Karla Andrea Frydenvang
Karla Andrea Frydenvang

Associate Professor

Introductory remarks on publicationslist

See Homepage for complete list of publications (incl. all publications from before 2007)
  1. Published

    Unprecedented migration of N-alkoxycarbonyl groups in protected pyroglutaminol

    Bunch, Lennart, Norrby, P., Frydenvang, Karla Andrea, Krogsgaard-Larsen, Povl & Madsen, Ulf, 2001, In : Organic Letters. 3, 3, p. 433-5 3 p.

    Research output: Contribution to journalJournal article

  2. Published

    UV-guided screening of benzodiazepine producing species in Penicillium

    Ostenfeld Larsen T, Frydenvang, Karla Andrea & Christian Frisvad J, 2000, In : Biochemical Systematics and Ecology. 28, 9, p. 881-886 6 p.

    Research output: Contribution to journalJournal article

  3. Published

    UV-Guided isolation of alantrypinone, a novel Penicillium alkaloid

    Larsen, T. O., Frydenvang, Karla Andrea, Frisvad, J. C. & Christophersen, C., 1998, In : Journal of Natural Products. 61, 9, p. 1154-7 4 p.

    Research output: Contribution to journalJournal article

  4. Published
  5. Published

    Thermodynamics and structural analysis of positive allosteric modulation of the ionotropic glutamate receptor GluA2

    Krintel, C., Frydenvang, Karla Andrea, Olsen, L., Kristensen, M. T., de Barrios, O., Naur, P., Francotte, P., Pirotte, B., Gajhede, Michael & Kastrup, Jette Sandholm Jensen, 1 Jan 2012, In : Biochemical Journal. 441, 1, p. 173-178

    Research output: Contribution to journalJournal article

  6. Published

    Synthesis, pharmacological and structural characterization, and thermodynamic aspects of GluA2-positive allosteric modulators with a 3,4-dihydro-2H-1,2,4-benzothiadiazine 1,1-dioxide scaffold

    Nørholm, A., Francotte, P., Olsen, L., Krintel, C., Frydenvang, Karla Andrea, Goffin, E., Challal, S., Danober, L., Botez-Pop, I., Lestage, P., Pirotte, B. & Kastrup, Jette Sandholm Jensen, 14 Nov 2013, In : Journal of Medicinal Chemistry. 56, 21, p. 8736-45 10 p.

    Research output: Contribution to journalJournal article

  7. Published

    Synthesis and structure-activity studies on acidic amino acids and related diacids as NMDA receptor ligands

    Johansen, Tommy Nørskov, Frydenvang, Karla Andrea, Ebert, B., Krogsgaard-Larsen, Povl & Madsen, Ulf, 1994, In : Journal of Medicinal Chemistry. 37, 20, p. 3252-62 11 p.

    Research output: Contribution to journalJournal article

  8. Published

    Synthesis and pharmacology of 3-isoxazolol amino acids as selective antagonists at group I metabotropic glutamic acid receptors

    Madsen, Ulf, Bräuner-Osborne, Hans, Frydenvang, Karla Andrea, Hvene, L., Johansen, Tommy Nørskov, Nielsen, Birgitte, Sánchez, C., Stensbøl, T. B., Bischoff, F. & Krogsgaard-Larsen, Povl, 2001, In : Journal of Medicinal Chemistry. 44, 7, p. 1051-9 9 p.

    Research output: Contribution to journalJournal article

  9. Published

    Synthesis and pharmacological evaluation of novel conformationally constrained homologues of glutamic acid

    Conti, P., Caligiuri, A., Pinto, A., Roda, G., Tamborini, L., Nielsen, Birgitte, Madsen, Ulf, Frydenvang, Karla Andrea, Colombo, A. & De Micheli, C., 2007, In : European Journal of Medicinal Chemistry. 42, 8, p. 1059-1068

    Research output: Contribution to journalJournal article

  10. Published

    Synthesis and muscarinic receptor pharmacology of a series of 4,5,6,7-tetrahydroisothiazolo[4,5-c]pyridine bioisosteres of arecoline

    Pedersen, H., Bräuner-Osborne, Hans, Ball, R. G., Frydenvang, Karla Andrea, Meier, E., Bøgesø, K. P. & Krogsgaard-Larsen, Povl, 1999, In : Bioorganic & Medicinal Chemistry. 7, 5, p. 795-809 15 p.

    Research output: Contribution to journalJournal article

  11. Published

    Synthesis and characterization of an epimer of tacrolimus, an immunosuppressive drug

    Skytte, D. M., Frydenvang, Karla Andrea, Hansen, L., Nielsen, P. G. & Jaroszewski, J. W., 18 Feb 2010, In : Journal of Natural Products. 73, 4, p. 776-779

    Research output: Contribution to journalJournal article

  12. Published

    Synthesis and biological evaluation of 4-(aminomethyl)-1-hydroxypyrazole analogues of muscimol as ¿-aminobutyric acidA receptor agonists

    Petersen, J. G., Bergmann, R., Møller, H. A., Jørgensen, C. G., Nielsen, Birgitte, Kehler, J., Frydenvang, Karla Andrea, Kristensen, Jesper Langgaard, Balle, T., Jensen, Anders A., Kristiansen, Uffe & Frølund, Bente, 2013, In : Journal of Medicinal Chemistry. 56, 3, p. 993-1006

    Research output: Contribution to journalJournal article

  13. Published

    Synthesis and antitumor effect in vitro and in vivo of substituted 1,3-dihydroindole-2-ones

    Christensen, M. K., Erichsen, K. D., Trojel-Hansen, C., Tjørnelund, J., Nielsen, S. J., Frydenvang, Karla Andrea, Johansen, Tommy Nørskov, Nielsen, Birgitte, Sehested, M., Jensen, P. B., Ikaunieks, M., Zaichenko, A., Loza, E., Kalvinsh, I. & Björkling, Fredrik, 14 Oct 2010, In : Journal of Medicinal Chemistry. 53, 19, p. 7140-7145 6 p.

    Research output: Contribution to journalJournal article

  14. Published

    Synthesis and Pharmacology of Mono-, Di-, and Trialkyl-Substituted 7-Chloro-3,4-dihydro-2H-1,2,4-benzothiadiazine 1,1-Dioxides Combined with X-ray Structure Analysis to Understand the Unexpected Structure-Activity Relationship at AMPA Receptors

    Larsen, A. P., Francotte, P., Frydenvang, Karla Andrea, Tapken, D., Goffin, E., Fraikin, P., Caignard, D., Lestage, P., Danober, L., Pirotte, B. & Kastrup, Jette Sandholm Jensen, 16 Mar 2016, In : A C S Chemical Neuroscience. 7, 3, p. 378-90 13 p.

    Research output: Contribution to journalJournal article

  15. Published

    Syntheses of aza-analogous iso-ergoline scaffolds using carbene mediated C-H insertion

    Krogsgaard-Larsen, N., Begtrup, M., Frydenvang, Karla Andrea & Kehler, J., 20 Nov 2010, In : Tetrahedron. 66, 47, p. 9297-9303

    Research output: Contribution to journalJournal article

  16. Published

    Studies on an (S)-2-amino-3-(3-hydroxy-5-methyl-4-isoxazolyl)propionic acid (AMPA) receptor antagonist IKM-159: asymmetric synthesis, neuroactivity, and structural characterization

    Juknaite, L., Sugamata, Y., Tokiwa, K., Ishikawa, Y., Takamizawa, S., Eng, A., Sakai, R., Pickering, Darryl S, Frydenvang, Karla Andrea, Swanson, G. T., Kastrup, Jette Sandholm Jensen & Oikawa, M., 2013, In : Journal of Medicinal Chemistry. 56, 6, p. 2283-2293

    Research output: Contribution to journalJournal article

  17. Published

    Studies on Aryl-Substituted Phenylalanines: Synthesis, Activity, and Different Binding Modes at AMPA Receptors

    Szymanska, E., Frydenvang, Karla Andrea, Pickering, Darryl S, Krintel, C., Nielsen, Birgitte, Kooshki, A., Dorvil, Linda Grønborg, Olsen, L., Kastrup, Jette Sandholm Jensen & Johansen, Tommy Nørskov, 2016, In : Journal of Medicinal Chemistry. 59, 1, p. 448-461 14 p.

    Research output: Contribution to journalJournal article

  18. Published

    Structures of acetylcholine picrate and methoxycarbonylcholine picrate hemihydrate

    Frydenvang, Karla Andrea, Grønborg, L. & Jensen, B., 1988, In : Acta Crystallographica. Section C: Crystal Structure Communications. 44, Pt 5, p. 841-5 5 p.

    Research output: Contribution to journalJournal article

  19. Published

    Structure-activity relationships of a small-molecule inhibitor of the PDZ domain of PICK1

    Bach, Anders, Stuhr-Hansen, N., Thorsen, Thor Seneca, Bork, N., Moreira, I. S., Frydenvang, Karla Andrea, Padrah, S., Christensen, Søren Brøgger, Madsen, Kenneth Lindegaard, Weinstein, H., Gether, Ulrik & Strømgaard, Kristian, 2010, In : Organic & Biomolecular Chemistry. 8, 19, p. 4281-4288 8 p.

    Research output: Contribution to journalJournal article

  20. Published

    Structure-activity relationship study of first selective inhibitor of excitatory amino acid transporter subtype 1: 2-amino-4-(4-methoxyphenyl)-7-(naphthalen-1-yl)-5-oxo-5,6,7,8-tetrahydro-4H-chromene-3-carbonitrile (UCPH-101)

    Erichsen, M. N., Huynh, T. H. V., Abrahamsen, B., Bastlund, J. F., Bundgaard, C., Monrad, O., Bekker-Jensen, A., Nielsen, C. W., Frydenvang, Karla Andrea, Jensen, Anders A. & Bunch, Lennart, 2010, In : Journal of Medicinal Chemistry. 53, 19, p. 7180–7191

    Research output: Contribution to journalJournal article

  21. Published

    Structure-Activity Relationship Study of Ionotropic Glutamate Receptor Antagonist (2S,3R)-3-(3-Carboxyphenyl)pyrrolidine-2-carboxylic Acid

    Krogsgaard-Larsen, N., Storgaard, M., Møller, C., Demmer, C. S., Hansen, J., Han, L., Monrad, R. N., Nielsen, Birgitte, Tapken, D., Pickering, Darryl S, Kastrup, Jette Sandholm Jensen, Frydenvang, Karla Andrea & Bunch, Lennart, 2015, In : Journal of Medicinal Chemistry. 58, 15, p. 6131-50 20 p.

    Research output: Contribution to journalJournal article

  22. Published

    Structure of a High-Affinity Kainate Receptor: GluK4 Ligand-Binding Domain Crystallized with Kainate

    Kristensen, O., Kristensen, L. B., Møllerud, Stine, Frydenvang, Karla Andrea, Pickering, Darryl S & Kastrup, Jette Sandholm Jensen, 2016, In : Structure. 24, 9, p. 1582-1589 8 p.

    Research output: Contribution to journalJournal article

  23. Accepted/In press
  24. Published

    Structure and affinity of two bicyclic glutamate analogues at AMPA and kainate receptors

    Møllerud, Stine, Pinto, A., Marconi, L., Frydenvang, Karla Andrea, Thorsen, Thor Seneca, Laulumaa, S. K., Venskutonyte, R., Winther, Nikolaj Sebastian, Cunado Moral, A. M., Tamborini, L., Conti, P., Pickering, Darryl S & Kastrup, Jette Sandholm Jensen, 2017, In : A C S Chemical Neuroscience. 8, 9, p. 2056-2064 9 p.

    Research output: Contribution to journalJournal article

  25. Published

    Structural characterisation and dehydration behaviour of siramesine hydrochloride

    Zimmermann, A., Tian, F., Lopez de Diego, H., Frydenvang, Karla Andrea, Rantanen, Jukka, Elema, M. R. & Hovgaard, L., 2009, In : Journal of Pharmaceutical Sciences. 98, 10, p. 3596-3607

    Research output: Contribution to journalJournal article

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