Karla Andrea Frydenvang

Karla Andrea Frydenvang

Associate Professor

Introductory remarks on publicationslist

See Homepage for complete list of publications (incl. all publications from before 2007)
  1. Published

    Structural characterisation and dehydration behaviour of siramesine hydrochloride. / Zimmermann, Anne; Tian, Fang; Lopez de Diego, Heidi; Frydenvang, Karla Andrea; Rantanen, Jukka Tapio; Elema, Michiel Ringkjøbing; Hovgaard, Lars.

    In: Journal of Pharmaceutical Sciences, Vol. 98, No. 10, 2009, p. 3596-3607.

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Published

    Functionalized Helical beta-Peptoids. / Wellhofer, Isabelle; Frydenvang, Karla; Kotesova, Simona; Christiansen, Andreas M.; Laursen, Jonas Striegler; Olsen, Christian A.

    In: Journal of Organic Chemistry, Vol. 84, No. 7, 05.04.2019, p. 3762-3779.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Tweaking subtype-selectivity and agonist efficacy at (S)-2-amino-3-(3-hydroxy-5-methyl-isoxazol-4-yl)propionic acid (AMPA) receptors in a small series of BnTetAMPA analogues. / Wang, Shuang-Yan; Larsen, Younes; Navarrete, Cristina V.; Jensen, Anders A.; Nielsen, Birgitte; Al-Musaed, Ali; Frydenvang, Karla; Kastrup, Jette Sandholm; Pickering, Darryl S; Clausen, Rasmus Prætorius.

    In: Journal of Medicinal Chemistry, Vol. 59, No. 5, 2016, p. 2244-2254.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    A tetrazolyl-substituted subtype-selective AMPA receptor agonist. / Vogensen, Stine Byskov; Frydenvang, Karla Andrea; Greenwood, Jeremy R.; Postorino, Giovanna; Nielsen, Birgitte; Pickering, Darryl Scott; Ebert, Bjarke; Bølcho, Ulrik; Egebjerg, Jan; Gajhede, Michael; Kastrup, Jette Sandholm Jensen; Johansen, Tommy Nørskov; Clausen, Rasmus Prætorius; Krogsgaard-Larsen, Povl.

    In: Journal of Medicinal Chemistry, Vol. 50, No. 10, 2007, p. 2408-2414.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Resolution, configurational assignment, and enantiopharmacology of 2-amino-3-[3-hydroxy-5-(2-methyl-2H- tetrazol-5-yl)isoxazol-4-yl]propionic acid, a potent GluR3- and GluR4-preferring AMPA receptor agonist. / Vogensen, S B; Jensen, H S; Stensbøl, T B; Frydenvang, Karla Andrea; Bang-Andersen, B; Johansen, T N; Egebjerg, J; Krogsgaard-Larsen, P.

    In: Chirality, Vol. 12, No. 10, 2000, p. 705-13.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Binding site and interlobe interactions of the ionotropic glutamate receptor GluK3 ligand binding domain revealed by high resolution crystal structure in complex with (S)-glutamate. / Venskutonyte, Raminta; Frydenvang, Karla; Gajhede, Michael; Bunch, Lennart; Pickering, Darryl S; Kastrup, Jette Sandholm.

    In: Journal of Structural Biology, Vol. 176, No. 3, 12.2011, p. 307-314.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Kainate induces various domain closures in AMPA and kainate receptors. / Venskutonyte, Raminta; Frydenvang, Karla; Hald, Helle; Rabassa, Anna Ceravalls de; Gajhede, Michael; Ahring, Philip K.; Kastrup, Jette Sandholm.

    In: Neurochemistry International, Vol. 61, No. 4, 09.2012, p. 536-545.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Selective kainate receptor (GluK1) ligands structurally based upon1H-Cyclopentapyrimidin-2,4(1H,3H)-dione: synthesis, molecular modeling, and pharmacological and biostructural characterization. / Venskutonyte, Raminta; Butini, Stefania; Coccone, Salvatore Sanna; Gemma, Sandra; Brindisi, Margherita; Kumar, Vinod; Guarino, Ergeria; Maramai, Samuele; Valenti, Salvatore; Amir, Ahmad; Valades, Elena Anton; Frydenvang, Karla Andrea; Kastrup, Jette Sandholm Jensen; Novellino, Ettore; Campiani, Giuseppe; Pickering, Darryl S.

    In: Journal of Medicinal Chemistry, Vol. 54, No. 13, 14.07.2011, p. 4793-4805.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Molecular recognition of two 2,4-syn-functionalized (S)-glutamate analogues by the kainate receptor GluK3 ligand-binding domain. / Venskutonyte, Raminta; Larsen, Anja Probst; Frydenvang, Karla Andrea; Gajhede, Michael; Gefflaut, Thierry; Pickering, Darryl S; Bunch, Lennart; Kastrup, Jette Sandholm Jensen.

    In: ChemMedChem, Vol. 9, No. 10, 2014, p. 2254-2259.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Structural and pharmacological characterization of phenylalanine-based AMPA receptor antagonists at kainate receptors. / Venskutonyte, Raminta; Frydenvang, Karla; Valadés, Elena Antón; Szymanska, Ewa Monika; Johansen, Tommy N; Kastrup, Jette S; Pickering, Darryl S.

    In: ChemMedChem, Vol. 7, No. 10, 10.2012, p. 1793-1798.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Studies on Aryl-Substituted Phenylalanines: Synthesis, Activity, and Different Binding Modes at AMPA Receptors. / Szymanska, Ewa; Frydenvang, Karla Andrea; Pickering, Darryl S; Krintel, Christian; Nielsen, Birgitte; Kooshki, Ayesheh; Zachariassen, Linda Grønborg; Olsen, Lars; Kastrup, Jette Sandholm Jensen; Johansen, Tommy Nørskov.

    In: Journal of Medicinal Chemistry, Vol. 59, No. 1, 2016, p. 448-461.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    A new phenylalanine derivative acts as an antagonist at the AMPA receptor GluA2 and introduces partial domain closure : Synthesis, resolution, pharmacology, and crystal structure. / Szymanska, Ewa; Frydenvang, Karla; Contreras-Sanz, Alberto; Pickering, Darryl S; Frola, Elena; Serafimoska, Zorica; Nielsen, Birgitte; Kastrup, Jette Sandholm; Johansen, Tommy Nørskov.

    In: Journal of Medicinal Chemistry, Vol. 54, No. 20, 04.10.2011, p. 7289-7298.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Stereochemistry and molecular pharmacology of (S)-thio-ATPA, a new potent and selective GluR5 agonist. / Stensbøl, T B; Jensen, H S; Nielsen, B; Johansen, T N; Egebjerg, J; Frydenvang, Karla Andrea; Krogsgaard-Larsen, P.

    In: European Journal of Pharmacology, Vol. 411, No. 3, 2001, p. 245-53.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Synthesis and characterization of an epimer of tacrolimus, an immunosuppressive drug. / Skytte, Dorthe Mondrup; Frydenvang, Karla Andrea; Hansen, Liselotte; Nielsen, Peter G; Jaroszewski, Jerzy W.

    In: Journal of Natural Products, Vol. 73, No. 4, 18.02.2010, p. 776-779.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Some transformations of tacrolimus, an immunosuppressive drug. / Skytte, Dorthe Mondrup; Jaroszewski, Jerzy W.; Johansen, Kenneth; Hansen, Steen Honore'; Hansen, Liselotte; G. Nielsen, Peter; Frydenvang, Karla Andrea.

    In: European Journal of Pharmaceutical Sciences, Vol. 48, No. 3, 2013, p. 514-522.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    Sesquiterpenes from Thapsia nitida var. meridionalis and Thapsia nitida var. nitida. / Rubal, Juan J; Guerra, Francisco M; Moreno-Dorado, F Javier; Jorge, Zacarías D; Massanet, Guillermo M; Søhoel, Helmer; Smitt, Ulla W; Frydenvang, Karla Andrea; Christensen, S Brøgger; Nielsen, Charlotte; Eriksson, Margit.

    In: Journal of Natural Products, Vol. 69, No. 11, 2006, p. 1566-71.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Lessons from more than 80 structures of the GluA2 ligand-binding domain in complex with agonists, antagonists and allosteric modulators. / Pøhlsgaard, Jacob; Frydenvang, Karla Andrea; Madsen, Ulf; Kastrup, Jette Sandholm.

    In: Neuropharmacology, Vol. 60, No. 1, 01.01.2011, p. 135-150.

    Research output: Contribution to journalReviewResearchpeer-review

  18. Published

    Design and Synthesis of 2,3-trans-Proline Analogs as Ligands for the Ionotropic Glutamate Receptors and the Excitatory Amino Acid Transporters. / Poulie, Christian Bernard Matthijs; Alcaide Lopez, Anna; Krell-Jørgensen, Mikkel Poul; Larsen, Younes; Astier, Eloi; Bjørn-Yoshimoto, Walden E.; Yi, Feng; Syrenne, Jed T; Storgaard, Morten; Nielsen, Birgitte; Frydenvang, Karla Andrea; Jensen, Anders A.; Hansen, Kasper B; Pickering, Darryl S; Bunch, Lennart.

    In: A C S Chemical Neuroscience, Vol. 10, No. 6, 19.06.2019, p. 2989-3007.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Synthesis and biological evaluation of 4-(aminomethyl)-1-hydroxypyrazole analogues of muscimol as ¿-aminobutyric acidA receptor agonists. / Petersen, Jette Gellert; Bergmann, Rikke; Møller, Henriette A.; Jørgensen, Charlotte Grube; Nielsen, Birgitte; Kehler, Jan; Frydenvang, Karla ; Kristensen, Jesper; Balle, Thomas; Jensen, Anders A.; Kristiansen, Uffe; Frølund, Bente.

    In: Journal of Medicinal Chemistry, Vol. 56, No. 3, 2013, p. 993-1006.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Synthesis and muscarinic receptor pharmacology of a series of 4,5,6,7-tetrahydroisothiazolo[4,5-c]pyridine bioisosteres of arecoline. / Pedersen, H; Bräuner-Osborne, H; Ball, R G; Frydenvang, Karla Andrea; Meier, E; Bøgesø, K P; Krogsgaard-Larsen, P.

    In: Bioorganic & Medicinal Chemistry, Vol. 7, No. 5, 1999, p. 795-809.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    Aqueous solubility study of salts of benzylamine derivatives and p-substituted benzoic acid derivatives using X-ray crystallographic analysis. / Parshad, Henrik; Frydenvang, Karla Andrea; Liljefors, Tommy; Sorensen, Henning Osholm; Larsen, Claus.

    In: International Journal of Pharmaceutics, Vol. 269, No. 1, 2004, p. 157-68.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Assessment of drug salt release from solutions, suspensions and in situ suspensions using a rotating dialysis cell. / Parshad, Henrik; Frydenvang, Karla; Liljefors, Tommy; Cornett, Claus; Larsen, Claus.

    In: European Journal of Pharmaceutical Sciences, Vol. 19, No. 4, 2003, p. 263-272.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Correlation of aqueous solubility of salts of benzylamine with experimentally and theoretically derived parameters. A multivariate data analysis approach. / Parshad, Henrik; Frydenvang, Karla Andrea; Liljefors, Tommy; Larsen, Claus Selch.

    In: International Journal of Pharmaceutics, Vol. 237, No. 1-2, 2002, p. 193-207.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    N1-Substituted Quinoxaline-2,3-diones as Kainate Receptor Antagonists: X-ray Crystallography, Structure-Affinity Relationships and in vitro Pharmacology. / Pallesen, Jakob Staun; Møllerud, Stine; Frydenvang, Karla Andrea; Pickering, Darryl S; Bornholt, Jan; Nielsen, Birgitte; Pasini, Diletta; Han, Liwei; Marconi, Laura; Kastrup, Jette Sandholm Jensen; Johansen, Tommy Nørskov.

    In: A C S Chemical Neuroscience, Vol. 10, 20.03.2019, p. 1841-1853.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Andrastin A and barceloneic acid metabolites, protein farnesyl transferase inhibitors from Penicillium albocoremium: chemotaxonomic significance and pathological implications. / Overy, David P.; Larsen, Thomas O.; Dalsgaard, Petur Weihe; Frydenvang, Karla Andrea; Phipps, Richard; Munro, Murray H. G.; Christophersen, Carsten.

    In: Mycological Research, No. 109, 2005, p. 1243-1249.

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    UV-guided screening of benzodiazepine producing species in Penicillium. / Ostenfeld Larsen T, ; Frydenvang, Karla Andrea; Christian Frisvad J.

    In: Biochemical Systematics and Ecology, Vol. 28, No. 9, 2000, p. 881-886.

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Published

    Antiprotozoal properties of 16,17-dihydrobrachycalyxolide from Vernonia brachycalyx. / Oketch-Rabah, H A; Brøgger Christensen, S; Frydenvang, K; Dossaji, S F; Theander, T G; Cornett, C; Watkins, W M; Kharazmi, A; Lemmich, E.

    In: Planta Medica, Vol. 64, No. 6, 1998, p. 559-62.

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. Published

    Antiprotozoal compounds from Asparagus africanus. / Oketch-Rabah, H A; Dossaji, S F; Christensen, S B; Frydenvang, K; Lemmich, E; Cornett, C; Olsen, C E; Chen, M; Kharazmi, A; Theander, T.

    In: Journal of Natural Products, Vol. 60, No. 10, 1997, p. 1017-22.

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. Published

    Synthesis, pharmacological and structural characterization, and thermodynamic aspects of GluA2-positive allosteric modulators with a 3,4-dihydro-2H-1,2,4-benzothiadiazine 1,1-dioxide scaffold. / Nørholm, Ann-Beth; Francotte, Pierre; Olsen, Lars; Krintel, Christian; Frydenvang, Karla; Goffin, Eric; Challal, Sylvie; Danober, Laurence; Botez-Pop, Iuliana; Lestage, Pierre; Pirotte, Bernard; Kastrup, Jette S.

    In: Journal of Medicinal Chemistry, Vol. 56, No. 21, 14.11.2013, p. 8736-45.

    Research output: Contribution to journalJournal articleResearch

  30. Published

    Assessment of the combined approach of N-alkylation and salt formation to enhance aqueous solubility of tertiary amines using bupivacaine as a model drug. / Nielsen, Anders Bach; Frydenvang, Karla Andrea; Liljefors, Tommy; Buur, Anders; Larsen, Claus.

    In: European Journal of Pharmaceutical Sciences, Vol. 24, No. 1, 2005, p. 85-93.

    Research output: Contribution to journalJournal articleResearchpeer-review

  31. Published

    Lessons from crystal structures of kainate receptors. / Møllerud, Stine; Frydenvang, Karla Andrea; Pickering, Darryl S; Kastrup, Jette Sandholm Jensen.

    In: Neuropharmacology, Vol. 112, No. Part A, 01.01.2017, p. 16-28.

    Research output: Contribution to journalJournal articleResearchpeer-review

  32. Published
  33. Published

    Structure and affinity of two bicyclic glutamate analogues at AMPA and kainate receptors. / Møllerud, Stine; Pinto, Andrea; Marconi, Laura; Frydenvang, Karla Andrea; Thorsen, Thor Seneca; Laulumaa, Saara Kaisa; Venskutonyte, Raminta; Winther, Nikolaj; Cunado Moral, Ana Maria; Tamborini, Lucia; Conti, Paola; Pickering, Darryl S; Kastrup, Jette Sandholm Jensen.

    In: A C S Chemical Neuroscience, Vol. 8, No. 9, 2017, p. 2056-2064.

    Research output: Contribution to journalJournal articleResearchpeer-review

  34. Published

    Pharmacology and crystal structure of novel 2,3-quinoxalinediones at kainate receptors. / Møllerud, Stine; Pallesen, Jakob Staun; Pasini, Diletta; Marconi, Laura; Han, Liwei; Bornholt, Jan; Johansen, Tommy Nørskov; Kastrup, Jette Sandholm ; Pickering, Darryl S; Frydenvang, Karla Andrea.

    In: Journal of Neurochemistry, Vol. 142, No. S1, MTU07-13, 08.2017, p. 124.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  35. Published

    Synthesis and pharmacology of 3-isoxazolol amino acids as selective antagonists at group I metabotropic glutamic acid receptors. / Madsen, U; Bräuner-Osborne, H; Frydenvang, Karla Andrea; Hvene, L; Johansen, T N; Nielsen, B; Sánchez, C; Stensbøl, T B; Bischoff, F; Krogsgaard-Larsen, P.

    In: Journal of Medicinal Chemistry, Vol. 44, No. 7, 2001, p. 1051-9.

    Research output: Contribution to journalJournal articleResearchpeer-review

  36. Published

    N-methyl-D-aspartic acid receptor agonists : resolution, absolute stereochemistry, and pharmacology of the enantiomers of 2-amino-2-(3-hydroxy-5-methyl-4-isoxazolyl)acetic acid. / Madsen, U; Frydenvang, Karla Andrea; Ebert, B; Johansen, T N; Brehm, L; Krogsgaard-Larsen, P.

    In: Journal of Medicinal Chemistry, Vol. 39, No. 1, 1996, p. 183-90.

    Research output: Contribution to journalJournal articleResearchpeer-review

  37. Published

    Iminolactones from Schizophyllum commune. / Liu, Xuemei; Frydenvang, Karla Andrea; Liu, Huizhen; Zhai, Lin; Chen, Ming; Olsen, Carl Erik; Christensen, Søren Brøgger.

    In: Journal of Natural Products, Vol. 78, No. 5, 2015, p. 1165-1168.

    Research output: Contribution to journalJournal articleResearchpeer-review

  38. Published

    Crystal Structures of Potent Dimeric Positive Allosteric Modulators at the Ligand-Binding Domain of the GluA2 Receptor. / Laulumaa, Saara; Hansen, Kathrine Voigt; Masternak, Magdalena; Drapier, Thomas; Francotte, Pierre; Pirotte, Bernard; Frydenvang, Karla; Kastrup, Jette Sandholm.

    In: ACS Medicinal Chemistry Letters, Vol. 10, No. 3, 14.03.2019, p. 243-247.

    Research output: Contribution to journalJournal articleResearchpeer-review

  39. Published

    UV-Guided isolation of alantrypinone, a novel Penicillium alkaloid. / Larsen, T O; Frydenvang, Karla Andrea; Frisvad, Jens Christian; Christophersen, C.

    In: Journal of Natural Products, Vol. 61, No. 9, 1998, p. 1154-7.

    Research output: Contribution to journalJournal articleResearchpeer-review

  40. Published

    Synthesis and Pharmacology of Mono-, Di-, and Trialkyl-Substituted 7-Chloro-3,4-dihydro-2H-1,2,4-benzothiadiazine 1,1-Dioxides Combined with X-ray Structure Analysis to Understand the Unexpected Structure-Activity Relationship at AMPA Receptors. / Larsen, Anja Probst; Francotte, Pierre; Frydenvang, Karla; Tapken, Daniel; Goffin, Eric; Fraikin, Pierre; Caignard, Daniel-Henri; Lestage, Pierre; Danober, Laurence; Pirotte, Bernard; Kastrup, Jette Sandholm.

    In: A C S Chemical Neuroscience, Vol. 7, No. 3, 16.03.2016, p. 378-90.

    Research output: Contribution to journalJournal articleResearchpeer-review

  41. Published

    Identification and Structure-Function Study of Positive Allosteric Modulators of Kainate Receptors. / Larsen, Anja Probst; Fièvre, Sabine; Frydenvang, Karla; Francotte, Pierre; Pirotte, Bernard; Kastrup, Jette Sandholm; Mulle, Christophe.

    In: Molecular Pharmacology, Vol. 91, No. 6, 06.2017, p. 576-585.

    Research output: Contribution to journalJournal articleResearchpeer-review

  42. Published

    GABA uptake inhibitors. Design, molecular pharmacology and therapeutic aspects. / Krogsgaard-Larsen, P; Frølund, B; Frydenvang, Karla Andrea.

    In: Current Pharmaceutical Design, Vol. 6, No. 12, 2000, p. 1193-209.

    Research output: Contribution to journalJournal articleResearchpeer-review

  43. Published

    Design and Synthesis of a Series of L-trans-4-Substituted Prolines as Selective Antagonists for the Ionotropic Glutamate Receptors Including Functional and X-ray Crystallographic Studies of New Subtype Selective Kainic Acid Receptor Subtype 1 (GluK1) Antagonist (2S,4R)-4-(2-Carboxyphenoxy)pyrrolidine-2-carboxylic Acid. / Krogsgaard-Larsen, Niels; Delgar, Claudia; Koch, Karina; Brown, Patricia M G E; Møller, Charlotte; Han, Liwei; Huynh, Tri Hien Viet; Hansen, Stinne Wessel; Nielsen, Birgitte; Bowie, Derek; Pickering, Darryl S; Kastrup, Jette Sandholm Jensen; Frydenvang, Karla Andrea; Bunch, Lennart.

    In: Journal of Medicinal Chemistry, Vol. 60, No. 1, 2017, p. 441-457.

    Research output: Contribution to journalJournal articleResearchpeer-review

  44. Published

    Syntheses of aza-analogous iso-ergoline scaffolds using carbene mediated C-H insertion. / Krogsgaard-Larsen, Niels; Begtrup, Mikael; Frydenvang, Karla Andrea; Kehler, Jan .

    In: Tetrahedron, Vol. 66, No. 47, 20.11.2010, p. 9297-9303.

    Research output: Contribution to journalJournal articleResearchpeer-review

  45. Published

    Structure-Activity Relationship Study of Ionotropic Glutamate Receptor Antagonist (2S,3R)-3-(3-Carboxyphenyl)pyrrolidine-2-carboxylic Acid. / Krogsgaard-Larsen, Niels; Storgaard, Morten; Møller, Charlotte; Demmer, Charles S; Hansen, Jeanette; Han, Liwei; Monrad, Rune N; Nielsen, Birgitte; Tapken, Daniel; Pickering, Darryl S; Kastrup, Jette S; Frydenvang, Karla; Bunch, Lennart.

    In: Journal of Medicinal Chemistry, Vol. 58, No. 15, 2015, p. 6131-50.

    Research output: Contribution to journalJournal articleResearchpeer-review

  46. Published

    Structure of a High-Affinity Kainate Receptor: GluK4 Ligand-Binding Domain Crystallized with Kainate. / Kristensen, Ole; Kristensen, Lise Baadsgaard; Møllerud, Stine; Frydenvang, Karla Andrea; Pickering, Darryl S; Kastrup, Jette Sandholm Jensen.

    In: Structure, Vol. 24, No. 9, 2016, p. 1582-1589.

    Research output: Contribution to journalJournal articleResearchpeer-review

  47. Published

    L-Asp is a useful tool in the purification of the ionotropic glutamate receptor A2 ligand-binding domain. / Krintel, Christian; Frydenvang, Karla; Ceravalls de Rabassa, Anna; Kaern, Anne Mette; Gajhede, Michael; Pickering, Darryl S; Kastrup, Jette S.

    In: F E B S Journal, 27.03.2014, p. 2422–2430.

    Research output: Contribution to journalJournal articleResearchpeer-review

  48. Published

    Enthalpy-Entropy Compensation in the Binding of Modulators at Ionotropic Glutamate Receptor GluA2. / Krintel, Christian; Francotte, Pierre; Pickering, Darryl S; Juknaite, Lina; Pøhlsgaaard, Jakob; Olsen, Lars; Frydenvang, Karla Andrea; Goffin, Eric; Pirotte, Bernard; Kastrup, Jette Sandholm Jensen.

    In: Biophysical Journal, Vol. 110, No. 11, 2016, p. 2397-2406.

    Research output: Contribution to journalJournal articleResearchpeer-review

  49. Published

    Structural analysis of the positive AMPA receptor modulators CX516 and Me-CX516 in complex with the GluA2 ligand-binding domain. / Krintel, Christian; Harpsøe, Kasper; Zachariassen, Linda G; Peters, Dan; Frydenvang, Karla; Pickering, Darryl S; Gajhede, Michael; Kastrup, Jette S.

    In: Acta crystallographica. Section D, Biological crystallography, Vol. 69, No. Pt 9, 09.2013, p. 1645-52.

    Research output: Contribution to journalJournal articleResearchpeer-review

  50. Published

    Thermodynamics and structural analysis of positive allosteric modulation of the ionotropic glutamate receptor GluA2. / Krintel, Christian; Frydenvang, Karla; Olsen, Lars; Kristensen, Maria T; de Barrios, Oriol; Naur, Peter; Francotte, Pierre; Pirotte, Bernard; Gajhede, Michael; Kastrup, Jette Sandholm.

    In: Biochemical Journal, Vol. 441, No. 1, 01.01.2012, p. 173-178.

    Research output: Contribution to journalJournal articleResearchpeer-review

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