Kristian Strømgaard

Kristian Strømgaard

Professor


  1. Published

    Analogues of neuroactive polyamine wasp toxins that lack inner basic sites exhibit enhanced antagonism toward a muscle-type mammalian nicotinic acetylcholine receptor. / Stromgaard, K; Brierley, M J; Andersen, K; Sløk, F A; Mellor, I R; Usherwood, P N; Krogsgaard-Larsen, P; Jaroszewski, J W.

    In: Journal of Medicinal Chemistry, Vol. 42, No. 25, 16.12.1999, p. 5224-5234.

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Published

    Site-specific incorporation of unnatural amino acids into proteins. / Strømgaard, Anne; Jensen, Anders A.; Strømgaard, Kristian.

    In: ChemBioChem, Vol. 5, No. 7, 2004, p. 909-16.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Recent advances in the medicinal chemistry of polyamine toxins. / Strømgaard, K; Andersen, K; Krogsgaard-Larsen, P; Jaroszewski, J W.

    In: Mini - Reviews in Medicinal Chemistry, Vol. 1, No. 4, 11.2001, p. 317-338.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Solid-phase synthesis and biological evaluation of a combinatorial library of philanthotoxin analogues. / Strømgaard, K; Brier, T J; Andersen, K; Mellor, I R; Saghyan, A; Tikhonov, D; Usherwood, P N; Krogsgaard-Larsen, P; Jaroszewski, J W.

    In: Journal of Medicinal Chemistry, Vol. 43, No. 23, 16.11.2000, p. 4526-4533.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Solid phase synthesis and biological evaluation of enantiomerically pure wasp toxin analogues PhTX-343 and PhTX-12. / Strømgaard, K; Bjørnsdottir, I; Andersen, K; Brierley, M J; Rizoli, S; Eldursi, N; Mellor, I R; Usherwood, P N; Hansen, S H; Krogsgaard-Larsen, P; Jaroszewski, J W.

    In: Chirality, Vol. 12, No. 2, 02.2000, p. 93-102.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Giftstoffer fra hvepse og edderkopper i forskning og lægemiddeludvikling. / Strømgaard, Kristian.

    In: Carlsbergfondet. Aarsskrift, 2008, p. 42-47.

    Research output: Contribution to journalJournal articleCommunication

  7. Published

    Solid-phase synthesis and pharmacological evaluation of analogues of PhTX-12-A potent and selective nicotinic acetylcholine receptor antagonist. / Strømgaard, Kristian; Mellor, Ian R; Andersen, Kim; Neagoe, Ioana; Pluteanu, Florentina; Usherwood, Peter N R; Krogsgaard-Larsen, Povl; Jaroszewski, Jerzy W.

    In: Bioorganic & Medicinal Chemistry Letters, Vol. 12, No. 8, 22.04.2002, p. 1159-1162.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    AMPA receptor ligands : synthetic and pharmacological studies of polyamines and polyamine toxins. / Strømgaard, Kristian; Mellor, Ian.

    In: Medicinal Research Reviews, Vol. 24, No. 5, 09.2004, p. 589-620.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Ginkgolide derivatives for photolabeling studies : preparation and pharmacological evaluation. / Strømgaard, Kristian; Saito, D Roland; Shindou, Hideo; Ishii, Satoshi; Shimizu, Takao; Nakanishi, Koji.

    In: Journal of Medicinal Chemistry, Vol. 45, No. 18, 29.08.2002, p. 4038-4046.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Polyamine toxins : development of selective ligands for ionotropic receptors. / Strømgaard, Kristian; Jensen, Lars S; Vogensen, Stine B.

    In: Toxicon, Vol. 45, No. 3, 01.03.2005, p. 249-254.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Chemistry and biology of terpene trilactones from Ginkgo biloba. / Strømgaard, Kristian; Nakanishi, Koji.

    In: Angewandte Chemie International Edition, Vol. 43, No. 13, 19.03.2004, p. 1640-1658.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Preparation of a tritiated ginkgolide. / Strømgaard, Kristian; Suehiro, Makiko; Nakanishi, Koji.

    In: Bioorganic & Medicinal Chemistry Letters, Vol. 14, No. 22, 15.11.2004, p. 5673-5675.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    A heteromeric snake toxin and the molecular details of pain perception. / Strømgaard, Kristian; Kristensen, Anders Skov.

    In: Angewandte Chemie International Edition, Vol. 51, No. 17, 23.04.2012, p. 4009-4011.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Synthesis of polyamines and polyamine toxins. An improved alkylation procedure. / Strømgaard, Kristian; Andersen, TF.

    In: Tetrahedron Letters, Vol. 45, 2004, p. 7929-7933.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Chemical biology. / Strømgaard, Kristian.

    Textbook of drug design and discovery. ed. / Povl Krogsgaard-Larsen; Kristian Strømgaard; Ulf Madsen. 4. ed. Boca Raton : CRC Press, 2010. p. 59-74.

    Research output: Chapter in Book/Report/Conference proceedingBook chapterEducation

  16. Published

    Fatty acid derivatives of dimeric inhibitors of PSD-95. / Strømgaard, Kristian (Inventor); Bach, Anders (Inventor); Nissen, Klaus Bertram (Inventor).

    IPC No.: A61K38/17 . Patent No.: WO2015/078477A1.

    Research output: PatentResearch

  17. Published

    Natural products as tools for studies of ligand-gated ion channels. / Strømgaard, Kristian.

    In: Chemical Record, Vol. 5, No. 4, 2005, p. 229-239.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Protolytic properties of polyamine wasp toxin analogues studied by 13C NMR spectroscopy. / Strømgaard, Kristian; Piazzi, Lorna; Olsen, Christian A; Franzyk, Henrik; Jaroszewski, Jerzy W.

    In: Magnetic Resonance in Chemistry, Vol. 44, No. 11, 2006, p. 1013-22.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    A versatile method for solid phase synthesis of polyamines : neuroactive polyamine toxins as example. / Strømgaard, Kristian; Andersen, K; Ruhland, T; Krogsgaard-Larsen, Povl; Jaroszewski, Jerzy W.

    In: Synthesis, No. 6, 2001, p. 877-884.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Skræddersyede proteiner : uden naturens begrænsninger. / Strømgaard, Kristian; Jensen, Mette Stougård; Kristensen, Anders Skov.

    In: Lægemiddelforskning, 2009, p. 10-12.

    Research output: Contribution to journalJournal articleCommunication

  21. Published

    Preparation of peptide thioesters through fmoc-based solid-phase peptide synthesis by using amino thioesters. / Stuhr-Hansen, N.; Wilbek, T.S.; Strømgaard, K.

    In: European Journal of Organic Chemistry, Vol. 2013, No. 24, 01.08.2013, p. 5290-5294.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Synthetic and mechanistic insight into nosylation of glycine residues. / Stuhr-Hansen, Nicolai; Sølling, Theis Ivan; Strømgaard, Kristian.

    In: Organic & Biomolecular Chemistry, Vol. 11, No. 14, 14.04.2013, p. 2288-2293.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Facile synthesis of α-hydroxy carboxylic acids from the corresponding α-amino acids. / Stuhr-Hansen, Nicolai; Padrah, Shahrokh; Strømgaard, Kristian.

    In: Tetrahedron Letters, Vol. 55, No. 30, 2014, p. 4149-4151.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Mechanistic insight into benzenethiol catalyzed amide bond formations from thioesters and primary amines. / Stuhr-Hansen, Nicolai; Bork, Nicolai; Strømgaard, Kristian.

    In: Organic & Biomolecular Chemistry, Vol. 12, No. 30, 14.08.2014, p. 5745-51.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Synthesis of symmetrical and non-symmetrical bivalent neurotransmitter ligands. / Stuhr-Hansen, Nicolai; Andersen, Jacob; Thygesen, Mikkel Boas; Strømgaard, Kristian.

    In: ChemistrySelect, Vol. 1, No. 3, 2016, p. 407-413.

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    Interaction of antidepressants with the serotonin and norepinephrine transporters : mutational studies of the S1 substrate binding pocket. / Sørensen, Lena; Andersen, Jacob; Thomsen, Mette; Hansen, Stinna M.R.; Zhao, Xiaobei; Sandelin, Albin Gustav; Strømgaard, Kristian; Kristensen, Anders S.

    In: The Journal of Biological Chemistry, Vol. 287, No. 52, 2012, p. 43694-43707.

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Published

    Characterization of intracellular regions in the human serotonin transporter for phosphorylation sites. / Sørensen, Lena; Strømgaard, Kristian; Kristensen, Anders S.

    In: ACS chemical biology, Vol. 9, No. 4, 18.04.2014, p. 935-44.

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. Published

    Interaction of antidepressants with the serotonin and norepinephrine transporters : mutational studies of the S1 substrate binding pocket. / Sørensen, Lena; Andersen, Jacob; Thomsen, Mette; Hansen, Stinna M.R.; Zhao, Xiaobei; Sandelin, Albin Gustav; Strømgaard, Kristian; Kristensen, Anders Skov.

    In: Journal of Biological Chemistry, Vol. 287, 2012, p. 43694-43707.

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. Published

    Identification of a small-molecule inhibitor of the PICK1 PDZ domain that inhibits hippocampal LTP and LTD. / Thorsen, Thor S; Madsen, Kenneth L; Rebola, Nelson; Rathje, Mette; Anggono, Victor; Bach, Anders; Moreira, Irina S; Stuhr-Hansen, Nicolai; Dyhring, Tino; Peters, Dan; Beuming, Thijs; Huganir, Richard; Weinstein, Harel; Mulle, Christophe; Strømgaard, Kristian; Rønn, Lars Christian B; Gether, Ulrik.

    In: Proceedings of the National Academy of Science of the United States of America, Vol. 107, No. 1, 2010, p. 413-8.

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. Published

    A fluorescence polarization based screening assay for identification of small molecule inhibitors of the PICK1 PDZ domain. / Thorsen, Thor S; Madsen, Kenneth L; Dyhring, Tino; Bach, Anders; Peters, Dan; Strømgaard, Kristian; Rønn, Lars Christian B; Gether, Ulrik.

    In: Combinatorial Chemistry & High Throughput Screening, Vol. 14, No. 7, 01.08.2011, p. 590-600.

    Research output: Contribution to journalJournal articleResearchpeer-review

  31. Published

    Ligand binding to the PDZ domains of postsynaptic density protein 95. / Toto, Angelo; Pedersen, Søren W; Karlsson, O Andreas; Moran, Griffin E; Andersson, Eva; Chi, Celestine N; Strømgaard, Kristian; Gianni, Stefano; Jemth, Per.

    In: Protein Engineering Design and Selection (Print), Vol. 29, No. 5, 05.2016, p. 169-75.

    Research output: Contribution to journalJournal articleResearchpeer-review

  32. Published

    Preparation of 7-substituted ginkgolide derivatives : potent platelet activating factor (PAF) receptor antagonists. / Vogensen, Stine Byskov; Strømgaard, Kristian; Shindou, Hideo; Jaracz, Stanislav; Suehiro, Makiko; Ishii, Satoshi; Shimizu, Takao; Nakanishi, Koji.

    In: Journal of Medicinal Chemistry, Vol. 46, No. 4, 13.02.2003, p. 601-608.

    Research output: Contribution to journalJournal articleResearchpeer-review

  33. Published

    Identification and characterization of a small-molecule inhibitor of death-associated protein kinase 1. / Wilbek, Theis S; Skovgaard, Tine; Sorrell, Fiona J; Knapp, Stefan; Berthelsen, Jens; Strømgaard, Kristian.

    In: ChemBioChem, Vol. 16, No. 1, 02.01.2015, p. 59-63.

    Research output: Contribution to journalJournal articleResearchpeer-review

  34. Published

    Structure–Activity Relationship Studies of the Natural Product G q/11 Protein Inhibitor YM-254890. / Xiong, Xiao Feng; Zhang, Hang; Boesgaard, Michael W.; Underwood, Christina R.; Bräuner-Osborne, Hans; Strømgaard, Kristian.

    In: ChemMedChem, Vol. 14, No. 8, 04.2019, p. 865-870.

    Research output: Contribution to journalJournal articleResearchpeer-review

  35. Published

    Polyamine toxins from spiders and wasps : Polyamine toxins from spiders and wasps. / Xiong, Xiaofeng; Strømgaard, Kristian.

    Polyamines: A Universal Molecular Nexus for Growth, Survival, and Specialized Metabolism. Springer, Japan, 2015. p. 201-214.

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  36. Published

    Structure–Activity Relationship Study of Spider Polyamine Toxins as Inhibitors of Ionotropic Glutamate Receptors. / Xiong, Xiaofeng; Poulsen, Mette H; Hussein, Rama A; Nørager, Niels G; Strømgaard, Kristian.

    In: ChemMedChem, Vol. 9, No. 12, 12.2014, p. 2661-70.

    Research output: Contribution to journalJournal articleResearchpeer-review

  37. Published

    Total synthesis and structure–activity relationship studies of a series of selective G protein inhibitors. / Xiong, Xiaofeng; Zhang, Hang; Underwood, Christina R.; Harpsøe, Kasper; Gardella, Thomas J.; Wöldike, Mie F.; Mannstadt, Michael; Gloriam, David E.; Bräuner-osborne, Hans; Strømgaard, Kristian.

    In: Nature Chemistry, Vol. 8, No. 11, 2016, p. 1035-1041.

    Research output: Contribution to journalJournal articleResearchpeer-review

  38. Published

    Structure-Activity Relationship Studies of the Cyclic Depsipeptide Natural Product YM-254890, Targeting the Gq Protein. / Zhang, Hang; Xiong, Xiao-feng; Boesgaard, Michael W; Underwood, Christina R; Bräuner-Osborne, Hans; Strømgaard, Kristian.

    In: ChemMedChem, Vol. 12, No. 11, 07.06.2017, p. 830-834.

    Research output: Contribution to journalJournal articleResearchpeer-review

  39. Published

    Structure–activity relationship and conformational studies of the natural product cyclic depsipeptides YM-254890 and FR900359. / Zhang, Hang; Nielsen, Alexander L.; Boesgaard, Michael W.; Harpsøe, Kasper; Daly, Norelle L.; Xiong, Xiao-feng; Underwood, Christina R.; Haugaard-kedström, Linda M.; Bräuner-osborne, Hans; Gloriam, David E.; Strømgaard, Kristian.

    In: European Journal of Medicinal Chemistry, Vol. 156, 05.08.2018, p. 847-860.

    Research output: Contribution to journalJournal articleResearchpeer-review

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