Psychrophilin A and Cycloaspeptide D, novel cyclic peptides from the psychrotolerant fungus Penicillium ribeum

    Dalsgaard, P. W., Larsen, T. O., Frydenvang, Karla Andrea & Christophersen, C., 2004, In : Journal of Natural Products. 67, 5, p. 878-881

    Research output: Contribution to journalJournal articleResearchpeer-review

  45. Published

    Design, synthesis, and pharmacological characterization of novel, potent NMDA receptor antagonists

    Conti, P., De Amici, M., Grazioso, G., Roda, G., Barberis Negra, F. F., Nielsen, Birgitte, Stensbøl, T. B., Madsen, Ulf, Bräuner-Osborne, Hans, Frydenvang, Karla Andrea, De Sarro, G., Toma, L. & De Micheli, C., 30 Dec 2004, In : Journal of Medicinal Chemistry. 47, 27, p. 6740-8 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  46. 2005
  47. Published

    Andrastin A and barceloneic acid metabolites, protein farnesyl transferase inhibitors from Penicillium albocoremium: chemotaxonomic significance and pathological implications

    Overy, D. P., Larsen, T. O., Dalsgaard, P. W., Frydenvang, Karla Andrea, Phipps, R., Munro, M. H. G. & Christophersen, C., 2005, In : Mycological Research. 109, p. 1243-1249

    Research output: Contribution to journalJournal articleResearchpeer-review

  48. Published

    Assessment of the combined approach of N-alkylation and salt formation to enhance aqueous solubility of tertiary amines using bupivacaine as a model drug

    Nielsen, A. B., Frydenvang, Karla Andrea, Liljefors, T., Buur, A. & Larsen, C., 2005, In : European Journal of Pharmaceutical Sciences. 24, 1, p. 85-93 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  49. 2006
  50. Published

    Sesquiterpenes from Thapsia nitida var. meridionalis and Thapsia nitida var. nitida

    Rubal, J. J., Guerra, F. M., Moreno-Dorado, F. J., Jorge, Z. D., Massanet, G. M., Søhoel, H., Smitt, U. W., Frydenvang, Karla Andrea, Christensen, Søren Brøgger, Nielsen, C. & Eriksson, M., 2006, In : Journal of Natural Products. 69, 11, p. 1566-71 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  51. 2007
  52. Published

    A tetrazolyl-substituted subtype-selective AMPA receptor agonist

    Vogensen, S. B., Frydenvang, Karla Andrea, Greenwood, J. R., Postorino, G., Nielsen, Birgitte, Pickering, Darryl S, Ebert, B., Bølcho, U., Egebjerg, J., Gajhede, Michael, Kastrup, Jette Sandholm Jensen, Johansen, Tommy Nørskov, Clausen, Rasmus Prætorius & Krogsgaard-Larsen, Povl, 2007, In : Journal of Medicinal Chemistry. 50, 10, p. 2408-2414

    Research output: Contribution to journalJournal articleResearchpeer-review

  53. Published

    Synthesis and pharmacological evaluation of novel conformationally constrained homologues of glutamic acid

    Conti, P., Caligiuri, A., Pinto, A., Roda, G., Tamborini, L., Nielsen, Birgitte, Madsen, Ulf, Frydenvang, Karla Andrea, Colombo, A. & De Micheli, C., 2007, In : European Journal of Medicinal Chemistry. 42, 8, p. 1059-1068

    Research output: Contribution to journalJournal articleResearchpeer-review

  54. 2008
  55. Published

    Microwave-Assisted Ring-Opening of Activated Aziridines with Resin-Bound Amines

    Crestey, F. L. J., Witt, M., Frydenvang, Karla Andrea, Stærk, Dan, Jaroszewski, J. & Franzyk, Henrik, 2008, In : Synfacts. 7, p. 769 1 p.

    Research output: Contribution to journalJournal articleResearch

  56. Published

    Microwave-assisted ring-opening of activated aziridines with resin-bound amines

    Crestey, F., Witt, M., Frydenvang, Karla Andrea, Stærk, Dan, Jaroszewski, J. W. & Franzyk, Henrik, 2008, In : Journal of Organic Chemistry. 73, 9, p. 3566-3569 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  57. Published

    Molecular mechanism of agonist recognition by the ligand-binding core of the ionotropic glutamate receptor 4

    Kasper, C., Frydenvang, Karla Andrea, Naur, P., Gajhede, Michael, Pickering, Darryl S & Kastrup, Jette Sandholm Jensen, 2008, In : FEBS Letters. 582, 29, p. 4089-4094

    Research output: Contribution to journalJournal articleResearchpeer-review

  58. Published

    Novel high-affinity and selective biaromatic 4-substituted ¿-hydroxybutyric acid (GHB) analogues as GHB ligands: design, synthesis, and binding studies

    Høg, S., Wellendorph, Petrine, Nielsen, Birgitte, Frydenvang, Karla Andrea, Dahl, I. F., Bräuner-Osborne, Hans, Brehm, L., Frølund, Bente & Clausen, Rasmus Prætorius, 2008, In : Journal of Medicinal Chemistry. 51, 24, p. 8088-8095

    Research output: Contribution to journalJournal articleResearchpeer-review

  59. 2009
  60. Published

    At være eller ikke være en antagonist

    Frydenvang, Karla Andrea, Naur, P., Gajhede, Michael & Kastrup, Jette Sandholm Jensen, 2009, In : Lægemiddelforskning. p. 43-45

    Research output: Contribution to journalJournal articleCommunication

  61. Published

    Full domain closure of the ligand-binding core of the ionotropic glutamate receptor iGluR5 induced by the high affinity agonist dysiherbaine and the functional antagonist 8,9-dideoxyneodysiherbaine

    Frydenvang, Karla Andrea, Lash, L. L., Naur, P., Postila, P. A., Pickering, Darryl S, Smith, C. M., Gajhede, Michael, Sasaki, M., Sakai, R., Pentikäinen, O. T., Swanson, G. T. & Kastrup, Jette Sandholm Jensen, 2009, In : Journal of Biological Chemistry. 284, 21, p. 14219-14229

    Research output: Contribution to journalJournal articleResearchpeer-review

  62. Published

    New analogues of epiboxidine incorporating the 4,5-dihydroisoxazole nucleus: synthesis, binding affinity at neuronal nicotinic acetylcholine receptors, and molecular modeling investigations

    Dallanoce, C., Magrone, P., Bazza, P., Grazioso, G., Rizzi, L., Riganti, L., Gotti, C., Clementi, F., Frydenvang, Karla Andrea & De Amici, M., 2009, In : Chemistry & Biodiversity. 6, 2, p. 244-259

    Research output: Contribution to journalJournal articleResearchpeer-review

  63. Published

    Structural characterisation and dehydration behaviour of siramesine hydrochloride

    Zimmermann, A., Tian, F., Lopez de Diego, H., Frydenvang, Karla Andrea, Rantanen, Jukka, Elema, M. R. & Hovgaard, L., 2009, In : Journal of Pharmaceutical Sciences. 98, 10, p. 3596-3607

    Research output: Contribution to journalJournal articleResearchpeer-review

  64. 2010
  65. Published

    Structure-activity relationship study of first selective inhibitor of excitatory amino acid transporter subtype 1: 2-amino-4-(4-methoxyphenyl)-7-(naphthalen-1-yl)-5-oxo-5,6,7,8-tetrahydro-4H-chromene-3-carbonitrile (UCPH-101)

    Erichsen, M. N., Huynh, T. H. V., Abrahamsen, B., Bastlund, J. F., Bundgaard, C., Monrad, O., Bekker-Jensen, A., Nielsen, C. W., Frydenvang, Karla Andrea, Jensen, Anders A. & Bunch, Lennart, 2010, In : Journal of Medicinal Chemistry. 53, 19, p. 7180–7191

    Research output: Contribution to journalJournal articleResearchpeer-review

  66. Published

    Structure-activity relationships of a small-molecule inhibitor of the PDZ domain of PICK1

    Bach, Anders, Stuhr-Hansen, N., Thorsen, Thor Seneca, Bork, N., Moreira, I. S., Frydenvang, Karla Andrea, Padrah, S., Christensen, Søren Brøgger, Madsen, Kenneth Lindegaard, Weinstein, H., Gether, Ulrik & Strømgaard, Kristian, 2010, In : Organic & Biomolecular Chemistry. 8, 19, p. 4281-4288 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  67. Published

    Synthesis and characterization of an epimer of tacrolimus, an immunosuppressive drug

    Skytte, D. M., Frydenvang, Karla Andrea, Hansen, L., Nielsen, P. G. & Jaroszewski, J. W., 18 Feb 2010, In : Journal of Natural Products. 73, 4, p. 776-779

    Research output: Contribution to journalJournal articleResearchpeer-review

  68. Published

    Synthesis and antitumor effect in vitro and in vivo of substituted 1,3-dihydroindole-2-ones

    Christensen, M. K., Erichsen, K. D., Trojel-Hansen, C., Tjørnelund, J., Nielsen, S. J., Frydenvang, Karla Andrea, Johansen, Tommy Nørskov, Nielsen, Birgitte, Sehested, M., Jensen, P. B., Ikaunieks, M., Zaichenko, A., Loza, E., Kalvinsh, I. & Björkling, Fredrik, 14 Oct 2010, In : Journal of Medicinal Chemistry. 53, 19, p. 7140-7145 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  69. Published

    Solid forms of amlodipine besylate: Physiochemical, structural, and thermodynamic characterization

    Koradia, V. S., Lopez de Diego, H., Frydenvang, Karla Andrea, Ringkjøbing-Elema, M., Mullertz, Anette , Bond, A. D. & Rantanen, Jukka, 28 Oct 2010, In : Crystal Growth & Design. 10, 12, p. 5279-5290

    Research output: Contribution to journalJournal articleResearchpeer-review

  70. Published

    Biostructural and pharmacological studies of bicyclic analogues of the 3-isoxazolol glutamate receptor agonist ibotenic acid

    Frydenvang, Karla Andrea, Pickering, Darryl S, Greenwood, J. R., Krogsgaard-Larsen, N., Brehm, L., Nielsen, Birgitte, Vogensen, S. B., Hald, H., Kastrup, Jette Sandholm Jensen, Krogsgaard-Larsen, Povl & Clausen, Rasmus Prætorius, 10 Nov 2010, In : Journal of Medicinal Chemistry. 53, 23, p. 8354-8361

    Research output: Contribution to journalJournal articleResearchpeer-review

  71. Published

    Syntheses of aza-analogous iso-ergoline scaffolds using carbene mediated C-H insertion

    Krogsgaard-Larsen, N., Begtrup, M., Frydenvang, Karla Andrea & Kehler, J., 20 Nov 2010, In : Tetrahedron. 66, 47, p. 9297-9303

    Research output: Contribution to journalJournal articleResearchpeer-review

  72. 2011
  73. Published

    Lessons from more than 80 structures of the GluA2 ligand-binding domain in complex with agonists, antagonists and allosteric modulators

    Pøhlsgaard, J., Frydenvang, Karla Andrea, Madsen, Ulf & Kastrup, Jette Sandholm Jensen, 1 Jan 2011, In : Neuropharmacology. 60, 1, p. 135-150

    Research output: Contribution to journalReviewResearchpeer-review

  74. Published

    Design, synthesis, and pharmacological characterization of novel spirocyclic quinuclidinyl-Delta2 -isoxazoline derivatives as potent and selective agonists of alpha7 nicotinic acetylcholine receptors

    Dallanoce, C., Magrone, P., Matera, C., Frigerio, F., Grazioso, G., De Amici, M., Fucile, S., Piccari, V., Frydenvang, Karla Andrea, Pucci, L., Gotti, C., Clementi, F. & De Micheli, C., 2 May 2011, In : ChemMedChem. 6, 5, p. 889-903

    Research output: Contribution to journalJournal articleResearchpeer-review

  75. Published

    Selective kainate receptor (GluK1) ligands structurally based upon1H-Cyclopentapyrimidin-2,4(1H,3H)-dione: synthesis, molecular modeling, and pharmacological and biostructural characterization

    Venskutonyte, R., Butini, S., Coccone, S. S., Gemma, S., Brindisi, M., Kumar, V., Guarino, E., Maramai, S., Valenti, S., Amir, A., Valades, E. A., Frydenvang, Karla Andrea, Kastrup, Jette Sandholm Jensen, Novellino, E., Campiani, G. & Pickering, Darryl S, 14 Jul 2011, In : Journal of Medicinal Chemistry. 54, 13, p. 4793-4805

    Research output: Contribution to journalJournal articleResearchpeer-review

  76. Published

    A new phenylalanine derivative acts as an antagonist at the AMPA receptor GluA2 and introduces partial domain closure: Synthesis, resolution, pharmacology, and crystal structure

    Szymanska, E., Frydenvang, Karla Andrea, Contreras-Sanz, A., Pickering, Darryl S, Frola, E., Serafimoska, Z., Nielsen, Birgitte, Kastrup, Jette Sandholm Jensen & Johansen, Tommy Nørskov, 4 Oct 2011, In : Journal of Medicinal Chemistry. 54, 20, p. 7289-7298

    Research output: Contribution to journalJournal articleResearchpeer-review

  77. Published
  78. 2012
  79. Published

    Pharmacological and structural characterization of conformationally restricted (S)-glutamate analogues at ionotropic glutamate receptors

    Juknaite, L., Venskutonyte, R., Assaf, Z., Faure, S., Gefflaut, T., Aitken, D. J., Nielsen, Birgitte, Gajhede, Michael, Kastrup, Jette Sandholm Jensen, Bunch, Lennart, Frydenvang, Karla Andrea & Pickering, Darryl S, 2012, In : Journal of Structural Biology. 180, 1, p. 39-46

    Research output: Contribution to journalJournal articleResearchpeer-review

  80. Published

    Thermodynamics and structural analysis of positive allosteric modulation of the ionotropic glutamate receptor GluA2

    Krintel, C., Frydenvang, Karla Andrea, Olsen, L., Kristensen, M. T., de Barrios, O., Naur, P., Francotte, P., Pirotte, B., Gajhede, Michael & Kastrup, Jette Sandholm Jensen, 1 Jan 2012, In : Biochemical Journal. 441, 1, p. 173-178

    Research output: Contribution to journalJournal articleResearchpeer-review

  81. Published

    Kainate induces various domain closures in AMPA and kainate receptors

    Venskutonyte, R., Frydenvang, Karla Andrea, Hald, H., Rabassa, A. C. D., Gajhede, Michael, Ahring, P. K. & Kastrup, Jette Sandholm Jensen, Sep 2012, In : Neurochemistry International. 61, 4, p. 536-545

    Research output: Contribution to journalJournal articleResearchpeer-review

  82. Published

    Structural and pharmacological characterization of phenylalanine-based AMPA receptor antagonists at kainate receptors

    Venskutonyte, R., Frydenvang, Karla Andrea, Valadés, E. A., Szymanska, E. M., Johansen, Tommy Nørskov, Kastrup, Jette Sandholm Jensen & Pickering, Darryl S, Oct 2012, In : ChemMedChem. 7, 10, p. 1793-1798 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  83. 2013
  84. Published

    Chemo-enzymatic synthesis of new 2,4-syn-functionalized (S)-glutamate analogues and structure-activity relationship studies at ionotropic glutamate receptors and excitatory amino acid transporters

    Assaf, Z., Larsen, A. P., Venskutonyte, R., Han, L., Abrahamsen, B., Nielsen, Birgitte, Gajhede, Michael, Kastrup, Jette Sandholm Jensen, Jensen, Anders A., Pickering, Darryl S, Frydenvang, Karla Andrea, Gefflaut, T. & Bunch, Lennart, 2013, In : Journal of Medicinal Chemistry. 56, 4, p. 1614-1628

    Research output: Contribution to journalJournal articleResearchpeer-review

  85. Published

    På jagt efter et virkningssted i hjernen

    Frydenvang, Karla Andrea, Juknaite, L. & Kastrup, Jette Sandholm Jensen, 2013, In : Lægemiddelforskning. p. 50-52 3 p.

    Research output: Contribution to journalJournal articleCommunication

  86. Published

    Some transformations of tacrolimus, an immunosuppressive drug

    Skytte, D. M., Jaroszewski, J. W., Kongstad, Kenneth Thermann, Hansen, S. H., Hansen, L., G. Nielsen, P. & Frydenvang, Karla Andrea, 2013, In : European Journal of Pharmaceutical Sciences. 48, 3, p. 514-522 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  87. Published

    Structural analysis of the positive AMPA receptor modulators CX516 and Me-CX516 in complex with the GluA2 ligand-binding domain

    Krintel, C., Harpsøe, Kasper, Dorvil, Linda Grønborg, Peters, D., Frydenvang, Karla Andrea, Pickering, Darryl S, Gajhede, Michael & Kastrup, Jette Sandholm Jensen, 2013, In : Acta Crystallographica Section D: Structural Biology. 69, Pt 9, p. 1645-1652 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  88. Published

    Studies on an (S)-2-amino-3-(3-hydroxy-5-methyl-4-isoxazolyl)propionic acid (AMPA) receptor antagonist IKM-159: asymmetric synthesis, neuroactivity, and structural characterization

    Juknaite, L., Sugamata, Y., Tokiwa, K., Ishikawa, Y., Takamizawa, S., Eng, A., Sakai, R., Pickering, Darryl S, Frydenvang, Karla Andrea, Swanson, G. T., Kastrup, Jette Sandholm Jensen & Oikawa, M., 2013, In : Journal of Medicinal Chemistry. 56, 6, p. 2283-2293

    Research output: Contribution to journalJournal articleResearchpeer-review

  89. Published

    Synthesis and biological evaluation of 4-(aminomethyl)-1-hydroxypyrazole analogues of muscimol as ¿-aminobutyric acidA receptor agonists

    Petersen, J. G., Bergmann, R., Møller, H. A., Jørgensen, C. G., Nielsen, Birgitte, Kehler, J., Frydenvang, Karla Andrea, Kristensen, Jesper Langgaard, Balle, T., Jensen, Anders A., Kristiansen, Uffe & Frølund, Bente, 2013, In : Journal of Medicinal Chemistry. 56, 3, p. 993-1006

    Research output: Contribution to journalJournal articleResearchpeer-review

  90. Published

    Synthesis, pharmacological and structural characterization, and thermodynamic aspects of GluA2-positive allosteric modulators with a 3,4-dihydro-2H-1,2,4-benzothiadiazine 1,1-dioxide scaffold

    Nørholm, A., Francotte, P., Olsen, L., Krintel, C., Frydenvang, Karla Andrea, Goffin, E., Challal, S., Danober, L., Botez-Pop, I., Lestage, P., Pirotte, B. & Kastrup, Jette Sandholm Jensen, 14 Nov 2013, In : Journal of Medicinal Chemistry. 56, 21, p. 8736-45 10 p.

    Research output: Contribution to journalJournal articleResearch

  91. 2014
  92. Published

    Advances towards aromatic oligoamide foldamers: synthesis and X-ray structures of dimeric arylopeptoids with conformation-directing side chains

    Hjelmgaard, T., Plesner, M., Dissing, M. M., Andersen, J. M., Frydenvang, Karla Andrea & Nielsen, John, 2014, In : European Journal of Organic Chemistry. 2014, 19, p. 3971-3975 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  93. Published
  94. Published

    Molecular recognition of two 2,4-syn-functionalized (S)-glutamate analogues by the kainate receptor GluK3 ligand-binding domain

    Venskutonyte, R., Larsen, A. P., Frydenvang, Karla Andrea, Gajhede, Michael, Gefflaut, T., Pickering, Darryl S, Bunch, Lennart & Kastrup, Jette Sandholm Jensen, 2014, In : ChemMedChem. 9, 10, p. 2254-2259 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  95. Published

    L-Asp is a useful tool in the purification of the ionotropic glutamate receptor A2 ligand-binding domain

    Krintel, C., Frydenvang, Karla Andrea, Ceravalls de Rabassa, A., Kaern, A. M., Gajhede, Michael, Pickering, Darryl S & Kastrup, Jette Sandholm Jensen, 27 Mar 2014, In : F E B S Journal. p. 2422–2430 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  96. Published

    Positive Allosteric Modulators of 2-Amino-3-(3-hydroxy-5-methylisoxazol-4-yl)propionic Acid Receptors Belonging to 4-Cyclopropyl-3,4-dihydro-2H-1,2,4-pyridothiadiazine Dioxides and Diversely Chloro-Substituted 4-Cyclopropyl-3,4-dihydro-2H-1,2,4-benzothiadiazine 1,1-Dioxides

    Francotte, P., Nørholm, A., Deva, T., Olsen, L., Frydenvang, Karla Andrea, Goffin, E., Fraikin, P., de Tullio, P., Challal, S., Thomas, J., Iop, F., Louis, C., Botez-Pop, I., Lestage, P., Danober, L., Kastrup, Jette Sandholm Jensen & Pirotte, B., 26 Nov 2014, In : Journal of Medicinal Chemistry. 57, 22, p. 9539-53 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  97. 2015
  98. Published

    Iminolactones from Schizophyllum commune

    Liu, X., Frydenvang, Karla Andrea, Liu, H., Zhai, L., Chen, M., Olsen, C. E. & Christensen, Søren Brøgger, 2015, In : Journal of Natural Products. 78, 5, p. 1165-1168 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  99. Published

    Structure-Activity Relationship Study of Ionotropic Glutamate Receptor Antagonist (2S,3R)-3-(3-Carboxyphenyl)pyrrolidine-2-carboxylic Acid

    Krogsgaard-Larsen, N., Storgaard, M., Møller, C., Demmer, C. S., Hansen, J., Han, L., Monrad, R. N., Nielsen, Birgitte, Tapken, D., Pickering, Darryl S, Kastrup, Jette Sandholm Jensen, Frydenvang, Karla Andrea & Bunch, Lennart, 2015, In : Journal of Medicinal Chemistry. 58, 15, p. 6131-50 20 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  100. Published

    Binding Mode of an α-Amino Acid-Linked Quinoxaline-2,3-dione Analogue at Glutamate Receptor Subtype GluK1

    Demmer, C. S., Møller, C., Brown, P. M. G. E., Han, L., Pickering, Darryl S, Nielsen, Birgitte, Bowie, D., Frydenvang, Karla Andrea, Kastrup, Jette Sandholm Jensen & Bunch, Lennart, 9 Apr 2015, In : A C S Chemical Neuroscience. 6, p. 845-854 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  101. Published

    A novel dualistic profile of an allosteric AMPA receptor modulator identified through studies on recombinant receptors, mouse hippocampal synapses and crystal structures

    Christiansen, G. B., Harbak, B., Hede, S. E., Gouliaev, A. H., Olsen, L., Frydenvang, Karla Andrea, Egebjerg, J., Kastrup, Jette Sandholm Jensen & Holm, M. M., 3 Dec 2015, In : Neuroscience. 310, p. 709-22 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  102. 2016
  103. Published

    Enthalpy-Entropy Compensation in the Binding of Modulators at Ionotropic Glutamate Receptor GluA2

    Krintel, C., Francotte, P., Pickering, Darryl S, Juknaite, L., Pøhlsgaaard, J., Olsen, L., Frydenvang, Karla Andrea, Goffin, E., Pirotte, B. & Kastrup, Jette Sandholm Jensen, 2016, In : Biophysical Journal. 110, 11, p. 2397-2406 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  104. Published

    Iminolactones as Tools for Inversion of the Absolute Configuration of alpha-Amino Acids and as Inhibitors of Cancer Cell Proliferation

    Jensen, C. M., Chow, H., Chen, M., Zhai, L., Frydenvang, Karla Andrea, Liu, H., Franzyk, Henrik & Christensen, Søren Brøgger, 2016, In : European Journal of Medicinal Chemistry. 114, p. 118-133 16 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  105. Published

    Structure of a High-Affinity Kainate Receptor: GluK4 Ligand-Binding Domain Crystallized with Kainate

    Kristensen, O., Kristensen, L. B., Møllerud, Stine, Frydenvang, Karla Andrea, Pickering, Darryl S & Kastrup, Jette Sandholm Jensen, 2016, In : Structure. 24, 9, p. 1582-1589 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  106. Published

    Studies on Aryl-Substituted Phenylalanines: Synthesis, Activity, and Different Binding Modes at AMPA Receptors

    Szymanska, E., Frydenvang, Karla Andrea, Pickering, Darryl S, Krintel, C., Nielsen, Birgitte, Kooshki, A., Dorvil, Linda Grønborg, Olsen, L., Kastrup, Jette Sandholm Jensen & Johansen, Tommy Nørskov, 2016, In : Journal of Medicinal Chemistry. 59, 1, p. 448-461 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  107. Published

    Tweaking subtype-selectivity and agonist efficacy at (S)-2-amino-3-(3-hydroxy-5-methyl-isoxazol-4-yl)propionic acid (AMPA) receptors in a small series of BnTetAMPA analogues

    Wang, S., Larsen, Y., Navarrete, C. V., Jensen, Anders A., Nielsen, Birgitte, Al-Musaed, A., Frydenvang, Karla Andrea, Kastrup, Jette Sandholm Jensen, Pickering, Darryl S & Clausen, Rasmus Prætorius, 2016, In : Journal of Medicinal Chemistry. 59, 5, p. 2244-2254 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  108. Published

    Synthesis and Pharmacology of Mono-, Di-, and Trialkyl-Substituted 7-Chloro-3,4-dihydro-2H-1,2,4-benzothiadiazine 1,1-Dioxides Combined with X-ray Structure Analysis to Understand the Unexpected Structure-Activity Relationship at AMPA Receptors

    Larsen, A. P., Francotte, P., Frydenvang, Karla Andrea, Tapken, D., Goffin, E., Fraikin, P., Caignard, D., Lestage, P., Danober, L., Pirotte, B. & Kastrup, Jette Sandholm Jensen, 16 Mar 2016, In : A C S Chemical Neuroscience. 7, 3, p. 378-90 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  109. 2017
  110. Published

    Design and Synthesis of a Series of L-trans-4-Substituted Prolines as Selective Antagonists for the Ionotropic Glutamate Receptors Including Functional and X-ray Crystallographic Studies of New Subtype Selective Kainic Acid Receptor Subtype 1 (GluK1) Antagonist (2S,4R)-4-(2-Carboxyphenoxy)pyrrolidine-2-carboxylic Acid

    Krogsgaard-Larsen, N., Delgar, C., Koch, K., Brown, P. M. G. E., Møller, C., Han, L., Huynh, T. H. V., Hansen, S. W., Nielsen, Birgitte, Bowie, D., Pickering, Darryl S, Kastrup, Jette Sandholm Jensen, Frydenvang, Karla Andrea & Bunch, Lennart, 2017, In : Journal of Medicinal Chemistry. 60, 1, p. 441-457 17 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  111. Published

    Structure and affinity of two bicyclic glutamate analogues at AMPA and kainate receptors

    Møllerud, Stine, Pinto, A., Marconi, L., Frydenvang, Karla Andrea, Thorsen, Thor Seneca, Laulumaa, S. K., Venskutonyte, R., Winther, N., Cunado Moral, A. M., Tamborini, L., Conti, P., Pickering, Darryl S & Kastrup, Jette Sandholm Jensen, 2017, In : A C S Chemical Neuroscience. 8, 9, p. 2056-2064 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  112. Published

    Lessons from crystal structures of kainate receptors

    Møllerud, Stine, Frydenvang, Karla Andrea, Pickering, Darryl S & Kastrup, Jette Sandholm Jensen, 1 Jan 2017, In : Neuropharmacology. 112, Part A, p. 16-28 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  113. Published

    Identification and Structure-Function Study of Positive Allosteric Modulators of Kainate Receptors

    Larsen, A. P., Fièvre, S., Frydenvang, Karla Andrea, Francotte, P., Pirotte, B., Kastrup, Jette Sandholm Jensen & Mulle, C., Jun 2017, In : Molecular Pharmacology. 91, 6, p. 576-585 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  114. Published

    Pharmacology and crystal structure of novel 2,3-quinoxalinediones at kainate receptors

    Møllerud, Stine, Pallesen, J. S., Pasini, D., Marconi, L., Han, L., Bornholt, J., Johansen, Tommy Nørskov, Kastrup, Jette Sandholm Jensen, Pickering, Darryl S & Frydenvang, Karla Andrea, Aug 2017, In : Journal of Neurochemistry. 142, S1, p. 124 1 p., MTU07-13.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  115. Published

    Metformin, an Anthropogenic Contaminant of Seidlitzia rosmarinus Collected in a Desert Region near the Gulf of Aqaba, Sinai Peninsula

    Hassan, A. R., El-Kousy, S. M., El-Toumy, S. A., Frydenvang, Karla Andrea, Tung, T. T., Olsen, J., Nielsen, John & Christensen, Søren Brøgger, 27 Oct 2017, In : Journal of Natural Products. 80, p. 2830-2834 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  116. 2018
  117. Published

    7-Phenoxy-Substituted 3,4-Dihydro-2H-1,2,4-benzothiadiazine 1,1-Dioxides as Positive Allosteric Modulators of α-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid (AMPA) Receptors with Nanomolar Potency

    Goffin, E., Drapier, T., Larsen, A. P., Geubelle, P., Ptak, C. P., Laulumaa, S., Rovinskaja, K., Gilissen, J., Tullio, P. D., Olsen, L., Frydenvang, Karla Andrea, Pirotte, B., Hanson, J., Oswald, R. E., Kastrup, Jette Sandholm Jensen & Francotte, P., Jan 2018, In : Journal of Medicinal Chemistry. 61, 1, p. 251–264

    Research output: Contribution to journalJournal articleResearchpeer-review

  118. Published

    (S)-2-Amino-3-(5-methyl-3-hydroxyisoxazol-4-yl)propanoic Acid (AMPA) and Kainate Receptor Ligands: Further Exploration of Bioisosteric Replacements, Structural and Biological Investigation.

    Brogi, S., Brindisi, M., Butini, S., Kshirsagar, G., Maramai, S., Chemi, G., Gemma, S., Campiani, G., Novellino, E., Fiorenzani, P., Pinassi, J., Aloisi, A. M., Gynther, M., Venskutonyte, R., Han, L., Frydenvang, Karla Andrea, Kastrup, Jette Sandholm Jensen & Pickering, Darryl S, 8 Mar 2018, In : Journal of Medicinal Chemistry. 61, 5, p. 2124-2130 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  119. 2019
  120. Published
  121. Published

    Structural analysis of Cytochrome P450 BM3 mutant M11 in complex with dithiothreitol

    Frydenvang, Karla Andrea, Verkade-Vreeker, M. C. A., Dohmen, F., Commandeur, J. N. M., Rafiq, Maria, Mirza, Osman Asghar, Jørgensen, Flemming Steen & Geerke, D. P., 2019, In : PLoS ONE. 14, 5, 15 p., e0217292.

    Research output: Contribution to journalJournal articleResearchpeer-review

  122. Published

    Crystal Structures of Potent Dimeric Positive Allosteric Modulators at the Ligand-Binding Domain of the GluA2 Receptor

    Laulumaa, S., Hansen, K. V., Masternak, M., Drapier, T., Francotte, P., Pirotte, B., Frydenvang, Karla Andrea & Kastrup, Jette Sandholm Jensen, 14 Mar 2019, In : ACS Medicinal Chemistry Letters. 10, 3, p. 243-247 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  123. Published

    N1-Substituted Quinoxaline-2,3-diones as Kainate Receptor Antagonists: X-ray Crystallography, Structure-Affinity Relationships and in vitro Pharmacology

    Pallesen, J. S., Møllerud, Stine, Frydenvang, Karla Andrea, Pickering, Darryl S, Bornholt, J., Nielsen, Birgitte, Pasini, D., Han, L., Marconi, L., Kastrup, Jette Sandholm Jensen & Johansen, Tommy Nørskov, 20 Mar 2019, In : A C S Chemical Neuroscience. 10, p. 1841-1853 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  124. Published

    Functionalized Helical beta-Peptoids

    Wellhöfer, Isabelle, Frydenvang, Karla Andrea, Kotesova, S., Christiansen, A. M., Laursen, J. S. & Olsen, Christian Adam, 5 Apr 2019, In : Journal of Organic Chemistry. 84, 7, p. 3762-3779

    Research output: Contribution to journalJournal articleResearchpeer-review

  125. Published

    Nanoscale Mobility of the Apo State and TARP Stoichiometry Dictate the Gating Behavior of Alternatively Spliced AMPA Receptors

    Dawe, G. B., Kadir, M. F., Venskutonyte, R., Perozzo, A. M., Yan, Y., Alexander, R. P. D., Navarrete, C., Santander, E. A., Arsenault, M., Fuentes, C., Aurousseau, M. R. P., Frydenvang, Karla Andrea, Barrera, N. P., Kastrup, Jette Sandholm Jensen, Edwardson, J. M. & Bowie, D., 5 Jun 2019, In : Neuron. 102, 5, p. 976-+

    Research output: Contribution to journalJournal articleResearchpeer-review

  126. Published

    Design and Synthesis of 2,3-trans-Proline Analogs as Ligands for the Ionotropic Glutamate Receptors and the Excitatory Amino Acid Transporters

    Poulie, Christian Bernard Matthijs, Alcaide Lopez, A., Krell-Jørgensen, M. P., Larsen, Y., Astier, E., Bjørn-Yoshimoto, Walden, Yi, F., Syrenne, J. T., Storgaard, M., Nielsen, Birgitte, Frydenvang, Karla Andrea, Jensen, Anders A., Hansen, K. B., Pickering, Darryl S & Bunch, Lennart, 19 Jun 2019, In : A C S Chemical Neuroscience. 10, 6, p. 2989-3007 19 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  127. Published

    Five-membered N-heterocyclic Scaffolds as Novel Amino Bioisosteres at gamma-Aminobutyric Acid (GABA) Type A Receptors and GABA Transporters

    Giraudo, A., Krall, J., Bavo, F., Nielsen, Birgitte, Kongstad, Kenneth Thermann, Rolando, B., De Blasio, R., Gloriam, David E., Löffler, R., Thiesen, Louise, Harpsøe, Kasper, Frydenvang, Karla Andrea, Boschi, D., Wellendorph, Petrine, Lolli, M. L., Jensen, Anders A. & Frølund, Bente, 27 Jun 2019, In : Journal of Medicinal Chemistry. 62, 12, p. 5797-5809

    Research output: Contribution to journalJournal articleResearchpeer-review

ID: 1305625